Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alberto Nobili"'
Autor:
Tom van den Bergh, Giorgio Tamo, Alberto Nobili, Yifeng Tao, Tianwei Tan, Uwe T Bornscheuer, Remko K P Kuipers, Bas Vroling, René M de Jong, Kalyanasundaram Subramanian, Peter J Schaap, Tom Desmet, Bernd Nidetzky, Gert Vriend, Henk-Jan Joosten
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176427 (2017)
CorNet is a web-based tool for the analysis of co-evolving residue positions in protein super-family sequence alignments. CorNet projects external information such as mutation data extracted from literature on interactively displayed groups of co-evo
Externí odkaz:
https://doaj.org/article/99184a75be76410da58c9c377339d349
Publikováno v:
Journal of cancer immunology. 4(2)
Autor:
Aya Kobayashi, Alberto Nobili, Steven C. Neier, Amissi Sadiki, Robert Distel, Zhaohui Sunny Zhou, Carl D. Novina
Publikováno v:
ChemMedChem. 17
Autor:
Aya Kobayashi, Alberto Nobili, Steven C. Neier, Amissi Sadiki, Robert Distel, Zhaohui Sunny Zhou, Carl D. Novina
Publikováno v:
ChemMedChem. 17(12)
Major challenges to chimeric antigen receptor (CAR) T cell therapies include uncontrolled immune activity, off-tumor toxicities and tumor heterogeneity. To overcome these challenges, we engineered CARs directed against small molecules. By conjugating
Autor:
Moritz, Voss, Chao, Xiang, Jérémy, Esque, Alberto, Nobili, Marian J, Menke, Isabelle, André, Matthias, Höhne, Uwe T, Bornscheuer
Publikováno v:
ACS chemical biology. 15(2)
The enzymatic transamination of ketones into (
Autor:
Isabelle André, Uwe T. Bornscheuer, Matthias Höhne, Moritz Voss, Marian J Menke, Alberto Nobili, Chao Xiang, Jérémy Esque
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2020, 15 (2), pp.416-424. ⟨10.1021/acschembio.9b00888⟩
ACS Chemical Biology, 2020, 15 (2), pp.416-424. ⟨10.1021/acschembio.9b00888⟩
ACS Chemical Biology, American Chemical Society, 2020, 15 (2), pp.416-424. ⟨10.1021/acschembio.9b00888⟩
ACS Chemical Biology, 2020, 15 (2), pp.416-424. ⟨10.1021/acschembio.9b00888⟩
International audience; The enzymatic transamination of ketones into (R)-amines represents an important route for accessing a range of pharmaceuticals or building blocks. Although many publications have dealt with enzyme discovery, protein engineerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d232ba5bfaf0055d0e52ad4c430e679f
https://hal.inrae.fr/hal-02529029/file/acschembio.9b00888_HAL.pdf
https://hal.inrae.fr/hal-02529029/file/acschembio.9b00888_HAL.pdf
Autor:
Henrik Land, Henk-Jan Joosten, Per Berglund, Clare Vickers, Hannes Kohls, Hendrik Mallin, Alberto Nobili, Uwe T. Bornscheuer, Matthias Höhne, Tom van den Bergh, Fabian Steffen-Munsberg, Lilly Skalden
Publikováno v:
Biotechnology Advances. 33:566-604
In this review we analyse structure/sequence-function relationships for the superfamily of PLP-dependent enzymes with special emphasis on class III transaminases. Amine transaminases are highly important for applications in biocatalysis in the synthe
Autor:
Matthias Höhne, Carola Schulzke, Fabian Steffen-Munsberg, Ivan Trentin, Uwe T. Bornscheuer, Hannes Kohls, Alberto Nobili
Publikováno v:
ChemCatChem. 7:757-760
Although the amine transaminase from Vibrio fluvialis has often been applied as a catalyst for the biocatalytic preparation of various chiral primary amines, it is not suitable for the transamination of a-hydroxy ketones and aryl-alkyl ketones bearin
Autor:
Dirk Albrecht, Uwe T. Bornscheuer, Maika Genz, Katharina Riedel, Tom van den Bergh, Henk-Jan Joosten, Alberto Nobili, Anders M. Knight, Ioannis V. Pavlidis
Pyridoxal-5′-phosphate (PLP)-dependent enzymes are ubiquitous in nature and catalyze a variety of important metabolic reactions. The fold-type III PLP-dependent enzyme family is primarily comprised of decarboxylases and alanine racemases. In the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdff11b1298edd95fc69b90a41712412
https://resolver.caltech.edu/CaltechAUTHORS:20161107-083446944
https://resolver.caltech.edu/CaltechAUTHORS:20161107-083446944
Autor:
Susanna Baumeister, Mark W. Kieran, Pratiti Bandopadhayay, Hye-Jung Kim, Carl D. Novina, Karen Wright, Alberto Nobili, Steven C Neier, Colby P Ledoux
Publikováno v:
Neuro-Oncology. 20:i56-i57
INTRODUCTION: T cells play a central role in our immune system’s responses to infections. Recent promising clinical studies have shown that the immune system can be ‘engineered’ to recognize and kill tumor cells by binding to specific proteins