Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Albino García-Sacristán"'
Autor:
Claudia Rodríguez, Cristina Contreras, Javier Sáenz-Medina, Mercedes Muñoz, César Corbacho, Joaquín Carballido, Albino García-Sacristán, Medardo Hernandez, Miguel López, Luis Rivera, Dolores Prieto
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101575- (2020)
AMP-activated protein kinase (AMPK) is a cellular energy sensor activated during energy stress to stimulate ATP production pathways and restore homeostasis. AMPK is widely expressed in the kidney and involved in mitochondrial protection and biogenesi
Externí odkaz:
https://doaj.org/article/45834cd73fe84a8b9bd4b67b363fae89
Autor:
Mercedes Muñoz, Maria Elvira López-Oliva, Claudia Rodríguez, María Pilar Martínez, Javier Sáenz-Medina, Ana Sánchez, Belén Climent, Sara Benedito, Albino García-Sacristán, Luis Rivera, Medardo Hernández, Dolores Prieto
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Oxidative stress-associated endothelial dysfunction is a key pathogenic factor underlying the microvascular complications of metabolic disease. NADPH oxidase (Nox) is a major source of oxidative stress in diabetic nephropathy and chronic kidney disea
Externí odkaz:
https://doaj.org/article/473f5a741c204a38aa2f9b5cc20e094b
Autor:
Mercedes Muñoz, María Pilar Martínez, María Elvira López-Oliva, Claudia Rodríguez, César Corbacho, Joaquín Carballido, Albino García-Sacristán, Medardo Hernández, Luis Rivera, Javier Sáenz-Medina, Dolores Prieto
Publikováno v:
Redox Biology, Vol 19, Iss , Pp 92-104 (2018)
The role of NADPH oxidase (Nox)-derived reactive oxygen species in kidney vascular function has extensively been investigated in the harmful context of oxidative stress in diabetes and obesity-associated kidney disease. Since hydrogen peroxide (H2O2)
Externí odkaz:
https://doaj.org/article/f4ac3faaaffb499d841ab2982096d8da
Autor:
Igor Blaha, Paz Recio, María Pilar Martínez, María Elvira López-Oliva, Ana S F Ribeiro, Ángel Agis-Torres, Ana Cristina Martínez, Sara Benedito, Albino García-Sacristán, Vítor S Fernandes, Medardo Hernández
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157424 (2016)
Metabolic syndrome (MS) is a known risk factor for lower urinary tract symptoms. This study investigates whether functional and expression changes of cannabinoid CB1 and CB2 receptors are involved in the bladder dysfunction in an obese rat model with
Externí odkaz:
https://doaj.org/article/ee79347c3e974c57b704dd6da5883c0d
Autor:
Ana Cristina Martínez, Rosa María Pagán, Dolores Prieto, Paz Recio, Albino García-Sacristán, Medardo Hernández, Sara Benedito
Publikováno v:
Journal of Pharmacological Sciences, Vol 111, Iss 3, Pp 299-311 (2009)
The present study was designed to characterize the neurogenic contraction of rat radial artery. Electrical field stimulation (EFS) evoked frequency-dependent contraction that was abolished by tetrodotoxin (neuronal Na+ channel blocker), guanethidine
Externí odkaz:
https://doaj.org/article/c3a3facc8d584cf1ad5ebebc65cb27b0
Autor:
Belén Climent, Laura Moreno, Pilar Martínez, Cristina Contreras, Ana Sánchez, Francisco Pérez-Vizcaíno, Albino García-Sacristán, Luis Rivera, Dolores Prieto
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109432 (2014)
Background and aimsEndothelial small- and intermediate-conductance KCa channels, SK3 and IK1, are key mediators in the endothelium-derived hyperpolarization and relaxation of vascular smooth muscle and also in the modulation of endothelial Ca2+ signa
Externí odkaz:
https://doaj.org/article/d39e580b192145d9bede6cb891057c6a
Autor:
Vítor S Fernandes, Ana S F Ribeiro, Pilar Martínez, María Elvira López-Oliva, María Victoria Barahona, Luis M Orensanz, Ana Martínez-Sáenz, Paz Recio, Sara Benedito, Salvador Bustamante, Albino García-Sacristán, Dolores Prieto, Medardo Hernández
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113580 (2014)
According to previous observations nitric oxide (NO), as well as an unknown nature mediator are involved in the inhibitory neurotransmission to the intravesical ureter. This study investigates the hydrogen sulfide (H2S) role in the neurogenic relaxat
Externí odkaz:
https://doaj.org/article/9f2943b83fb149c18ffa9e36fe941ec8
Autor:
Ana Cristina Martínez, Medardo Hernández, Susana Novella, María Pilar Martínez, Rosa María Pagán, Carlos Hermenegildo, Albino García-Sacristán, Dolores Prieto, Sara Benedito
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106372 (2014)
OBJECTIVE: Peripheral arterial disease is one of the macrovascular complications of type 2 diabetes mellitus. This study addresses femoral artery regulation in a prediabetic model of obese Zucker rats (OZR) by examining cross-talk between endothelial
Externí odkaz:
https://doaj.org/article/3a2c070d4bbf4f9b8f6ab9f14846b295
Autor:
Ana Sánchez, Cristina Contreras, María Pilar Martínez, Belén Climent, Sara Benedito, Albino García-Sacristán, Medardo Hernández, Dolores Prieto
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36027 (2012)
OBJECTIVE: Erectile dysfunction (ED) is considered as an early sign of vascular disease due to its high prevalence in patients with cardiovascular risk factors. Endothelial and neural dysfunction involving nitric oxide (NO) are usually implicated in
Externí odkaz:
https://doaj.org/article/b583e9871ac241509bcfff0a0900c631
Autor:
Albino García Sacristán
Publikováno v:
Anales de la Real Academia Nacional de Farmacia. :135-139
In 1921, Otto Loewi published an experimental study that gave rise to the birth of the chemical theory of nerve transmission, according to which, the nerve current causes, at the end of nerve fibers, the release of a chemical substance called a neuro