Výsledky vyhledávání - "Alberto Lens-Pardo"

Akademický článek

MicroRNA signature and integrative omics analyses define prognostic clusters and key pathways driving prognosis in patients with neuroendocrine neoplasms

Autor: Beatriz Soldevilla, Alberto Lens‐Pardo, Paula Espinosa‐Olarte, Carlos Carretero‐Puche, Sonia Molina‐Pinelo, Carlos Robles, Marta Benavent, Lourdes Gomez‐Izquierdo, Marta Fierro‐Fernández, Patricia Morales‐Burgo, Paula Jimenez‐Fonseca, Beatriz Anton‐Pascual, Yolanda Rodriguez‐Gil, Ana Teijo‐Quintans, Anna La Salvia, Beatriz Rubio‐Cuesta, Maria C. Riesco‐Martínez, Rocio Garcia‐Carbonero

Publikováno v: Molecular Oncology, Vol 17, Iss 4, Pp 582-597 (2023)

Neuroendocrine neoplasms (NENs) are mutationally quiet (low number of mutations/Mb), and epigenetic mechanisms drive their development and progression. We aimed at comprehensively characterising the microRNA (miRNA) profile of NENs, and exploring dow

Externí odkaz: https://doaj.org/article/96f622ea83a04182b9b9cbef9fb1d2ac

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Akademický článek

Integrated miRNA and mRNA expression profiling identifies novel targets and pathological mechanisms in autoimmune thyroid diseases

Autor: Rebeca Martínez-Hernández, Ana Serrano-Somavilla, Ana Ramos-Leví, Miguel Sampedro-Nuñez, Alberto Lens-Pardo, José Luis Muñoz De Nova, Juan Carlos Triviño, María Ujue González, Lorena Torné, Javier Casares-Arias, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid, Mónica Marazuela

Publikováno v: EBioMedicine, Vol 50, Iss , Pp 329-342 (2019)

Background: The mechanisms underlying autoimmune thyroid disease (AITD) remain elusive. Identification of such mechanisms would reveal novel and/or better therapeutic targets. Here, we use integrated analysis of miRNAs and mRNAs expression profiling

Externí odkaz: https://doaj.org/article/09d67af173a4455ba2be8e98d6bd9d03

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Advances in the Treatment of Gastroenteropancreatic Neuroendocrine Carcinomas: Are we Moving Forward?

Autor: Rocio Garcia-Carbonero, Beatriz Anton-Pascual, Andrea Modrego, Maria del Carmen Riesco-Martinez, Alberto Lens-Pardo, Carlos Carretero-Puche, Beatriz Rubio-Cuesta, Beatriz Soldevilla

Publikováno v: Endocrine Reviews.

Poorly differentiated gastroenteropancreatic neuroendocrine carcinomas are aggressive neoplasms of challenging clinical management. A small proportion of patients with early-stage disease may achieve long-term survival, but the majority of patients p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6928677c3a8fd2ffb058959779411f2
https://doi.org/10.1210/endrev/bnad006

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Author response for 'MicroRNA signature and integrative omics analyses define prognostic clusters and key pathways driving prognosis in patients with neuroendocrine neoplasms'

Autor: null Beatriz Soldevilla, null Alberto Lens‐Pardo, null Paula Espinosa‐Olarte, null Carlos Carretero‐Puche, null Sonia Molina‐Pinelo, null Carlos Robles, null Marta Benavent, null Lourdes Gomez‐Izquierdo, null Marta Fierro‐Fernández, null Patricia Morales‐Burgo, null Paula Jimenez‐Fonseca, null Beatriz Anton‐Pascual, null Yolanda Rodriguez‐Gil, null Ana Teijo‐Quintans, null Anna La Salvia, null Beatriz Rubio‐Cuesta, null Maria C Riesco‐Martínez, null Rocio Garcia‐Carbonero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8359ac21c24eb52846b8a77c4fe5705
https://doi.org/10.1002/1878-0261.13393/v2/response1

