Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alberto Visioli"'
Autor:
Mattia Colucci, Nadia Trivieri, Gandino Mencarelli, Elisabetta De Santis, Francesca Sansico, Francesco Tamiro, Alberto Visioli, Chiara Barile, Riccardo Pracella, Giovanni Rossi, Elena Binda, Vincenzo Giambra
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract T-cell lymphoblastic acute leukemia (T-ALL) is an aggressive blood cancer, characterized by restricted cellular subsets with enriched leukemia initiating cells (LICs). Recently, Ephrin receptors (Eph) were described to be highly expressed in
Externí odkaz:
https://doaj.org/article/beb9e41daf6b4f769553c57d5afebeba
Autor:
Alberto Visioli, Nadia Trivieri, Gandino Mencarelli, Fabrizio Giani, Massimiliano Copetti, Orazio Palumbo, Riccardo Pracella, Maria Grazia Cariglia, Chiara Barile, Luigi Mischitelli, Amata Amy Soriano, Pietro Palumbo, Federico Legnani, Francesco DiMeco, Leonardo Gorgoglione, Graziano Pesole, Angelo L. Vescovi, Elena Binda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Glioblastoma (GBM) is the most malignant among gliomas with an inevitable lethal outcome. The elucidation of the physiology and regulation of this tumor is mandatory to unravel novel target and effective therapeutics. Emerging con
Externí odkaz:
https://doaj.org/article/1e15644cd66b4514a5bd641eb828b5a6
Autor:
Eelke M. Bos, Elena Binda, Iris S.C. Verploegh, Eva Wembacher, Daphna Hoefnagel, Rutger K. Balvers, Anne L. Korporaal, Andrea Conidi, Esther A. H. Warnert, Nadia Trivieri, Alberto Visioli, Paola Zaccarini, Laura Caiola, Rogier van Wijck, Peter van der Spek, Danny Huylebroeck, Sieger Leenstra, Martine L.M. Lamfers, Zvi Ram, Manfred Westphal, David Noske, Federico Legnani, Francesco DiMeco, Angelo Luigi Vescovi, Clemens M.F. Dirven
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone Morphogenetic Protein 4 (hrBMP4) – an inhibitory regulator of cancer stem cells (CSCs) – in
Externí odkaz:
https://doaj.org/article/b6e88963f885415e8d912afbaecd0fc3
Autor:
Nadia Trivieri, Alberto Visioli, Gandino Mencarelli, Maria Grazia Cariglia, Laura Marongiu, Riccardo Pracella, Fabrizio Giani, Amata Amy Soriano, Chiara Barile, Laura Cajola, Massimiliano Copetti, Orazio Palumbo, Federico Legnani, Francesco DiMeco, Leonardo Gorgoglione, Angelo L. Vescovi, Elena Binda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Glioblastoma multiforme (GBM) is an incurable tumor, with a median survival rate of only 14–15 months. Along with heterogeneity and unregulated growth, a central matter in dealing with GBMs is cell invasiveness. Thus, improving
Externí odkaz:
https://doaj.org/article/4fd9558a7f4840cbb15f9370a824afff
Autor:
Nadia Trivieri, Riccardo Pracella, Maria Grazia Cariglia, Concetta Panebianco, Paola Parrella, Alberto Visioli, Fabrizio Giani, Amata Amy Soriano, Chiara Barile, Giuseppe Canistro, Tiziana Pia Latiano, Lucia Dimitri, Francesca Bazzocchi, Dario Cassano, Angelo L. Vescovi, Valerio Pazienza, Elena Binda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Colorectal cancer (CRC) harboring BRAF V600E mutation exhibits low response to conventional therapy and poorest prognosis. Due to the emerging correlation between gut microbiota and CRC carcinogenesis, we investigated in serrated
Externí odkaz:
https://doaj.org/article/a77a0a281c8c412ca8f2c6c0e1b53cf4
Autor:
