Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Alberto J L Macario"'
Autor:
Silvia Vilasi, Rita Carrotta, Maria Rosalia Mangione, Claudia Campanella, Fabio Librizzi, Loredana Randazzo, Vincenzo Martorana, Antonella Marino Gammazza, Maria Grazia Ortore, Annalisa Vilasi, Gabriella Pocsfalvi, Giosalba Burgio, Davide Corona, Antonio Palumbo Piccionello, Giovanni Zummo, Donatella Bulone, Everly Conway de Macario, Alberto J L Macario, Pier Luigi San Biagio, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97657 (2014)
It has been established that Hsp60 can accumulate in the cytosol in various pathological conditions, including cancer and chronic inflammatory diseases. Part or all of the cytosolic Hsp60 could be naïve, namely, bear the mitochondrial import signal
Externí odkaz:
https://doaj.org/article/8ee4bc6c32134030a3350365e267331b
Autor:
Giuseppa D’Amico, Radha Santonocito, Godfrey Grech, Giuseppa Graceffa, Calogero Cipolla, Federica Scalia, Samuele Raccosta, Mauro Manno, Everly Conway de Macario, Alberto J. L. Macario, Francesco Cappello, Francesca Rappa, Celeste Caruso Bavisotto, Claudia Campanella
Publikováno v:
Biology, Vol 13, Iss 9, p 743 (2024)
Background: The incidence of various types of cancer, for example, papillary thyroid carcinoma (PTC), is on the rise. Since therapeutic success depends greatly on early diagnosis, reliable diagnostic biomarkers must be identified, and easy-to-apply t
Externí odkaz:
https://doaj.org/article/11d8219f73944c1fa34e59a432591f56
Autor:
Claudia Campanella, Fabio Bucchieri, Anna M Merendino, Alberto Fucarino, Giosalba Burgio, Davide F V Corona, Giovanna Barbieri, Sabrina David, Felicia Farina, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42008 (2012)
BACKGROUND: In a previous work we showed for the first time that human tumor cells secrete Hsp60 via exosomes, which are considered immunologically active microvesicles involved in tumor progression. This finding raised questions concerning the route
Externí odkaz:
https://doaj.org/article/93f36aaee75f436ca2aae23576f7d0ed
Autor:
Francesco Cappello, Gaetano Caramori, Claudia Campanella, Chiara Vicari, Isabella Gnemmi, Andrea Zanini, Antonio Spanevello, Armando Capelli, Giampiero La Rocca, Rita Anzalone, Fabio Bucchieri, Silvestro Ennio D'Anna, Fabio L M Ricciardolo, Paola Brun, Bruno Balbi, Mauro Carone, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Antonino Di Stefano
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e28200 (2011)
BackgroundIt is increasingly clear that some heat shock proteins (Hsps) play a role in inflammation. Here, we report results showing participation of Hsp60 in the pathogenesis of chronic obstructive pulmonary diseases (COPD), as indicated by data fro
Externí odkaz:
https://doaj.org/article/17adeac62af342d3ae37bd8812d2dade
Autor:
Anna M Merendino, Fabio Bucchieri, Claudia Campanella, Vito Marcianò, Anna Ribbene, Sabrina David, Giovanni Zummo, Giosalba Burgio, Davide F V Corona, Everly Conway de Macario, Alberto J L Macario, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9247 (2010)
Hsp60, a Group I mitochondrial chaperonin, is classically considered an intracellular chaperone with residence in the mitochondria; nonetheless, in the last few years it has been found extracellularly as well as in the cell membrane. Important questi
Externí odkaz:
https://doaj.org/article/5a5c169e599749fc81920d472e6c47c6
Autor:
Francesco Cappello, Everly Conway de Macario, Valentina Di Felice, Giovanni Zummo, Alberto J L Macario
Publikováno v:
PLoS Pathogens, Vol 5, Iss 8, p e1000552 (2009)
Chlamydia trachomatis (CT) infection is one of the most common causes of reproductive tract diseases and infertility. CT-Hsp60 is synthesized during infection and is released in the bloodstream. As a consequence, immune cells will produce anti-CT-Hsp
Externí odkaz:
https://doaj.org/article/56bf6237a0124f778d95d435314be999
Autor:
Charbel A. Basset, Inaya Hajj Hussein, Abdo R. Jurjus, Francesco Cappello, Everly Conway de Macario, Alberto J. L. Macario, Angelo Leone
Publikováno v:
Applied Biosciences, Vol 2, Iss 4, Pp 607-616 (2023)
The chaperone system (CS) is emerging as a key multistage participant in carcinogenesis. The CS chief components are the molecular chaperones (some of which are named heat shock proteins or Hsp), which are typically cytoprotective but if abnormal in
Externí odkaz:
https://doaj.org/article/90adff64b78b468a8aa2dff30115eb3a
Autor:
Leila Noori, Vahid Saqagandomabadi, Valentina Di Felice, Sabrina David, Celeste Caruso Bavisotto, Fabio Bucchieri, Francesco Cappello, Everly Conway de Macario, Alberto J. L. Macario, Federica Scalia
Publikováno v:
Cells, Vol 13, Iss 3, p 217 (2024)
The putative pathogenic roles and therapeutic potential of the chaperone system (CS) in amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are reviewed to provide a bibliographic and conceptual platform for launching research on the diag
Externí odkaz:
https://doaj.org/article/45e2a572e6844b43bb791f1b6cbbab34
Autor:
Letizia Paladino, Francesca Rappa, Rosario Barone, Filippo Macaluso, Francesco Paolo Zummo, Sabrina David, Marta Anna Szychlinska, Fabio Bucchieri, Everly Conway de Macario, Alberto J. L. Macario, Francesco Cappello, Antonella Marino Gammazza
Publikováno v:
Biology, Vol 12, Iss 11, p 1394 (2023)
Probiotics are live microorganisms that yield health benefits when consumed, generally by improving or restoring the intestinal flora (microbiota) as part of the muco-microbiotic layer of the bowel. In this work, mice were fed with ethanol alone or i
Externí odkaz:
https://doaj.org/article/2ab33950ab874359b77ffc9aa1916d1c
Autor:
Federica Scalia, Everly Conway de Macario, Giuseppe Bonaventura, Francesco Cappello, Alberto J. L. Macario
Publikováno v:
Biology, Vol 12, Iss 5, p 641 (2023)
Genetic chaperonopathies are rare but, because of misdiagnosis, there are probably more cases than those that are recorded in the literature and databases. This occurs because practitioners are generally unaware of the existence and/or the symptoms a
Externí odkaz:
https://doaj.org/article/1ca4a0982f5c47229e61efc5a8e6a408