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Abstract 2289: Comprehensive multiomic analysis reveals different subtypes in neuroendocrine tumors from multiple origins

Autor: Carlos Carretero Puche, Beatriz Soldevilla, Beatriz Gil, Anna La Salvia, Alberto Lens-Pardo, Paula Espinosa, Beatriz Anton-Pascual, Gonzalo Gómez-López, Fátima Al-Shahrour, Rocío García-Carbonero

Publikováno v: Cancer Research. 82:2289-2289

Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with a wide anatomical distribution and different clinical behaviors that share common “neuro” and “endocrine” properties. They are classified in well differentiated G1, G2 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e119f15473dcd1c77c59133eb991c21d
https://doi.org/10.1158/1538-7445.am2022-2289

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Comprehensive Plasma Metabolomic Profile of Patients with Advanced Neuroendocrine Tumors (NETs). Diagnostic and Biological Relevance

Autor: Anna La Salvia, Beatriz Gil-Calderón, Beatriz Rubio-Cuesta, Ángeles López-López, Rocio Garcia-Carbonero, Raúl Rincón, Carlos Carretero-Puche, Beatriz Soldevilla, Alberto Lens-Pardo, P. Espinosa-Olarte, Coral Barbas, Maria C Riesco-Martinez, Ángeles López-Gonzálvez, Jacinto Sarmentero

Publikováno v: Cancers, Vol 13, Iss 2634, p 2634 (2021)
Cancers
Volume 13
Issue 11

Simple Summary Metabolic flexibility is one of the key hallmarks of cancer and metabolites are the final products of this adaptation, reflecting the aberrant changes of tumors. However, the metabolic plasticity of each cancer type is still unknown, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50f9184ca06ca8a8533edc6871671a7
https://www.mdpi.com/2072-6694/13/11/2634

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1158MO Metabolomic profile of advanced neuroendocrine cancer patients

Autor: Ángeles López-Gonzálvez, Rocio Garcia-Carbonero, Carlos Carretero-Puche, A. La Salvia, Ángeles López-López, Maria C Riesco-Martinez, Alberto Lens-Pardo, Coral Barbas, Beatriz Soldevilla, P. Espinosa-Olarte

Publikováno v: Annals of Oncology. 31:S771-S772

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62c04100ac748ede43254000b3129538
https://doi.org/10.1016/j.annonc.2020.08.1371

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1164P Prognostic value of miRNA profiling in neuroendocrine neoplasias (NENs) from lung and gastroenteropancreatic (GEP) origin

Autor: L. Gomez-Izquierdo, Carlos Carretero-Puche, P. Morales-Burgo, M. Fierro-Fernandez, P. Jiménez-Fonseca, Alberto Lens-Pardo, Beatriz Soldevilla, M. Benavent, Rocio Garcia-Carbonero, Sonia Molina-Pinelo, Maria C Riesco-Martinez, A. La Salvia, C. Robles, P. Espinosa-Olarte

Publikováno v: Annals of Oncology. 31:S774-S775

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be3bb06fdeb59e15df25df9d7a466605
https://doi.org/10.1016/j.annonc.2020.08.1377

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Oxidized lipids in the metabolic profiling of neuroendocrine tumors – Analytical challenges and biological implications

Autor: Beatriz Soldevilla, Alberto Lens-Pardo, Coral Barbas, Ángeles López-López, Joanna Godzien, Maria C Riesco-Martinez, Ana Gradillas, Rocio Garcia-Carbonero, Anna La Salvia, Ángeles López-Gonzálvez

Publikováno v: Journal of Chromatography A. 1625:461233

Untargeted metabolomics can be a great tool for exploring new scientific areas; however, wrong metabolite annotation questions the credibility and puts the success of the entire research at risk. Therefore, an effort should be made to improve the qua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b62978b2be7e77e489fea2a97b9279
https://doi.org/10.1016/j.chroma.2020.461233

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