Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation.

Autor: Kusuyama J; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.; Division of Biomedical Engineering for Health and Welfare, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan., Makarewicz NS; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Albertson BG; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Alves-Wagner AB; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Conlin RH; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Prince NB; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Alves CRR; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Ramachandran K; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Kozuka C; YCI Laboratory for Metabolic Epigenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Xiudong Y; Graduate School of Biomedical Sciences, University of Texas at Houston, Houston, TX., Xia Y; Graduate School of Biomedical Sciences, University of Texas at Houston, Houston, TX., Hirshman MF; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA., Hatta T; Department of Anatomy, Kanazawa Medical University, Kanazawa, Japan., Nagatomi R; Division of Biomedical Engineering for Health and Welfare, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan.; Department of Medicine and Science in Sports and Exercise, Tohoku University School of Medicine, Sendai, Japan., Nozik ES; Cardiovascular Pulmonary Research Laboratories and Pediatric Critical Care, Department of Pediatrics, University of Colorado Anschutz Medical Center, Aurora, CO., Goodyear LJ; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.

Publikováno v: Diabetes [Diabetes] 2022 Jun 01; Vol. 71 (6), pp. 1170-1181.

Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health.

Autor: Kusuyama J; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Miyagi, Japan. Electronic address: joji.kusuyama.c1@tohoku.ac.jp., Alves-Wagner AB; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Conlin RH; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Makarewicz NS; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Albertson BG; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Prince NB; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Kobayashi S; Section of Immunobiology, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Kozuka C; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA; YCI Laboratory for Metabolic Epigenetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan., Møller M; Department of Gynecology and Obstetrics, Aarhus University Hospital and Clinical Institute, Aarhus University, Aarhus, Denmark., Bjerre M; Medical Research Laboratory, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Fuglsang J; Department of Gynecology and Obstetrics, Aarhus University Hospital and Clinical Institute, Aarhus University, Aarhus, Denmark., Miele E; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Middelbeek RJW; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Xiudong Y; Graduate School of Biomedical Sciences, University of Texas at Houston, Houston, TX, USA., Xia Y; Graduate School of Biomedical Sciences, University of Texas at Houston, Houston, TX, USA., Garneau L; Institut du Savoir Montfort, recherche, Ottawa, Canada; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada., Bhattacharjee J; School of Human Kinetics, Faculty of Health Science University of Ottawa, Ottawa, Canada., Aguer C; Institut du Savoir Montfort, recherche, Ottawa, Canada; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada; School of Human Kinetics, Faculty of Health Science University of Ottawa, Ottawa, Canada; Interdisciplinary School of Health Sciences, Faculty of Health Science University of Ottawa, Ottawa, Canada., Patti ME; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Hirshman MF; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Jessen N; Steno Diabetes Center Aarhus, Department of Biomedicine, Aarhus University, Aarhus, Denmark., Hatta T; Department of Anatomy, Kanazawa Medical University, Ishikawa, Japan., Ovesen PG; Department of Gynecology and Obstetrics, Aarhus University Hospital and Clinical Institute, Aarhus University, Aarhus, Denmark., Adamo KB; School of Human Kinetics, Faculty of Health Science University of Ottawa, Ottawa, Canada., Nozik-Grayck E; Cardiovascular Pulmonary Research Laboratories and Pediatric Critical Care, Department of Pediatrics, University of Colorado Anschutz Medical Center, Aurora, CO, USA., Goodyear LJ; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. Electronic address: laurie.goodyear@joslin.harvard.edu.

Publikováno v: Cell metabolism [Cell Metab] 2021 May 04; Vol. 33 (5), pp. 939-956.e8. Date of Electronic Publication: 2021 Mar 25.

JNK inactivation suppresses osteogenic differentiation, but robustly induces osteopontin expression in osteoblasts through the induction of inhibitor of DNA binding 4 (Id4).

Autor: Kusuyama J; Department of Oral Biochemistry, Field of Developmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.; Department of Medicine, Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA., Amir MS; Department of Oral Biochemistry, Field of Developmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.; Department of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Airlangga University, Surabaya, Indonesia., Albertson BG; Department of Medicine, Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA., Bandow K; Department of Oral Biology and Tissue Engineering, Meikai University School of Dentistry, Saitama, Japan; and., Ohnishi T; Department of Oral Biochemistry, Field of Developmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Nakamura T; Department of Periodontology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Noguchi K; Department of Periodontology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Shima K; Department of Oral Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Semba I; Department of Oral Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Matsuguchi T; Department of Oral Biochemistry, Field of Developmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Jun; Vol. 33 (6), pp. 7331-7347. Date of Electronic Publication: 2019 Mar 18.