Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Alberto Pascual-Montano"'
Autor:
Adrian Garcia-Moreno, Raul López-Domínguez, Juan Antonio Villatoro-García, Alberto Ramirez-Mena, Ernesto Aparicio-Puerta, Michael Hackenberg, Alberto Pascual-Montano, Pedro Carmona-Saez
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 590 (2022)
Statistical methods for enrichment analysis are important tools to extract biological information from omics experiments. Although these methods have been widely used for the analysis of gene and protein lists, the development of high-throughput tech
Externí odkaz:
https://doaj.org/article/b7eda9fce9d8437ab2d5fac54399827f
Autor:
Cristina Gutiérrez-Vázquez, Ana Rodríguez-Galán, Marcos Fernández-Alfara, María Mittelbrunn, Fátima Sánchez-Cabo, Dannys Jorge Martínez-Herrera, Marta Ramírez-Huesca, Alberto Pascual-Montano, Francisco Sánchez-Madrid
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract microRNAs (miRNAs) are tightly regulated during T lymphocyte activation to enable the establishment of precise immune responses. Here, we analyzed the changes of the miRNA profiles of T cells in response to activation by cognate interaction
Externí odkaz:
https://doaj.org/article/c2274d1f5a744b7cac98049a132aa4fe
Autor:
Javed K. Manesia, Zhuofei Xu, Dorien Broekaert, Ruben Boon, Alex van Vliet, Guy Eelen, Thomas Vanwelden, Steve Stegen, Nick Van Gastel, Alberto Pascual-Montano, Sarah-Maria Fendt, Geert Carmeliet, Peter Carmeliet, Satish Khurana, Catherine M. Verfaillie
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 715-721 (2015)
Hematopoietic stem cells (HSCs) in the fetal liver (FL) unlike adult bone marrow (BM) proliferate extensively, posing different metabolic demands. However, metabolic pathways responsible for the production of energy and cellular building blocks in FL
Externí odkaz:
https://doaj.org/article/3cfa86d52a374c13873e5793fdcbdf7e
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178316 (2017)
Benign neurofibromas, the main phenotypic manifestations of the rare neurological disorder neurofibromatosis type 1, degenerate to malignant tumors associated to poor prognosis in about 10% of patients. Despite efforts in the field of (epi)genomics,
Externí odkaz:
https://doaj.org/article/7680558eb7794a788351bcb75c0bf63a
Autor:
Ander Muniategui, Rubén Nogales-Cadenas, Miguél Vázquez, Xabier L Aranguren, Xabier Agirre, Aernout Luttun, Felipe Prosper, Alberto Pascual-Montano, Angel Rubio
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30766 (2012)
miRNAs are small RNA molecules (' 22nt) that interact with their corresponding target mRNAs inhibiting the translation of the mRNA into proteins and cleaving the target mRNA. This second effect diminishes the overall expression of the target mRNA. Se
Externí odkaz:
https://doaj.org/article/2caafa8f3d9849b2a130987011696966
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24289 (2011)
Functional analysis of large sets of genes and proteins is becoming more and more necessary with the increase of experimental biomolecular data at omic-scale. Enrichment analysis is by far the most popular available methodology to derive functional i
Externí odkaz:
https://doaj.org/article/c35bf68e0e3e438bbff83c5f9c6d7345
Autor:
Mateo Paz-Cabezas, Tania Calvo-López, Alejandro Romera-Lopez, Daniel Tabas-Madrid, Jesus Ogando, María-Jesús Fernández-Aceñero, Javier Sastre, Alberto Pascual-Montano, Santos Mañes, Eduardo Díaz-Rubio, Beatriz Perez-Villamil
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5175
Colorectal cancer consensus molecular subtypes (CMSs) are widely accepted and constitutes the basis for patient stratification to improve clinical practice. We aimed to find whether miRNAs could reproduce molecular subtypes, and to identify miRNA tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d1dfc55525a8488e4045f6c1486d5a
http://hdl.handle.net/10261/304530
http://hdl.handle.net/10261/304530
Autor:
Raúl López-Domínguez, Pedro Carmona-Sáez, Michael Hackenberg, Ramirez-Mena A, Ernesto Aparicio-Puerta, Adrian Garcia-Moreno, Alberto Pascual-Montano
GeneCodis is a web-based tool for functional enrichment analysis that allows researchers to integrate different sources of annotations. It extracts sets of significant concurrent annotations and assigns a statistical score to evaluate those that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a2121c27b87185700061e12dfc2d60
https://doi.org/10.1101/2021.04.15.439962
https://doi.org/10.1101/2021.04.15.439962
Autor:
Carlos Alonso-Blanco, F. Xavier Picó, Alberto Pascual-Montano, Arnald Marcer, Detlef Weigel, Belén Méndez-Vigo, Noelia Arteaga, Daniel Tabas-Madrid
Publikováno v:
Plant, Cell & Environment. 41:1806-1820
Current global change is fueling an interest to understand the genetic and molecular mechanisms of plant adaptation to climate. In particular, altered flowering time is a common strategy for escape from unfavourable climate temperature. In order to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6026e3b8a37baa2ae79dc3574801ccc1
https://doi.org/10.1111/pce.13189
https://doi.org/10.1111/pce.13189
Autor:
Daniel, Tabas-Madrid, Belén, Méndez-Vigo, Noelia, Arteaga, Arnald, Marcer, Alberto, Pascual-Montano, Detlef, Weigel, F, Xavier Picó, Carlos, Alonso-Blanco
Publikováno v:
Plant, cellenvironment. 41(8)
Current global change is fueling an interest to understand the genetic and molecular mechanisms of plant adaptation to climate. In particular, altered flowering time is a common strategy for escape from unfavourable climate temperature. In order to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d126756b9a2a155ede97ca32a8db7ecc
https://pubmed.ncbi.nlm.nih.gov/29777598
https://pubmed.ncbi.nlm.nih.gov/29777598