Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Alberto J. Leon"'
Autor:
K. H. Brian Lam, Alberto J. Leon, Weili Hui, Sandy Che-Eun Lee, Ihor Batruch, Kevin Faust, Almos Klekner, Gábor Hutóczki, Marianne Koritzinsky, Maxime Richer, Ugljesa Djuric, Phedias Diamandis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Gioblastoma tumours consist of different niches defined by histology. Here, the authors use proteomics and machine learning to assign protein expression programs to these niches, and reveal that KRAS and hypoxia are associated with drug resistance.
Externí odkaz:
https://doaj.org/article/247ebc3f13744c4b98c1b4e41d550bef
Autor:
Quamrul Huda, David Lyder, Marty Collins, Dave Schroeder, Dan K. Thompson, Ginny Marshall, Alberto J. Leon, Ken Hidalgo, Masum Hossain
Publikováno v:
Fire, Vol 3, Iss 3, p 30 (2020)
Understanding the combustion dynamics of fuels, and the generation and propagation of smoke in a wildland fire, can inform short-range and long-range pollutant transport models, and help address and mitigate air quality concerns in communities. Smold
Externí odkaz:
https://doaj.org/article/6970323bba8f476c9ab78f44aedbb001
Autor:
Anglin Dent, Kevin Faust, K. H. Brian Lam, Narges Alhangari, Alberto J. Leon, Queenie Tsang, Zaid Saeed Kamil, Andrew Gao, Prodipto Pal, Stephanie Lheureux, Amit Oza, Phedias Diamandis
SummaryIntra-tumoral heterogeneity can wreak havoc on current precision medicine strategies due to challenges in sufficient sampling of geographically separated areas of biodiversity distributed across centimeter-scale tumor distances. In particular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d314eaa14b4dca7dafb6a85b8085f25a
https://doi.org/10.1101/2023.01.11.22283903
https://doi.org/10.1101/2023.01.11.22283903
Publikováno v:
Cancer Research. 82:1685-1685
BACKGROUND: Emerging evidence strongly implicates intra-tumoral heterogeneous biology in treatment resistance and disease progression across many cancer types. Thus, there is a need for workflows capable of systematically resolving and targeting dist
Autor:
K. H. Brian Lam, Alberto J. Leon, Weili Hui, Sandy Che-Eun Lee, Ihor Batruch, Kevin Faust, Almos Klekner, Gábor Hutóczki, Marianne Koritzinsky, Maxime Richer, Ugljesa Djuric, Phedias Diamandis
Publikováno v:
Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-tumoral heterogeneity implicated in treatment resistance and progression. While regional and single cell transcriptomic variations of glioblastoma have been re
Autor:
Ginny Marshall, Dan K. Thompson, Masum Hossain, Quamrul Huda, Ken Hidalgo, David Lyder, Alberto J. Leon, Dave Schroeder, Marty Collins
Publikováno v:
Fire, Vol 3, Iss 30, p 30 (2020)
Fire
Volume 3
Issue 3
Fire
Volume 3
Issue 3
Understanding the combustion dynamics of fuels, and the generation and propagation of smoke in a wildland fire, can inform short-range and long-range pollutant transport models, and help address and mitigate air quality concerns in communities. Smold
Autor:
Adnan Khan, Hongxia Chen, Jun Wang, Stéphane G. Paquette, Alyson A. Kelvin, Linxi Huang, Huanjie Ma, Xibing Fang, Nanlan Zheng, Weidong Liu, Amber Farooqui, Jesus F. Bermejo-Martin, Yingmu Cai, Kezhao Hu, Sheng Xu, Chunnuan Lin, Li Zhang, Pengzhou Lin, Zhijian Zhu, Renhua Wu, Weihong Chen, David J. Kelvin, Suwu Wu, Alberto J. Leon, Tiansheng Zeng, Peng Sun, Xiuming Wu, Zhancheng Yao, Yisu Liu
Publikováno v:
New England Journal of Medicine. 374:596-598
This report shows evidence for nosocomial transmission of H7N9 influenza from a patient to two physicians who provided care.
Autor:
Stephen S. H. Huang, David J. Kelvin, Stéphane G. Paquette, Alyson A. Kelvin, Alberto J. Leon, David Banner
Publikováno v:
The Journal of General Virology
Influenza B viruses have become increasingly more prominent during influenza seasons. Influenza B infection is typically considered a mild disease and receives less attention than influenza A, but has been causing 20 to 50 % of the total influenza in
Autor:
Alyson A. Kelvin, Stephen S. H. Huang, Barry B. Rubin, Thirumagal Kanagasabai, Stéphane G. Paquette, Yuan Fang, David J. Kelvin, David Banner, Louling Xu, Salvatore Rubino, Norbert Degousee, Alberto J. Leon
Publikováno v:
Journal of Virology
Young children are typically considered a high-risk group for disease associated with influenza virus infection. Interestingly, recent clinical reports suggested that young children were the smallest group of cases with severe pandemic 2009 H1N1 (H1N
Publikováno v:
The New England journal of medicine. 375(10)