Letizia Mazzini, Maurizio Gelati, Daniela Celeste Profico, Gianni Sorarù, Daniela Ferrari, Massimiliano Copetti, Gianmarco Muzi, Claudia Ricciolini, Sandro Carletti, Cesare Giorgi, Cristina Spera, Domenico Frondizi, Stefano Masiero, Alessandro Stecco, Carlo Cisari, Enrica Bersano, Fabiola De Marchi, Maria Francesca Sarnelli, Giorgia Querin, Roberto Cantello, Francesco Petruzzelli, Annamaria Maglione, Cristina Zalfa, Elena Binda, Alberto Visioli, Domenico Trombetta, Barbara Torres, Laura Bernardini, Alessandra Gaiani, Maurilio Massara, Silvia Paolucci, Nicholas M. Boulis, Angelo L. Vescovi, on behalf of the ALS‐NSCs Trial Study Group
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 9, Pp 887-897 (2019)
Abstract The main objective of this phase I trial was to assess the feasibility and safety of microtransplanting human neural stem cell (hNSC) lines into the spinal cord of patients with amyotrophic lateral sclerosis (ALS). Eighteen patients with a d
Externí odkaz:
https://doaj.org/article/1b266c15eb0b4c92a1cb1b70a47533cf
Autor:
Alberto Visioli, Fabrizio Giani, Nadia Trivieri, Riccardo Pracella, Elide Miccinilli, Maria Grazia Cariglia, Orazio Palumbo, Andrea Arleo, Fabio Dezi, Massimiliano Copetti, Laura Cajola, Silvia Restelli, Valerio Papa, Antonio Sciuto, Tiziana Pia Latiano, Massimo Carella, Dino Amadori, Giulia Gallerani, Riccardo Ricci, Sergio Alfieri, Graziano Pesole, Angelo L. Vescovi, Elena Binda
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 346-360 (2019)
Background: Despite their lethality and ensuing clinical and therapeutic relevance, circulating tumor cells (CTCs) from colorectal carcinoma (CRC) remain elusive, poorly characterized biological entities. Methods and findings: We perfected a cell sys
Externí odkaz:
https://doaj.org/article/1f869219eef84cd3b7742e7ad0525533
Autor:
Angelo L. Vescovi, Rohit Duggal, Francesco Di Meco, Massimo Carella, Federico Legnani, Caterina Fusilli, Tommaso Mazza, Fabio Dezi, Silvia Restelli, Orazio Palumbo, Nadia Trivieri, Fabrizio Giani, Alberto Visioli, Elena Binda
Table S1: Molecular Classification of Low-Grade and Anaplastic Gliomas; Table S2: WNT5A and FRIZZLED5 gene copy number in glioma tissues and hGBM TPCs; Table S3: Ingenuity analysis of the LVWnt5a classical TPCs genes demonstrating the associated canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544abde6c3489094ebc949ae3ad24490
https://doi.org/10.1158/0008-5472.22416875
https://doi.org/10.1158/0008-5472.22416875
Autor:
Angelo L. Vescovi, Rohit Duggal, Francesco Di Meco, Massimo Carella, Federico Legnani, Caterina Fusilli, Tommaso Mazza, Fabio Dezi, Silvia Restelli, Orazio Palumbo, Nadia Trivieri, Fabrizio Giani, Alberto Visioli, Elena Binda
Brain invasion by glioblastoma determines prognosis, recurrence, and lethality in patients, but no master factor coordinating the invasive properties of glioblastoma has been identified. Here we report evidence favoring such a role for the noncanonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861b06f01b57765acd6a0407b7843cfe
https://doi.org/10.1158/0008-5472.c.6509678.v1
https://doi.org/10.1158/0008-5472.c.6509678.v1
Autor:
Angelo L. Vescovi, Rohit Duggal, Francesco Di Meco, Massimo Carella, Federico Legnani, Caterina Fusilli, Tommaso Mazza, Fabio Dezi, Silvia Restelli, Orazio Palumbo, Nadia Trivieri, Fabrizio Giani, Alberto Visioli, Elena Binda
Suppl Fig S1: Levels of Wnt5a expression in brain tumors correlate to aggressiveness or outcome; Suppl Fig S2: Wnt5a overexpression sustains TPCs invasive capability; Suppl Fig S3: Elevated Wnt5a expression promotes migratory capability in otherwise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319bdaf48960d426991fb0a1090db336
https://doi.org/10.1158/0008-5472.22416884.v1
https://doi.org/10.1158/0008-5472.22416884.v1