Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alberto Siddu"'
Autor:
Stefan Bartl, Yuanyun Xie, Nalini Potluri, Ratnesh Kesineni, Katlin Hencak, Louisa Dal Cengio, Katja Balazs, Abid Oueslati, Michela Parth, Nina Salhat, Alberto Siddu, Oskar Smrzka, Francesca Cicchetti, Günther Staffler, Michael R. Hayden, Amber L. Southwell
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106444- (2024)
Externí odkaz:
https://doaj.org/article/9f127a6b6c0642d8b90cf4f316b4916a
Autor:
Stefan Bartl, Yuanyun Xie, Nalini Potluri, Ratnesh Kesineni, Katlin Hencak, Louisa Dal Cengio, Katja Balazs, Abid Oueslati, Michela Parth, Nina Salhat, Alberto Siddu, Oskar Smrzka, Francesca Cicchetti, Günther Straffler, Michael R. Hayden, Amber L. Southwell
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106376- (2024)
In Huntington disease (HD), the mutant huntingtin (mtHTT) protein is the principal cause of pathological changes that initiate primarily along the cortico-striatal axis. mtHTT is ubiquitously expressed and there is, accordingly, growing recognition t
Externí odkaz:
https://doaj.org/article/4d07a71b09d34d4a99a06f94d8778757
Autor:
Marie Rieux, Melanie Alpaugh, Shireen Salem, Alberto Siddu, Martine Saint-Pierre, Hélèna L. Denis, Heike Rohweder, Frank Herrmann, Chantal Bazenet, Steve Lacroix, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106289- (2023)
Externí odkaz:
https://doaj.org/article/20374c4117494cd5af4a06381e01cf57
Autor:
Marie Rieux, Melanie Alpaugh, Shireen Salem, Alberto Siddu, Martine Saint-Pierre, Hélèna L. Denis, Heike Rohweder, Frank Herrmann, Chantal Bazenet, Steve Lacroix, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106091- (2023)
In a previous study, we have shown that parabiotic coupling of a knock-in mouse model (zQ175) of Huntington's disease (HD) to wild-type (WT) littermates resulted in a worsening of the normal phenotype as seen by detection of mutant huntingtin protein
Externí odkaz:
https://doaj.org/article/e49ceef186c14eb781f5cade28f1336a
Autor:
Alberto Siddu, Linda Suzanne David, Nadine Lauinger, Xiuqing Chen, Martine Saint-Pierre, Melanie Alpaugh, Thomas Durcan, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 145, Iss , Pp 105042- (2020)
A number of publications have reported that cysteamine has significant therapeutic effects on several aspects of Parkinson's disease (PD)-related pathology but none of these studies have evaluated its impact on pathological forms of α-Synuclein (α-
Externí odkaz:
https://doaj.org/article/7854854d46ee4f9facea5d547de49e54
Autor:
Stefan Bartl, Abid Oueslati, Amber L. Southwell, Alberto Siddu, Michela Parth, Linda Suzanne David, Alexander Maxan, Nina Salhat, Markus Burkert, Andreas Mairhofer, Theresa Friedrich, Halyna Pankevych, Katja Balazs, Guenther Staffler, Michael R. Hayden, Francesca Cicchetti, Oskar W. Smrzka
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104943- (2020)
Huntington's disease (HD) is caused by a highly polymorphic CAG trinucleotide expansion in the gene encoding for the huntingtin protein (HTT). The resulting mutant huntingtin protein (mutHTT) is ubiquitously expressed but also exhibits the ability to
Externí odkaz:
https://doaj.org/article/7a2a9cc730a442b79298549f98f442c9
Publikováno v:
Sci Transl Med
Mutations in β-amyloid (Aβ) precursor protein (APP) cause familial Alzheimer’s disease (AD) probably by enhancing Aβ peptides production from APP. An antibody targeting Aβ (aducanumab) was approved as an AD treatment; however, some Aβ antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9320ccee388211be6d41d3dc7bf37a1
https://pubmed.ncbi.nlm.nih.gov/36260691
https://pubmed.ncbi.nlm.nih.gov/36260691
Publikováno v:
Science Translational Medicine. 14
Mutations in β-amyloid (Aβ) precursor protein ( APP ) cause familial Alzheimer’s disease (AD) probably by enhancing Aβ peptides production from APP. An antibody targeting Aβ (aducanumab) was approved as an AD treatment; however, some Aβ antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f41430d4f61385c0563f2f5f729f678
https://doi.org/10.1126/scitranslmed.abn9380
https://doi.org/10.1126/scitranslmed.abn9380
Autor:
Francesca Cicchetti, Günther Straffler, Abid Oueslati, Nalini Potluri, Stefan Bartl, Benjamin Gordon, Alberto Siddu, Nina Salhat, Michela Parth, Michael R. Hayden, Katja Balash, Oskar Smrzka, Amber L. Southwell, Yuanyun Xie, Alicia Willenberg
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa2af95fb8a3787c056bc5544ac139a
https://doi.org/10.1136/jnnp-2021-ehdn.123
https://doi.org/10.1136/jnnp-2021-ehdn.123
Autor:
Halyna Pankevych, Stefan Bartl, Amber L. Southwell, Michela Parth, Theresa Friedrich, Alexander Maxan, Michael R. Hayden, Francesca Cicchetti, Guenther Staffler, Andreas Mairhofer, Alberto Siddu, Nina Salhat, Abid Oueslati, Katja Balazs, Markus Burkert, Oskar W. Smrzka, Linda Suzanne David
Publikováno v:
Neurobiology of Disease, Vol 141, Iss, Pp 104943-(2020)
Huntington's disease (HD) is caused by a highly polymorphic CAG trinucleotide expansion in the gene encoding for the huntingtin protein (HTT). The resulting mutant huntingtin protein (mutHTT) is ubiquitously expressed but also exhibits the ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960fa749199bcd14ff701a186072beed
https://pubmed.ncbi.nlm.nih.gov/32407769
https://pubmed.ncbi.nlm.nih.gov/32407769