Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Albrecht Bergner"'
Publikováno v:
Cellular Oncology, Vol 31, Iss 4, Pp 301-315 (2009)
Background: Chemotherapy often leads to encouraging responses in lung cancer. But, in the course of the treatment, resistance to chemotherapy ultimately limits the life expectancy of the patient. We aimed at investigating if treatment with cisplatin
Externí odkaz:
https://doaj.org/article/1a4e7cb95b2d48bb9bba53e0b89cd574
Publikováno v:
Technology in Cancer Research & Treatment. 10:275-279
Three-dimensional organ cultures allow performing research in vitro in a complex multi-cellular environment. We aimed at developing a long term coculture system (COC) for the study of lung cancer to repeatedly measure tumor volume. Organ cultures of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969d745a229e22118785c77f210460d9
https://doi.org/10.7785/tcrt.2012.500203
https://doi.org/10.7785/tcrt.2012.500203
Autor:
Fei Tian, Albrecht Bergner, Joachim W. Ellwart, Rudolf M. Huber, Josef Mysliwietz, Fernando Gamarra
Publikováno v:
Clinical and Experimental Medicine. 12:25-30
The hedgehog (Hh) signaling pathway has been shown to be activated in the cancer stem cells of several tumor entities. The Hh inhibitor GDC-0449 has been proven to be effective in some cancers but not yet in lung cancer. We aimed at investigating whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399c6e9f256bac0195968853bef5733e
https://doi.org/10.1007/s10238-011-0135-8
https://doi.org/10.1007/s10238-011-0135-8
Autor:
C Brunner, Hamza Oelmez, Wilfried Szymczak, Albrecht Bergner, Vera Höllriegl, Christoph Hoeschen, Rudolf M. Huber, S. Mörtl, Uwe Oeh
Publikováno v:
Analytical and Bioanalytical Chemistry. 397:2315-2324
Proton transfer reaction mass spectrometry (PTR-MS) has been used to analyze the volatile organic compounds (VOCs) emitted by in-vitro cultured human cells. For this purpose, two pairs of cancerous and non-cancerous human cell lines were selected:1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dc274dc01df35b2152b440c2df1544
https://doi.org/10.1007/s00216-010-3838-x
https://doi.org/10.1007/s00216-010-3838-x
Autor:
Rudolf M. Huber, J Kellner, Albrecht Bergner, Rainald Fischer, M. Edelmann, Hamza Oelmez, Juliane Tantzscher
Publikováno v:
Respiration. 76:205-215
Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0ad8513b232a4bd824783f7660174d1
https://doi.org/10.1159/000135606
https://doi.org/10.1159/000135606
Autor:
Albrecht Bergner, J Kellner, Rudolf A. Jörres, Fernando Gamarra, Rudolf M. Huber, Ulrich Welsch
Publikováno v:
International Archives of Allergy and Immunology. 142:199-210
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13Rα2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13Rα2 remains vague. Methods: B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef29650aeeafa3559a9e226c6349973
https://doi.org/10.1159/000097022
https://doi.org/10.1159/000097022
Publikováno v:
Pneumologie. 60:711-715
Background Airway smooth muscle cells (ASMC) play a key role in bronchial hyperresponsiveness (BHR). A major component of the signalling cascade leading to ASMC contraction is calcium. T-bet knock-out (KO) mice show the key features of allergic asthm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc647900e5fc8790b8c1f45bf1141d63
https://doi.org/10.1055/s-2006-944300
https://doi.org/10.1055/s-2006-944300
Autor:
Albrecht Bergner, A. Kemp da Silva, M. Castro, M. Edelmann, Rudolf M. Huber, Veit Hornung, B. Passlick, Fernando Gamarra
Publikováno v:
Radiation Research. 164:391-399
The aim of this study was to investigate whether the three-dimensional structure of the bronchial tissue and the contact of non-malignant with malignant cells influence the effectiveness of radiotherapy. Monolayer cultures of cells of the human bronc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c143a095095d6ff153359331a6907bef
https://doi.org/10.1667/rr3432.1
https://doi.org/10.1667/rr3432.1
Autor:
Albrecht Bergner, Petra Stieber, Dorothea Nagel, Fernando Gamarra, Jutta Stief, Anke Mitlewski, R. M. Huber, Stefan Holdenrieder
Publikováno v:
Tumor Biology. 25:321-326
Nucleosomes, which are typical cell death products, are elevated in the serum of cancer patients and are known to rapidly increase during radiotherapy. As both normal and malignant cells are damaged by irradiation, we investigated to which extent bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8f166404c7d50b6baf10c8ce0e7dcc
https://doi.org/10.1159/000081401
https://doi.org/10.1159/000081401
Autor:
Michael J. Sanderson, Albrecht Bergner
Publikováno v:
Journal of Applied Physiology. 95:1325-1332
To investigate the hypothesis that altered Ca2+ signaling in airway smooth muscle cells (SMCs) is responsible for airway hyperreactivity, we compared, with the use of confocal and phase-contrast microscopy, the airway contractility and Ca2+ changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193503a93093e35a81da387787575cb8
https://doi.org/10.1152/japplphysiol.00272.2003
https://doi.org/10.1152/japplphysiol.00272.2003