Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Alberto Malesci"'
Autor:
Giuseppe Dell’Anna, Ernesto Fasulo, Jacopo Fanizza, Rukaia Barà, Edoardo Vespa, Alberto Barchi, Paolo Cecinato, Lorenzo Fuccio, Vito Annese, Alberto Malesci, Francesco Azzolini, Silvio Danese, Francesco Vito Mandarino
Publikováno v:
Diagnostics, Vol 14, Iss 19, p 2155 (2024)
Zenker’s Diverticulum (ZD) is the most common hypopharyngeal diverticulum; however, it is often underdiagnosed. It results from the herniation of the mucosa and submucosa through Killian’s Triangle. Dysphagia is the primary symptom, occurring in
Externí odkaz:
https://doaj.org/article/d85b7a920613409e87c8541df2dd171f
Autor:
Giulia Rizzo, Federica Rubbino, Sudharshan Elangovan, Giusy Sammarco, Sara Lovisa, Silvia Restelli, Samuel Elias Pineda Chavez, Luca Massimino, Luigi Lamparelli, Marianna Paulis, Annalisa Maroli, Giulia Roda, Mohammad Shalaby, Michele Carvello, Caterina Foppa, Sheona P. Drummond, Paola Spaggiari, Federica Ungaro, Antonino Spinelli, Alberto Malesci, Alessandro Repici, Anthony J. Day, Alessandro Armuzzi, Silvio Danese, Stefania Vetrano
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 741-764 (2023)
Background and Aims: Perianal fistula represents one of the most disabling manifestations of Crohn′s disease (CD) due to complete destruction of the affected mucosa, which is replaced by granulation tissue and associated with changes in tissue orga
Externí odkaz:
https://doaj.org/article/cbfa9700d9e74baa959f2b4dc064fe61
Autor:
Tommaso Cavalleri, Luana Greco, Federica Rubbino, Tsuyoshi Hamada, Maria Quaranta, Fabio Grizzi, Elisabetta Sauta, Vincenzo Craviotto, Paola Bossi, Stefania Vetrano, Lorenza Rimassa, Valter Torri, Riccardo Bellazzi, Alberto Mantovani, Shuji Ogino, Alberto Malesci, Luigi Laghi
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 307-312 (2022)
Abstract Tumor‐associated macrophages (TAMs) have a unique favorable effect on the prognosis of colorectal cancer (CRC), although their association with stage‐specific outcomes remains unclear. We assessed the densities of CD68+ and CD163+ TAMs a
Externí odkaz:
https://doaj.org/article/b585468df1d545b78c2a2c352c3edfd2
Autor:
Federica Rubbino, Valentina Garlatti, Valeria Garzarelli, Luca Massimino, Salvatore Spanò, Paolo Iadarola, Maddalena Cagnone, Martin Giera, Marieke Heijink, Simone Guglielmetti, Vincenzo Arena, Alberto Malesci, Luigi Laghi, Silvio Danese, Stefania Vetrano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract GPR120 (encoded by FFAR4 gene) is a receptor for long chain fatty acids, activated by ω-3 Polyunsaturated Fatty Acids (PUFAs), and expressed in many cell types. Its role in the context of colorectal cancer (CRC) is still puzzling with many
Externí odkaz:
https://doaj.org/article/cc8c0113e4a94069b6883a8cb89ab8fc
Autor:
Laura Bogliolo, Emanuele Cereda, Catherine Klersy, Ludovico De Stefano, Federica Lobascio, Sara Masi, Silvia Crotti, Serena Bugatti, Carlomaurizio Montecucco, Stefania Demontis, Annalisa Mascheroni, Nadia Cerutti, Alberto Malesci, Salvatore Corrao, Riccardo Caccialanza, The NUTRI-COVID19 Collaborative Working Group
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
IntroductionSeveral studies and meta-analyses suggested the role of vitamin D 25OH in preventing severe forms of coronavirus disease 2019 (COVID-19). However, the evidence on the clinical benefits of vitamin D 25OH adequacy in patients hospitalized f
Externí odkaz:
https://doaj.org/article/72a7dcd95c5941b0a377ff8eca955868
Autor:
Luana Greco, Federica Rubbino, Alessandra Morelli, Federica Gaiani, Fabio Grizzi, Gian Luigi de’Angelis, Alberto Malesci, Luigi Laghi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11469 (2021)
Resembling the development of cancer by multistep carcinogenesis, the evolution towards metastasis involves several passages, from local invasion and intravasation, encompassing surviving anoikis into the circulation, landing at distant sites and the
Externí odkaz:
https://doaj.org/article/6255532bcc314e768adcea81bb6e03b1
Autor:
Federica Gaiani, Federica Marchesi, Francesca Negri, Luana Greco, Alberto Malesci, Gian Luigi de’Angelis, Luigi Laghi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5246 (2021)
The review begins with molecular genetics, which hit the field unveiling the involvement of oncogenes and tumor suppressor genes in the pathogenesis of colorectal cancer (CRC) and uncovering genetic predispositions. Then the notion of molecular pheno
Externí odkaz:
https://doaj.org/article/48f991b03acd4a799a592e60b19f499e
Autor:
Luigi Laghi, Francesca Negri, Federica Gaiani, Tommaso Cavalleri, Fabio Grizzi, Gian Luigi de’ Angelis, Alberto Malesci
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9680 (2020)
Understanding molecular features of colon cancer has shed light on its pathogenesis and progression. Over time, some of these features acquired clinical dignity and were incorporated in decision making. Namely, microsatellite instability (MSI) due to
Externí odkaz:
https://doaj.org/article/f6ebbb508cde48f88d2c0cbc7fd5f3bf
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2257 (2020)
Iron is indispensable for cell metabolism of both normal and cancer cells. In the latter, several disruptions of its metabolism occur at the steps of tumor initiation, progression and metastasis. Noticeably, cancer cells require a large amount of iro
Externí odkaz:
https://doaj.org/article/f5be6956e80d43dba60cc95cfbb9ae0c
Autor:
Alberto Malesci, Paolo Bianchi, Giuseppe Celesti, Gianluca Basso, Federica Marchesi, Fabio Grizzi, Giuseppe Di Caro, Tommaso Cavalleri, Lorenza Rimassa, Richard Palmqvist, Alessandro Lugli, Viktor. H. Koelzer, Massimo Roncalli, Alberto Mantovani, Shuji Ogino, Luigi Laghi
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
Tumor-associated macrophages (TAMs) play a role in tumor development and progression. We hypothesized that abundance of TAMs might modify efficacy of 5-fluorouracil chemotherapy in colorectal cancer. We measured the density of CD68+ TAMs at the invas
Externí odkaz:
https://doaj.org/article/b13e6a510a984a278cf744a3e66503b8