Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Albrecht, Piiper"'
Autor:
Christian Schmithals, Bianca Kakoschky, Dominic Denk, Maike von Harten, Jan Henrik Klug, Edith Hintermann, Anne Dropmann, Eman Hamza, Anne Claire Jacomin, Jens U. Marquardt, Stefan Zeuzem, Peter Schirmacher, Eva Herrmann, Urs Christen, Thomas J. Vogl, Oliver Waidmann, Steven Dooley, Fabian Finkelmeier, Albrecht Piiper
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105178- (2024)
Summary: Background: The accuracy of blood-based early tumour recognition is compromised by signal production at non-tumoral sites, low amount of signal produced by small tumours, and variable tumour production. Here we examined whether tumour-specif
Externí odkaz:
https://doaj.org/article/697990059c5e4e25a28e59b2e57c8d91
Autor:
Harri A. Järveläinen, Christian Schmithals, Maike von Harten, Bianca Kakoschky, Thomas J. Vogl, Stephen Harris, Claire Henson, Gemma Bullen-Clerkson, Albrecht Piiper
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5700 (2023)
CEND-1 (iRGD) is a bifunctional cyclic peptide that can modulate the solid tumour microenvironment, enhancing the delivery and therapeutic index of co-administered anti-cancer agents. This study explored CEND-1’s pharmacokinetic (PK) properties pre
Externí odkaz:
https://doaj.org/article/7111239e33b74bd298c5ae10cee5506f
Autor:
Oliver Waidmann, Thomas Pleli, Andreas Weigert, Esther Imelmann, Bianca Kakoschky, Christian Schmithals, Claudia Döring, Matthias Frank, Thomas Longerich, Verena Köberle, Martin-Leo Hansmann, Bernhard Brüne, Stefan Zeuzem, Albrecht Piiper, Ivan Dikic
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepato
Externí odkaz:
https://doaj.org/article/740d319af09b47b9b936f1021dead416
Autor:
Thomas Pleli, Antonia Mondorf, Nerea Ferreiros, Dominique Thomas, Karel Dvorak, Ricardo M. Biondi, Dagmar Meyer zu Heringdorf, Stefan Zeuzem, Gerd Geisslinger, Herbert Zimmermann, Oliver Waidmann, Albrecht Piiper
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 6, Pp 2516-2528 (2018)
Background/Aims: Signaling of Gs protein-coupled receptors (GsPCRs) is accomplished by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular cAMP effectors protein kinase A (PKA)
Externí odkaz:
https://doaj.org/article/0a4e904e6a144be5903bf729f11e5b78
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Supplementary Fig. S3. Doxycyline-induced overexpression of Dicer in HCC cells. HepG2 (A) and Huh-7 (B) cells stably transfected with the inducible Dicer construct were incubated with or without doxycycline (Dox) for 24 h. C: HepG2 cells with the ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153173b78795cd01540a4b2857d672af
https://doi.org/10.1158/1078-0432.22466477.v1
https://doi.org/10.1158/1078-0432.22466477.v1
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Table S1. Clinicopathological parameters of the patients with HCC. HBV, hepatitis B virus; HCV, hepatitis C virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6865ed66d510950ea5367a566e7d6f
https://doi.org/10.1158/1078-0432.22466471
https://doi.org/10.1158/1078-0432.22466471
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Purpose: A role of Dicer, which converts precursor miRNAs to mature miRNAs, in the tumor-promoting effect of hypoxia is currently emerging in some tumor entities. Its role in hepatocellular carcinoma (HCC) is unknown.Experimental Design: HepG2 and Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0051240aeb319e2ddd4c696dd0bad3
https://doi.org/10.1158/1078-0432.c.6526325
https://doi.org/10.1158/1078-0432.c.6526325
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20816ba146821c93fd1d8d962e308247
https://doi.org/10.1158/1078-0432.22466474.v1
https://doi.org/10.1158/1078-0432.22466474.v1
Autor:
Albrecht Piiper, Oliver Waidmann, Thomas J. Vogl, Stefan Zeuzem, Bernd Kronenberger, Horst-Werner Korf, Bernd Groner, Vida Vafaizadeh, Jose M. Arencibia, Ahmed Atef Ibrahim, Eduardo Alonso Augusto, Bianca Kakoschky, Thomas Pleli, Hüdayi Korkusuz, Verena Köberle, Christian Schmithals
Supplementary Figure S3: Body weight of HepG2 (A) and Huh-7 (B) xenograft-bearing mice treated with iRGD, control (Ctl.) peptide, PBS and sorafenib (Sora).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162248249a6792df0df3f94c810a6ab0
https://doi.org/10.1158/0008-5472.22405320
https://doi.org/10.1158/0008-5472.22405320
Autor:
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning
Publikováno v:
HEPATOLOGY
Background and Aims Current liver-directed gene therapies look for adeno-associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3992e2d4051892b5d5ec5800f0ea7bc7
https://biblio.ugent.be/publication/01GTWD9Z2QP1MNJK0ZCMFT6Z89/file/01GTWDBEX9VA0AKWWGCD7WQ036
https://biblio.ugent.be/publication/01GTWD9Z2QP1MNJK0ZCMFT6Z89/file/01GTWDBEX9VA0AKWWGCD7WQ036