Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alberto Perez-Alvarez"'
Autor:
Alberto Perez-Alvarez, Shuting Yin, Christian Schulze, John A. Hammer, Wolfgang Wagner, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
In hippocampal pyramidal cells, a subset of dendritic spines contain endoplasmic reticulum (ER). Here, the authors show that ER enters dendritic spines in a non-random manner, during high synaptic activity with the function of limiting synaptic stren
Externí odkaz:
https://doaj.org/article/d18389b28e5c4c748bad163e6a7b8cd6
Autor:
Alberto Perez-Alvarez, Brenna C. Fearey, Ryan J. O’Toole, Wei Yang, Ignacio Arganda-Carreras, Paul J. Lamothe-Molina, Benjamien Moeyaert, Manuel A. Mohr, Lauren C. Panzera, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map o
Externí odkaz:
https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e
Autor:
Benjamien Moeyaert, Graham Holt, Rajtarun Madangopal, Alberto Perez-Alvarez, Brenna C. Fearey, Nicholas F. Trojanowski, Julia Ledderose, Timothy A. Zolnik, Aniruddha Das, Davina Patel, Timothy A. Brown, Robert N. S. Sachdev, Britta J. Eickholt, Matthew E. Larkum, Gina G. Turrigiano, Hod Dana, Christine E. Gee, Thomas G. Oertner, Bruce T. Hope, Eric R. Schreiter
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Methods to directly label active neurons are still lacking. Here the authors develop CaMPARI2, a photoconvertible fluorescent protein sensor for neuronal activity with improved brightness and calcium binding kinetics, as well as an antibody to amplif
Externí odkaz:
https://doaj.org/article/0bc2383719ed4d3a919e09c4acecd7ca
Autor:
Alberto Perez-Alvarez, Florian Huhn, Céline D. Dürst, Andreas Franzelin, Paul J. Lamothe-Molina, Thomas G. Oertner
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The extensive dendritic arbor of neurons is thought to be actively involved in the processing of information. Dendrites contain a rich diversity of ligand- and voltage-activated ion channels as well as metabotropic receptors. In addition, they are ca
Externí odkaz:
https://doaj.org/article/db0b85dbaab5498280dc3ace0cb30450
Autor:
Alberto Perez-Alvarez, Tim Fieblinger, Thomas Oertner, Paul J. Lamothe-Molina, Christine E. Gee
Publikováno v:
EMBO reports. 23
The striatum is a subcortical brain region responsible for the initiation and termination of voluntary movements. Striatal spiny projection neurons receive major excitatory synaptic input from neocortex and thalamus, and cyclic nucleotides have long
Autor:
Michael B. Hoppa, J. Simon Wiegert, Paul J. Lamothe-Molina, Christine E. Gee, Alberto Perez-Alvarez, Christian Schulze, Brenna C. Fearey, Wei Yang, Ignacio Arganda-Carreras, Ryan J. O’Toole, Lauren C. Panzera, Thomas G. Oertner, Benjamien Moeyaert, Manuel A. Mohr, Eric R. Schreiter
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Information within the brain travels from neuron to neuron across billions of synapses. At any given moment, only a small subset of neurons and synapses are active, but finding the active synapses in brain tissue has been a technical challenge. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ba926600e1c3595ab5511b3b101aef
https://lirias.kuleuven.be/handle/123456789/655313
https://lirias.kuleuven.be/handle/123456789/655313
Autor:
Juan Passas, Almudena Albillos, Nuria García-Magro, Cristina de Castro-Guerín, Sergio Alonso y Gregorio, Jose Carlos Caba-González, Alicia Hernández-Vivanco, Beatriz Carmona-Hidalgo, Alberto Perez-Alvarez, Sara Sanz-Lázaro, Jesús Blázquez, Amanda Jiménez-Pompa, Angel Tabernero, Carmen González-Enguita
Publikováno v:
European Journal of Pharmacology. 796:115-121
The present study was performed to evaluate the Ca v 1 channel subtypes expressed in human chromaffin cells and the role that these channels play in exocytosis and cell excitability. Here we show that human chromaffin cells obtained from organ donors
Autor:
Alberto Perez-Alvarez, Ignacio Arganda-Carreras, Wei Yang, Paul J. Lamothe-Molina, Brenna C. Fearey, Lauren C. Panzera, Manuel A. Mohr, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner, Benjamien Moeyaert, Ryan J. O’Toole
Publikováno v:
bioRxiv
Information within the brain travels from neuron to neuron across synapses. At any given moment, only a few synapses within billions will be active and are thought to transmit key information about the environment, a behavior being executed or memory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeba8922155a6938164b44ca8e6f1c0d
Autor:
Thomas G. Oertner, Alexander Drakew, Matthias Kneussel, Wolfgang Wagner, Anja Konietzny, Michael Frotscher, Jeroen Demmers, Dick H. W. Dekkers, Judit Gonzalez-Gallego, Urban Maier, Alberto Perez-Alvarez, Julia G. Baer, John A. Hammer, Marina Mikhaylova
The spine apparatus (SA) is an endoplasmic reticulum-related organelle which is present in a subset of dendritic spines in cortical and pyramidal neurons. The synaptopodin protein localizes between the stacks of the spine apparatus and is essential f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd07ddb5bfdeadbe7aad40b50e7f85b0
Autor:
Judit Gonzalez-Gallego, Alberto Perez-Alvarez, Jeroen Demmers, Dick H. W. Dekkers, John A. Hammer, Marina Mikhaylova, Wolfgang Wagner, Michael Frotscher, Anja Konietzny, Alexander Drakew, Thomas G. Oertner, Matthias Kneussel, Julia Bär
Publikováno v:
Journal of Cell Science
Journal of Cell Science, 132(16):UNSP jcs230177. Company of Biologists Ltd
Journal of Cell Science, 132(16):UNSP jcs230177. Company of Biologists Ltd
The spine apparatus (SA) is an endoplasmic reticulum-related organelle that is present in a subset of dendritic spines in cortical and pyramidal neurons, and plays an important role in Ca2+ homeostasis and dendritic spine plasticity. The protein syna