Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alberto Nakauma"'
Autor:
Maud Rijnders, J. Alberto Nakauma-González, Debbie G. J. Robbrecht, Alberto Gil-Jimenez, Hayri E. Balcioglu, Astrid A. M. Oostvogels, Maureen J. B. Aarts, Joost L. Boormans, Paul Hamberg, Michiel S. van der Heijden, Bernadett E. Szabados, Geert J. L. H. van Leenders, Niven Mehra, Jens Voortman, Hans M. Westgeest, Ronald de Wit, Astrid A. M. van der Veldt, Reno Debets, Martijn P. Lolkema
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Immune checkpoint inhibitors (ICI) improve overall survival in patients with metastatic urothelial cancer (mUC), but therapeutic success at the individual patient level varies significantly. Here we identify predictive markers of response, b
Externí odkaz:
https://doaj.org/article/5c826962a5fb45ffbb47fc08f0218098
Autor:
Pauline A. J. Mendelaar, Debbie G. J. Robbrecht, Maud Rijnders, Ronald deWit, Vanja deWeerd, Teoman Deger, Hans M. Westgeest, Maureen J. B. Aarts, Jens Voortman, John W. M. Martens, Astrid A. M. van derVeldt, José Alberto Nakauma‐González, Saskia M. Wilting, Martijn Lolkema
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2086-2097 (2022)
Second‐line treatment with immune checkpoint inhibition in patients with metastatic urothelial cancer (mUC) has a low success rate (~ 20%). Circulating tumour‐derived DNA (ctDNA) levels may guide patient stratification, provided that an affordabl
Externí odkaz:
https://doaj.org/article/697816219cc74830a6f744569b38649b
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Clusters of peripheral blood CD4+ T-cell subsets in mUC patients with and without a tumor response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6781afd5d0f87c357e940606d6d0e6bb
https://doi.org/10.1158/1078-0432.22482042.v1
https://doi.org/10.1158/1078-0432.22482042.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Numbers of major T-cell subsets in peripheral blood and expression of T-cell maturation/activation markers on CD4+ T-cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cf01657b3e9a745096e59a378f8122
https://doi.org/10.1158/1078-0432.22482045
https://doi.org/10.1158/1078-0432.22482045
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e4e3dfd5ed3e6d38d3253f32359e1e
https://doi.org/10.1158/1078-0432.22482048
https://doi.org/10.1158/1078-0432.22482048
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Highlighted immune parameters in blood, plasma and tumor tissue from mUC patients with stable disease as best overall response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b310fb08e7068679564bd8bc7543b59
https://doi.org/10.1158/1078-0432.22482024.v1
https://doi.org/10.1158/1078-0432.22482024.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Transcriptomic analysis of immune cell fractions, T-cell subsets, and chemo-attractants of baseline metastatic tumor biopsies from mUC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177fd0b2e2a90a230208835a42b518b2
https://doi.org/10.1158/1078-0432.22482030.v1
https://doi.org/10.1158/1078-0432.22482030.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Immune parameters in blood, plasma and tumor tissue from mUC patients with stable disease as best overall response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61955b769afb0eab0429ea91f97dad93
https://doi.org/10.1158/1078-0432.22482015
https://doi.org/10.1158/1078-0432.22482015
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Proposed mechanism of action of pembrolizumab in mUC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aec0ef7bfdd6da12e8425e4f2c4f8ed
https://doi.org/10.1158/1078-0432.22482021
https://doi.org/10.1158/1078-0432.22482021
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Correlations between immune parameters in blood, plasma and tumor tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f49aff197745a7668b74223852803b
https://doi.org/10.1158/1078-0432.22482033.v1
https://doi.org/10.1158/1078-0432.22482033.v1