Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Albrecht Gruhler"'
1
Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study
Autor: Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan
Publikováno v: Journal of the American Society for Mass Spectrometry. 33:1659-1677
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted in traditional p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb68de4c53ee4678b9e74066d51588
https://doi.org/10.1021/jasms.2c00129
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2
New Peak Detection Performance Metrics from the MAM Consortium Interlaboratory Study
Autor: Irina Perdivara, Ben Niu, Kim F. Haselmann, St John Skilton, Anthony Leone, Gregory O. Staples, Carsten P. Sønksen, Helena Maria Barysz, Andrew Hanneman, Chun Shao, Rebecca Scott, Anders Lund, Carly Daniels, Michael Jahn, Da Ren, Nunzio Sepe, K. Ilker Sen, Zoran Sosic, David Ripley, Jing Zhen, Margo Wilson, Melissa Alvarez, John G Hoogerheide, Xinbi Li, Harini Kaluarachchi, Josh Woods, Wenqin Ni, Albrecht Gruhler, Keith A. Johnson, Arnd Brandenburg, Kristen Nields, Michelle Busch, Douglas D. Richardson, Yan Wang, Ahmet Cansizoglu, Xiaoxiao Li, Greg W Adams, Simon Letarte, Joe Shambaugh, Hua Yuan, Trina Mouchahoir, Tom Robinson, Xiaoshi Wang, Nancy S. Nightlinger, Alexander Julian Veach, Chris Chumsae, Eric Carlson, Dongdong Wang, Sean Shen, Jing Fang, Wei Wu, Stefano Gotta, Justin B. Sperry, Hirsh Nanda, X. Christopher Yu, Sibylle Heidelberger, Bhumit A. Patel, Jihong Wang, Sean McCarthy, Himakshi Patel, Thomas N. Krogh, Hunter Walker, Olga V. Friese, Daniela Tizabi, Yali Lu, Kristin Boggio, Ernest L. Maynard, Rich Rogers, Ying Zhou, Nick DeGraan-Weber, John E. Schiel, Weibin Chen, Jason C. Rouse, Li Tao, Thomas W. Powers, John Kim, Xu Guo, Bo Yan, Gabriella Leo, Ying Zhang, Oleg V. Borisov, Ying Qing Yu, Martha Stapels, Wael Yared, Yan-Hui Liu, Alan Heckert, Sarah Rogstad, Li Zang, Aaron Ammerman, Li Cao, Benjamin J. Place, Richard Ludwig, Anton V. Manuilov, Andrew Mahan, Andrew Dawdy, Yi Wang, Brian Schmidt, Peiran Liu
Publikováno v: Journal of the American Society for Mass Spectrometry. 32:913-928
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies to facilitate widespread integration of the MAM platform, which is an emerging ultra-hig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf4a0ab2df01bdb011465e0f168239
https://doi.org/10.1021/jasms.0c00415
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3
In silico and in vitro immunogenicity assessment of B-domain-modified recombinant factor VIII molecules
Autor: J. Wang, Kasper Lamberth, C. Bartholdy, Stine Louise Reedtz-Runge, L. Hjerrild Zeuthen, C. N. Gudme, Albrecht Gruhler
Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 24(5)
Introduction B-domain modification can improve production of recombinant factor VIII (rFVIII) proteins. However, the engineered junction results in non-native peptide sequences with the potential to elicit immune responses via major histocompatibilit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0bf0660e89fa0c0602cca0d5ef2583
https://pubmed.ncbi.nlm.nih.gov/30024643
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6
A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat
Autor: Alexander Amberg, Maximilian Sieber, Laura Suter, Willem G. Schoonen, Nicolas Sajot, Diane McCarthy, Kirstin Meyer, Hans Gmuender, Arnd Brandenburg, Eric Boitier, Marian Raschke, Craig E. Thomas, Valerie Barbié, Albrecht Gruhler, Arne Blichenberg, Bjoern Riefke
Publikováno v: Toxicology and Applied Pharmacology. 252:85-96
The main goal of the present work was to better understand the molecular mechanisms underlying liver hypertrophy (LH), a recurrent finding observed following acute or repeated drug administration to animals, using transcriptomic technologies together
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8429e467c1445343f26443640a3c21
https://doi.org/10.1016/j.taap.2011.01.021
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7
Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor
