Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain

Autor: Rodon, Jordi, Mykytyn, Anna Z, Te, Nigeer, Okba, Nisreen M A, Lamers, Mart M, Pailler-García, Lola, Cantero, Guillermo, Albulescu, Irina, Bosch, Berend-Jan, Peiris, Malik, Bensaid, Albert, Vergara-Alert, Júlia, Haagmans, Bart L, Segalés, Joaquim, Virologie

Publikováno v: Emerging Infectious Diseases, 29(3), 585. Centers for Disease Control and Prevention (CDC)
Emerging Infectious Diseases, 29(3), 585-589. Centers for Disease Control and Prevention (CDC)

Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended shedding of MERS-CoV clade B viruses in llamas, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8909fd3279475dfb085df94f98bda823
https://doi.org/10.3201/eid2903.220986

Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas

Autor: Rodon, Jordi, Mykytyn, Anna Z, Cantero, Guillermo, Albulescu, Irina C, Bosch, Berend-Jan, Brix, Alexander, Audonnet, Jean-Christophe, Bensaid, Albert, Vergara-Alert, Júlia, Haagmans, Bart L, Segalés, Joaquim, Virologie, dI&I I&I-1

Publikováno v: One Health Outlook, 4(1), 1
One Health Outlook
IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)

Ongoing outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) continue posing a global health threat. Vaccination of livestock reservoir species is a recommended strategy to prevent spread of MERS-CoV among animals and potential spillo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff725f5b7d152fbfe368f04099a1d6a
https://dspace.library.uu.nl/handle/1874/421358

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

Autor: Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, Li, Wentao, Okba, Nisreen M A, Albulescu, Irina, Widjaja, Ivy, van Dieren, Brenda, Fernandez-Delgado, Raul, Sola, Isabel, Hurdiss, Daniel L, Daramola, Olalekan, Grosveld, Frank, van Kuppeveld, Frank J M, Haagmans, Bart L, Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan, Virologie, dI&I I&I-1, LS Virologie

Publikováno v: Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications, 12(1):1715. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

The coronavirus spike glycoprotein, located on the virion surface, is the key mediator of cell entry and the focus for development of protective antibodies and vaccines. Structural studies show exposed sites on the spike trimer that might be targeted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607a4a50c04793105b0130153cb2cd7f
https://dspace.library.uu.nl/handle/1874/411705

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