Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Alberto Donfrancesco"'
Autor:
Laura Fontana, Micol E Fiori, Sonia Albini, Loredana Cifaldi, Serena Giovinazzi, Matteo Forloni, Renata Boldrini, Alberto Donfrancesco, Valentina Federici, Patrizio Giacomini, Cesare Peschle, Doriana Fruci
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2236 (2008)
We identified a key oncogenic pathway underlying neuroblastoma progression: specifically, MYCN, expressed at elevated level, transactivates the miRNA 17-5p-92 cluster, which inhibits p21 and BIM translation by interaction with their mRNA 3' UTRs. Ove
Externí odkaz:
https://doaj.org/article/437f2f409d9c42eeb5fcacc071668e90
Autor:
Alessandro Jenkner, Aurora Castellano, Heather P. McDowell, Alberto Donfrancesco, Ilaria Ilari, Maria Debora De Pasquale, Carlo Dominici, Clementina De Laurentis, Maria Antonietta De Ioris, Samantha Cialfi
Publikováno v:
Pediatric Blood & Cancer. 54:55-61
Aim Activity and toxiciy of gefitinib in combination with topotecan and cyclophosphamide (CPA) were evaluated in a case-series of relapsed neuroblastoma (NB) patients. The in vitro activity of the combination was also assessed. Procedure Gefitinib (2
Autor:
Maria Luisa Garrè, P. Fidani, Raffaele Cozza, Annalisa Serra, Renata Boldrini, Alberto Donfrancesco, Maria Antonietta De Ioris, Ilaria Ilari, Luigi De Sio, Giuseppe Milano
Publikováno v:
Journal of Neuro-Oncology. 92:177-183
Purpose Atypical Teratoid/Rhabdoid Tumour is a rare and aggressive childhood tumour. The outcome of a series treated with the same multimodal strategy was reported. Patients The patients were treated with surgery, 2 courses of ifosfamide/carboplatin/
Autor:
Milena Calderone, Gianni Bisogno, Costanza De Rossi, Alberto Donfrancesco, Giovanni Cecchetto, Modesto Carli, Sandro Dallorso, Andrea Ferrari, Yessika Gamboa, Guido Sotti, Lorenza Gandola, Angelo Rosolen
Publikováno v:
Pediatric Blood & Cancer. 50:1154-1158
Background Parameningeal rhabdomyosarcoma (PM-RMS) is a rare, highly malignant pediatric tumor arising from locations adjacent to the meninges, from where it can spread intracranially. Procedure We reviewed 109 children with non-metastatic PM-RMS enr
Autor:
Maria Antonietta De Ioris, Alessandro Jenkner, Giuseppe Milano, Alberto Donfrancesco, Ilaria Ilari, Aurora Castellano, Carlo Dominici, Clementina De Laurentis, Maria Carmen Garganese
Publikováno v:
Journal of Pediatric Hematology/Oncology. 29:799-803
A girl with metastatic neuroblastoma diagnosed at 4 years of age experienced an early disseminated relapse after high-dose chemotherapy. After reinduction, compassionate treatment with gefitinib (250 mg/d fixed dose) with oral topotecan (0.8 mg/m(2)/
Autor:
Renata Boldrini, Alberto Donfrancesco, Francesco Massimo Perla, George Kokai, Carlo Dominici, Stefania Uccini, Maria Rita Nicotra, Pier Giorgio Natali, Pierluigi Altavista, Cristina Colarossi, Carlo Cappelli, Denis A. Cozzi, Paul D. Losty, Stefania Scarpino, C. Boglino, Olga Mannarino, Heather P. McDowell
Publikováno v:
British Journal of Cancer
British Journal of Cancer 1 (2006): 49–55.
info:cnr-pdr/source/autori:Uccini S, Colarossi C, Scarpino S, Boldrini R, Natali PG, Nicotra MR, Perla FM, Mannarino O, Altavista P, Boglino C, Cappelli CA, Cozzi D, Donfrancesco A, Kokai G, Losty PD, McDowell HP, Dominici C./titolo:Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours./doi:/rivista:British Journal of Cancer/anno:2006/pagina_da:49/pagina_a:55/intervallo_pagine:49–55/volume:1
British Journal of Cancer 1 (2006): 49–55.
info:cnr-pdr/source/autori:Uccini S, Colarossi C, Scarpino S, Boldrini R, Natali PG, Nicotra MR, Perla FM, Mannarino O, Altavista P, Boglino C, Cappelli CA, Cozzi D, Donfrancesco A, Kokai G, Losty PD, McDowell HP, Dominici C./titolo:Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours./doi:/rivista:British Journal of Cancer/anno:2006/pagina_da:49/pagina_a:55/intervallo_pagine:49–55/volume:1
Multiple defects in apoptotic pathways have been described in peripheral neuroblastic tumours (NTs). Mitosis-karyorrhexis index (MKI) is a reliable morphological marker identifying favourable and unfavourable NTs. The extent to which apoptotic proces
Autor:
Alessandro Jenkner, Alberto Donfrancesco, Giuseppe Milano, Carlo Dominici, Aurora Castellano, P. Fidani, L. De Sio
Publikováno v:
Pediatric Blood & Cancer. 47:30-36
Purpose We report the off-label study aimed at investigating the use of temozolomide (TMZ) as single agent in relapsed or resistant pediatric solid tumors. The drug was administered at the dose of 215 mg/m2/day × 5 days or 180 mg/m2/day × 5 days in
Autor:
Carlo Dominici, Giuseppe Milano, Raffaele Cozza, Olga Mannarino, Alessandro Inserra, Heather P. McDowell, Renata Boldrini, Alberto Donfrancesco, Pierluigi Altavista, Anna Clerico
Publikováno v:
European Journal of Cancer. 41:2288-2296
Identification of patients with a poor prognosis for non-metastatic rhabdomyosarcoma (RMS) remains a clinical challenge. Prospective analysis for the presence of disseminated RMS cells in bone marrow at diagnosis, using immunocytochemistry, with MyoD
Autor:
Alessandro Inserra, Paola Francalanci, Alessandro Jenkner, Francesco Callea, Rita Devito, Francesca Diomedi-Camassei, C. Boglino, Renata Boldrini, Alberto Donfrancesco
Publikováno v:
Ultrastructural Pathology. 29:493-501
Pulmonary blastomas are rare neoplasms typically occurring in patients of pediatric age, clinically characterized by fever, respiratory distress, and radiologic findings of a pulmonary cystic and/or solid mass with partial or complete obliteration of
Autor:
Raffaele Cozza, L. De Sio, Ilaria Ilari, Alessandro Jenkner, C. De Laurentis, Alberto Donfrancesco, Alessandro Inserra, Giuseppe Milano, Aurora Castellano, P. Fidani, Carlo Dominici, Giovanni Deb
Publikováno v:
Scopus-Elsevier
Children affected by advanced neuroblastoma have a discouraging prognosis, but intensive induction chemotherapy may increase the complete response rate. The combination of ifosfamide, carboplatin and etoposide (ICE) was used for the first time as fro