Autor: Louise Hjerrild Zeuthen, John A. Hamilton, Jesper Pass, Heidi S. Schultz, Louise Maymann Nitze, Andrew J. Fleetwood, Jianhe Chen, Martin W. Berchtold, Svetlana Panina, Albrecht Gruhler, Pernille Keller, Li Guo
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 194(7)
Osteoclast-associated receptor (OSCAR) is widely expressed on human myeloid cells. Collagen types (Col)I, II, and III have been described as OSCAR ligands, and ColII peptides can induce costimulatory signaling in receptor activator for NF-κB–depen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bf5b6a4fddf27080405c3d88c94e38
https://pubmed.ncbi.nlm.nih.gov/25725106
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8
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
Autor: Alexandre V. Podtelejnikov, Peter A Nielsen, Ronald C. Hendrickson, Kelly Boutilier, Anna Millar, Albrecht Gruhler, Lynda Moore, Eva Nielsen, Zhen Lin, Paul J. Taylor, Daniel Durocher, Tony Pawson, Ian Donaldson, Birgitte D Sørensen, Michael Moran, Brenda Muskat, Matthias Mann, Andrew Willems, Daniel Figeys, Juanita Shewnarane, Adrian Heilbut, Marilyn Goudreault, Mai Vo, Jesper Matthiesen, Søren Schandorff, Mike Tyers, Holly Sassi, Lingyun Yang, Christopher W. V. Hogue, Frank Gleeson, Karina Juhl Rasmussen, Katerina Michalickova, Janne S. Crawford, Sally-Lin Adams, Lykke Haastrup Hansen, Keiryn L. Bennett, Yuen Ho, Vibeke Poulsen, Danielle Dewar, Cheryl Wolting, Joanne Taggart, Cris Alfarano, Lene E. Johansen, Jens R. Andersen, Gary D. Bader, Hans Jespersen
Publikováno v: Ho, Y, Gruhler, A, Heilbut, A, Bader, G D, Moore, L, Adams, S-L, Millar, A, Taylor, P, Bennett, K, Boutilier, K, Yang, L, Wolting, C, Donaldson, I, Schandorff, S, Shewnarane, J, Vo, M, Taggart, J, Goudreault, M, Muskat, B, Alfarano, C, Dewar, D, Lin, Z, Michalickova, K, Willems, A R, Sassi, H, Nielsen, P A, Rasmussen, K J, Andersen, J R, Johansen, L E, Hansen, L H, Jespersen, H, Podtelejnikov, A, Nielsen, E, Crawford, J, Poulsen, V, Sørensen, B D, Matthiesen, J, Hendrickson, R C, Gleeson, F, Pawson, T, Moran, M F, Durocher, D, Mann, M, Hogue, C W V, Figeys, D & Tyers, M 2002, ' Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry ', Nature, vol. 415, no. 6868, pp. 180-3 . https://doi.org/10.1038/415180a
Udgivelsesdato: 2002-Jan-10 The recent abundance of genome sequence data has brought an urgent need for systematic proteomics to decipher the encoded protein networks that dictate cellular function. To date, generation of large-scale protein-protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1685a9a7bad1e109003d29257fe03331
https://doi.org/10.1038/415180a
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9
Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle
Autor: Nigel G. Laing, Albrecht Gruhler, Hanns Lochmüller, Bettina Mendel, Rolf Stucka, Michaela Jaksch, Kristen J. Nowak, Christian Thirion, N. Binz
Publikováno v: European Journal of Biochemistry. 268:3473-3482
Cofilins are actin binding proteins and regulate actin assembly in vivo. Numerous cofilin homologues have been characterized in various organisms including mammals. In mice, a ubiquitously expressed cofilin (CFL1) and a skeletal muscle specific cofil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a1cee9ccc373884bfdd101c22c8c43e
https://doi.org/10.1046/j.1432-1327.2001.02247.x
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10
A comparison of viral immune escape strategies targeting the MHC class I assembly pathway
Autor: Raman Murli Krishna, Klaus Früh, Gary J. Schoenhals, Albrecht Gruhler
Publikováno v: Immunological Reviews. 168:157-166
Peptide fragments from proteins of intracellular pathogens such as viruses are displayed at the cell surface by MHC class I molecules thus enabling surveillance by cytotoxic T cells. Peptides are produced in the cytosol by proteasomal degradation and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754009b5e86ca8b05f761c32bfcba320
https://doi.org/10.1111/j.1600-065x.1999.tb01290.x
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