Effects of Erythropoietin in Murine-Induced Pluripotent Cell-Derived Panneural Progenitor Cells

Autor: Nils Offen, Johannes Flemming, Hares Kamawal, Ruhel Ahmad, Wanja Wolber, Christian Geis, Holm Zaehres, Hans R. Schöler, Hannelore Ehrenreich, Albrecht M. Müller, Anna-Leena Sirén

Publikováno v: Molecular Medicine, Vol 19, Iss 1, Pp 399-408 (2013)

Abstract Induced cell fate changes by reprogramming of somatic cells offers an efficient strategy to generate autologous pluripotent stem (iPS) cells from any adult cell type. The potential of iPS cells to differentiate into various cell types is wel

Externí odkaz: https://doaj.org/article/07da94e9de7049ff8178c513fd1b70c5

Hematopoietic Stem Cells in Regenerative Medicine: Astray or on the Path?

Autor: Reinhard Henschler, Sascha Huppertz, Albrecht M. Müller

Publikováno v: Transfusion Medicine and Hemotherapy. 43:247-254

Hematopoietic stem cells (HSCs) are the best characterized adult stem cells and the only stem cell type in routine clinical use. The concept of stem cell transplantation laid the foundations for the development of novel cell therapies within, and eve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf9966f0c9d69eb057a1faf85a607e1
https://doi.org/10.1159/000447748

Fostering Responsible Research with Genome Editing Technologies: a European Perspective

Autor: Mylene Botbol-Baum, Marion Abecassis, Johannes Rath, Ewa Bartnik, François Hirsch, Agnes Saint-Raymond, Albrecht M. Müller, Jennifer Merchant, Hervé Chneiweiss, Mihalis Kritikos, Bernard Baertschi, Ana Sofia Carvalho, Christiane Druml, James A. Houghton, Solveig Fenet, Lluis Montoliu, Bärbel Friedrich, Dirk Lanzerath, Janet Mifsud

Publikováno v: Transgenic Research
Transgenic Research, Springer Verlag, 2017, Epub ahead of print. ⟨10.1007/s11248-017-0028-z⟩
Transgenic Research, Vol. 26, no.5, p. 709-713 (2017)
Transgenic Research, 2017, Epub ahead of print. ⟨10.1007/s11248-017-0028-z⟩

In this consensus paper resulting from a meeting that involved representatives from more than 20 European partners, we recommend the foundation of an expert group (European Steering Committee) to assess the potential benefits and draw-backs of genome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71677253c7a66ef29ed3d6c38b54bdef
https://www.hal.inserm.fr/inserm-01586239

Two-Dimensional Polymer-Based Cultures Expand Cord Blood-Derived Hematopoietic Stem Cells and Support Engraftment of NSG Mice

Autor: Wolfgang Wagner, Willi Jahnen-Dechent, Norina Labude, Mónica S. Ventura Ferreira, Ruth Knüchel, Martin Zenke, Sabine Neuss, Rebekka K. Schneider, Manfred Bovi, Albrecht M. Müller, Daniela Piroth, Thomas Hieronymus

Publikováno v: Tissue Engineering Part C: Methods. 19:25-38

Currently, ex vivo expansion of hematopoietic stem cells (HSC) is still insufficient. Traditional approaches for HSC expansion include the use of stromal cultures, growth factors, and/or bioreactors. Biomaterial-based strategies provide new perspecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4a2a92332cd8fbdb5e577865b6ca29
https://doi.org/10.1089/ten.tec.2011.0706

Ex vivoexpansion of cord blood-CD34+cells using IGFBP2and Angptl-5 impairs short-term lymphoid repopulationin vivo

Autor: Martin Zenke, Carina Adamzyk, Ruth Knüchel, Thomas Hieronymus, Mónica S. Ventura Ferreira, Wolfgang Wagner, Albrecht M. Müller, Sabine Neuss, Norina Labude, Gudrun Walenda, Willi Jahnen-Dechent, Daniela Piroth

Publikováno v: Journal of Tissue Engineering and Regenerative Medicine. 7:944-954

Cord blood-derived haematopoietic stem cells (CB-HSCs) are an attractive source for transplantation in haematopoietic disorders. However, the yield of CB-HSCs per graft is limited and often insufficient, particularly for the treatment of adult patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87be735e43b2a79a5a90dd9179c7d52d
https://doi.org/10.1002/term.1486