Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Albertus Eka Yudistira Sarwono"'
Autor:
Albertus Eka Yudistira Sarwono, Shinya Mitsuhashi, Mohammad Hazzaz Bin Kabir, Kengo Shigetomi, Tadashi Okada, Fumina Ohsaka, Satoko Otsuguro, Katsumi Maenaka, Makoto Igarashi, Kentaro Kato, Makoto Ubukata
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 171-178 (2019)
Inosine 5′-monophosphate dehydrogenase (IMPDH) is an essential enzyme for the production of guanine nucleotides. Disruption of IMPDH activity has been explored as a therapeutic strategy for numerous purposes, such as for anticancer, immunosuppressi
Externí odkaz:
https://doaj.org/article/5853f45477c74c8dbfdc2be048baba82
Publikováno v:
The Journal of Antibiotics. 72:934-942
We have found cyclophane-type adenosine derivatives having p-quinone amide moieties (1 and 2) as weak inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) from the Hokkaido University Chemical Library via the lucifera
Autor:
Mohammad Hazzaz Bin Kabir, Albertus Eka Yudistira Sarwono, Katsumi Maenaka, Makoto Igarashi, Tadashi Okada, Makoto Ubukata, Kentaro Kato, Kengo Shigetomi, Satoko Otsuguro, Fumina Ohsaka, Shinya Mitsuhashi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 171-178 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Inosine 5′-monophosphate dehydrogenase (IMPDH) is an essential enzyme for the production of guanine nucleotides. Disruption of IMPDH activity has been explored as a therapeutic strategy for numerous purposes, such as for anticancer, immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1969cee79fe53dc53bf4b9500072fc9
Autor:
Makoto Ubukata, Shinya Mitsuhashi, Albertus Eka Yudistira Sarwono, Molefe Nthatisi, Tadashi Okada, Marcin Jąkalski, Keisuke Suganuma, Junya Yamagishi, Noboru Inoue
Publikováno v:
Antimicrobial agents and chemotherapy. 60(7):4391-4393
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This study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives for Trypanosoma congolense. The proliferation of T. congolense was completely inhibited by adding
This study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives for Trypanosoma congolense. The proliferation of T. congolense was completely inhibited by adding
Autor:
Albertus Eka Yudistira Sarwono, Makoto Ubukata, Noboru Inoue, Shinya Mitsuhashi, Keisuke Suganuma, Simon Peter Musinguzi, Tadashi Okada, Kengo Shigetomi
Publikováno v:
Parasitology international. 66(5)
Trypanosoma congolense is one of the most prevalent pathogens which causes trypanosomosis in African animals, resulting in a significant economic loss. In its life cycle, T. congolense is incapable of synthesizing purine nucleotides via a de novo pat