Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Alberto Martínez‐Serrano"'
Autor:
André B. Cunha, Christin Schuelke, Alireza Mesri, Simen K. Ruud, Aleksandra Aizenshtadt, Giorgio Ferrari, Arto Heiskanen, Afia Asif, Stephan S. Keller, Tania Ramos-Moreno, Håvard Kalvøy, Alberto Martínez-Serrano, Stefan Krauss, Jenny Emnéus, Marco Sampietro, Ørjan G. Martinsen
Publikováno v:
Sensors, Vol 24, Iss 2, p 575 (2024)
Implantable cell replacement therapies promise to completely restore the function of neural structures, possibly changing how we currently perceive the onset of neurodegenerative diseases. One of the major clinical hurdles for the routine implementat
Externí odkaz:
https://doaj.org/article/3f9a8c018ef54dbb862e7626f2c1d860
Autor:
Janko Kajtez, Milan Finn Wesseler, Marcella Birtele, Farinaz Riyahi Khorasgani, Daniella Rylander Ottosson, Arto Heiskanen, Tom Kamperman, Jeroen Leijten, Alberto Martínez‐Serrano, Niels B. Larsen, Thomas E. Angelini, Malin Parmar, Johan U. Lind, Jenny Emnéus
Publikováno v:
Advanced Science, Vol 9, Iss 25, Pp n/a-n/a (2022)
Abstract Human in vitro models of neural tissue with tunable microenvironment and defined spatial arrangement are needed to facilitate studies of brain development and disease. Towards this end, embedded printing inside granular gels holds great prom
Externí odkaz:
https://doaj.org/article/0237562c65b34d178bd494d0a00950b1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Parkinson’s disease (PD) is an age-associated neurodegenerative disorder for which there is currently no cure. Cell replacement therapy is a potential treatment for PD; however, this therapy has more clinically beneficial outcomes in younger patien
Externí odkaz:
https://doaj.org/article/1ad7c19d6e8c4b198f975dff62bc8443
Autor:
Janko Kajtez, Sebastian Buchmann, Shashank Vasudevan, Marcella Birtele, Stefano Rocchetti, Christian Jonathan Pless, Arto Heiskanen, Roger A. Barker, Alberto Martínez‐Serrano, Malin Parmar, Johan Ulrik Lind, Jenny Emnéus
Publikováno v:
Advanced Science, Vol 8, Iss 12, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/58f688b32026469cad26ac3313e4567d
Autor:
Janko Kajtez, Sebastian Buchmann, Shashank Vasudevan, Marcella Birtele, Stefano Rocchetti, Christian Jonathan Pless, Arto Heiskanen, Roger A. Barker, Alberto Martínez‐Serrano, Malin Parmar, Johan Ulrik Lind, Jenny Emnéus
Publikováno v:
Advanced Science, Vol 7, Iss 16, Pp n/a-n/a (2020)
Abstract Compartmentalized microfluidic platforms are an invaluable tool in neuroscience research. However, harnessing the full potential of this technology remains hindered by the lack of a simple fabrication approach for the creation of intricate d
Externí odkaz:
https://doaj.org/article/a25dc396c321435dae06dcdeefc39aac
Autor:
Shashank Vasudevan, Janko Kajtez, Ada‐Ioana Bunea, Ana Gonzalez‐Ramos, Tania Ramos‐Moreno, Arto Heiskanen, Merab Kokaia, Niels B. Larsen, Alberto Martínez‐Serrano, Stephan S. Keller, Jenny Emnéus
Publikováno v:
Advanced Science, Vol 6, Iss 24, Pp n/a-n/a (2019)
Abstract In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they
Externí odkaz:
https://doaj.org/article/b178ebee971d45baada0d21c0c6e4ecd
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 1, Pp 49-52 (2016)
Human neural stem cells (hNSCs) derived from the ventral mesencephalon are powerful research tools and candidates for cell therapies in Parkinson′s disease. However, their clinical translation has not been fully realized due, in part, to the limite
Externí odkaz:
https://doaj.org/article/9332e971e12c4951af854f6fe3234329
Autor:
Silvia García-López, Carmen Albo-Castellanos, Rocio G Urdinguio, Susana Cañón, Fátima Sánchez-Cabo, Alberto Martínez-Serrano, Mario F Fraga, Antonio Bernad
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206534 (2018)
BACKGROUND:Human adult adipose-derived stem cells (hADSCs) have become the most promising cell source for regenerative medicine. However the prolonged ex vivo expansion periods required to obtain the necessary therapeutic dose promotes progressive se
Externí odkaz:
https://doaj.org/article/0d37b438f0a448bcb853e833bbcdf058
Autor:
Alberto Martínez-Serrano, Marta P. Pereira, Natalia Avaliani, Anna Nelke, Merab Kokaia, Tania Ramos-Moreno Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Cell replacement therapy in Parkinson's disease (PD) still lacks a study addressing the acquisition of electrophysiological properties of human grafted neural stem cells and their relation with the emergence of behavioral recovery after transplantati
Externí odkaz:
https://doaj.org/article/c58e7737041046deaa7d472e30c8e761
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118499 (2015)
A better understanding of the molecular mechanisms governing stem cell self-renewal will foster the use of different types of stem cells in disease modeling and cell therapy strategies. Immortalization, understood as the capacity for indefinite expan
Externí odkaz:
https://doaj.org/article/f5b73952a3b04766ba10811c57a9a318