Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Alberto Pérez-Samartín"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cannabidiol (CBD), the main non-psychoactive cannabinoid found in the cannabis plant, elicits several pharmacological effects via the 5-HT1A receptor. The dorsal raphe nucleus (DRN) is the main serotonergic cluster in the brain that expresses the 5-H
Externí odkaz:
https://doaj.org/article/77c4ad1e774d4630b93adf3c248af2d4
Autor:
Ana Palma, Juan Carlos Chara, Alejandro Montilla, Amaia Otxoa-de-Amezaga, Francisca Ruíz-Jaén, Anna M. Planas, Carlos Matute, Alberto Pérez-Samartín, María Domercq
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Abnormalities in myelination are associated to behavioral and cognitive dysfunction in neurodevelopmental psychiatric disorders. Thus, therapies to promote or accelerate myelination could potentially ameliorate symptoms in autism. Clemastine, a hista
Externí odkaz:
https://doaj.org/article/26ccb940dbe84db49fe2734338f9ebc5
Autor:
Ildefonso M. De la Fuente, Carlos Bringas, Iker Malaina, María Fedetz, Jose Carrasco-Pujante, Miguel Morales, Shira Knafo, Luis Martínez, Alberto Pérez-Samartín, José I. López, Gorka Pérez-Yarza, María Dolores Boyano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Associative memory is the main type of learning by which complex organisms respond to certain environmental stimuli. Here, De la Fuente et al. describe a motility pattern consistent with associative conditioned behaviour in unicellular amoebae.
Externí odkaz:
https://doaj.org/article/babfce7a43494c30839614758a942da6
Autor:
Abraham J. Cisneros-Mejorado, Alberto Pérez-Samartín, María Domercq, Rogelio O. Arellano, Miroslav Gottlieb, Friedrich Koch-Nolte, Carlos Matute
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Shortage of oxygen and nutrients in the brain induces the release of glutamate and ATP that can cause excitotoxicity and contribute to neuronal and glial damage. Our understanding of the mechanisms of ATP release and toxicity in cerebrovascular disea
Externí odkaz:
https://doaj.org/article/9660776ba0cc43399a55ce85ed8a997f
Autor:
Oihane Abiega, Sol Beccari, Irune Diaz-Aparicio, Agnes Nadjar, Sophie Layé, Quentin Leyrolle, Diego Gómez-Nicola, María Domercq, Alberto Pérez-Samartín, Víctor Sánchez-Zafra, Iñaki Paris, Jorge Valero, Julie C Savage, Chin-Wai Hui, Marie-Ève Tremblay, Juan J P Deudero, Amy L Brewster, Anne E Anderson, Laura Zaldumbide, Lara Galbarriatu, Ainhoa Marinas, Maria dM Vivanco, Carlos Matute, Mirjana Maletic-Savatic, Juan M Encinas, Amanda Sierra
Publikováno v:
PLoS Biology, Vol 14, Iss 9, p e1002554 (2016)
[This corrects the article DOI: 10.1371/journal.pbio.1002466.].
Externí odkaz:
https://doaj.org/article/d5f7a0d17f3f46ef9920d0f8e6a6c1d7
Autor:
Oihane Abiega, Sol Beccari, Irune Diaz-Aparicio, Agnes Nadjar, Sophie Layé, Quentin Leyrolle, Diego Gómez-Nicola, María Domercq, Alberto Pérez-Samartín, Víctor Sánchez-Zafra, Iñaki Paris, Jorge Valero, Julie C Savage, Chin-Wai Hui, Marie-Ève Tremblay, Juan J P Deudero, Amy L Brewster, Anne E Anderson, Laura Zaldumbide, Lara Galbarriatu, Ainhoa Marinas, Maria dM Vivanco, Carlos Matute, Mirjana Maletic-Savatic, Juan M Encinas, Amanda Sierra
Publikováno v:
PLoS Biology, Vol 14, Iss 5, p e1002466 (2016)
Phagocytosis is essential to maintain tissue homeostasis in a large number of inflammatory and autoimmune diseases, but its role in the diseased brain is poorly explored. Recent findings suggest that in the adult hippocampal neurogenic niche, where t
Externí odkaz:
https://doaj.org/article/a4cb0f67f35446f7a58f2aa586cd812c
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 954-961 (2012)
Overactivation of subtype P2X7 receptors can induce excitotoxic neuronal death by calcium (Ca2+) overload. In this study, we characterize the functional properties of P2X7 receptors using electrophysiology and Ca2+ monitoring in primary cortical neur
Externí odkaz:
https://doaj.org/article/62a97a87b095434b9554d25196bf698a
Autor:
Sarah E. Lutz, Estibaliz González-Fernández, Juan Carlos Chara Ventura, Alberto Pérez-Samartín, Leonid Tarassishin, Hiromitsu Negoro, Naman K. Patel, Sylvia O. Suadicani, Sunhee C. Lee, Carlos Matute, Eliana Scemes
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/d8e7c87c02cc47a0b4b0ae126140d263
Autor:
Sarah E Lutz, Estibaliz González-Fernández, Juan Carlos Chara Ventura, Alberto Pérez-Samartín, Leonid Tarassishin, Hiromitsu Negoro, Naman K Patel, Sylvia O Suadicani, Sunhee C Lee, Carlos Matute, Eliana Scemes
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66657 (2013)
Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. We tested the hypothesis
Externí odkaz:
https://doaj.org/article/bed2e29ae7374fc0a4cdf068daf6cc41
Autor:
Rainald Pablo Ordaz, Rogelio O. Arellano, Abraham Cisneros-Mejorado, Alberto Pérez-Samartín, Edith Garay, Carlos Matute, Agenor Limon, Leticia Robles-Martínez, María Victoria Sánchez-Gómez
Publikováno v:
Molecular Pharmacology. 99:133-146
Oligodendrocytes (OLs) express functional GABAA receptors (GABAARs) that are activated by GABA released at synaptic contacts with axons or by ambient GABA in extrasynaptic domains. In both instances, the receptors' molecular identity has not been ful