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pro vyhledávání: '"Alcane Ishihara"'
Autor:
Toshihiro Sakamoto, Hisashi Iwaasa, Minoru Moriya, Takunobu Shibata, Masato Chiba, Tomoyuki Ohe, Takehiro Fukami, Yuko Mitobe, Akio Kanatani, Alcane Ishihara, Yasuyuki Ishii, Hidefumi Kitazawa, Hirobumi Takahashi, Katsumasa Nonoshita, Yuji Haga
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5436-5439
A series of trans -3-oxospiro[(aza)isobenzofuran-1(3 H ),1′-cyclohexane]-4′-carboxamide derivatives were synthesized and profiled for NPY Y5 binding affinity, brain and CSF penetrability in rats, and susceptibility to human and mouse P-glycoprote