Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alberto García-Mariscal"'
Autor:
Carmen Rodriguez-Cupello, Monica Dam, Laura Serini, Shan Wang, David Lindgren, Emelie Englund, Pontus Kjellman, Håkan Axelson, Alberto García-Mariscal, Chris D. Madsen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The STRIPAK complex has been linked to a variety of biological processes taking place during embryogenesis and development, but its role in cancer has only just started to be defined. Here, we expand on previous work indicating a role for the scaffol
Externí odkaz:
https://doaj.org/article/e069d909a6e749478abe8f3b7ee5b908
Autor:
Jolanda van Hengel, Alberto García-Mariscal, Astrid L. Basse, Cord Brakebusch, Karine Peyrollier, Esben Pedersen, Ralph Rühl
Publikováno v:
Small GTPases. 9:433-444
The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Usi
Autor:
Cristina Hernández-Munain, Vanina García, Jennifer López-Ros, Koichi Ikuta, Alonso Rodríguez-Caparrós, Áurea Casal, Shizue Tani-ichi, Alberto García-Mariscal
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Tcrd and Tcrg display identical developmental programs that depend on the activity of the enhancers E delta and E gamma being "on" in pre-beta-selection thymocytes to activate transcription and V(D) J recombination of the unrearranged genes and "off"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d75037c422544a721ef6dad9f157aa
http://hdl.handle.net/10261/183694
http://hdl.handle.net/10261/183694
Publikováno v:
Inmunología. 32:57-69
Resumen La recombinacion V(D)J consiste en el ensamblaje de los segmentos genicos presentes en los genes de las cadenas variables de los receptores de antigeno para generar la diversidad del reconocimiento antigenico en linfocitos. El conocimiento de
Publikováno v:
The Journal of Immunology. 188:3278-3293
The Tcra enhancer (Eα) is essential for pre-TCR–mediated activation of germline transcription and V(D)J recombination. Eα is considered an archetypical enhanceosome that acts through the functional synergy and cooperative binding of multiple tran