Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alberto De La Iglesia"'
Autor:
Marta Illescas-López, Lucía Chaves-Blanco, Adolfo de Salazar, Melisa Hernández-Febles, Raquel Carracedo, Eduardo Lagarejos, Ana Fuentes, Sara Pereira, Maria Cea, Alberto De La Iglesia, Carolina Freyre, Asunción Iborra, Valle Odero, Aurora García-Barrionuevo, Antonio Aguilera, María José Pena, Federico García
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectivesPrecise HDV-RNA detection and quantification are pivotal for diagnosis and monitoring of response to newly approved treatment. We evaluate the performance of three HDV RNA detection and quantification assays.MethodsHepatitis Delta RT-PCR sy
Externí odkaz:
https://doaj.org/article/f9bd314f0dd942fb973669a0ec7444a5
Autor:
Daniel Marcu, Dorte L. Egeberg, Guillaume Richer, Brendan Houston, Emily Delgouffe, Gülizar Saritas, Omar Ammar, Lydia Wehrli, Cyril Djari, Alberto de la Iglesia
Publikováno v:
Biology Open, Vol 13, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/a812626069f34a7fa368cfb8f2770c7b
Autor:
Daniel Marcu, Dorte Egeberg, Guillaume Richer, Manon Oud, Brendan Houston, Sven Berres, Alberto de la Iglesia
Publikováno v:
Biology Open, Vol 12, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/c858e3a41ba4456ca5e03a93cba726a5
Autor:
Anita Y.M. Howe, Chaturaka Rodrigo, Evan B. Cunningham, Mark W. Douglas, Julia Dietz, Jason Grebely, Stephanie Popping, Javier Alejandro Sfalcin, Milosz Parczewski, Christoph Sarrazin, Adolfo de Salazar, Ana Fuentes, Murat Sayan, Josep Quer, Midori Kjellin, Hege Kileng, Orna Mor, Johan Lennerstrand, Slim Fourati, Velia Chiara Di Maio, Vladimir Chulanov, Jean-Michel Pawlotsky, P. Richard Harrigan, Francesca Ceccherini-Silberstein, Federico Garcia, Marianne Martinello, Gail Matthews, Fay Fabián Fernando, Juan I. Esteban, Beat Müllhaupt, Julian Schulze zur Wiesch, Peter Buggisch, Christoph Neumann-Haefelin, Thomas Berg, Christoph P. Berg, Jörn M. Schattenberg, Christophe Moreno, Rudolf Stauber, Andrew Lloyd, Gregory Dore, Tanya Applegate, Juan Ignacio, Damir Garcia-Cehic, Josep Gregori, Francisco Rodriguez-Frias, Ariadna Rando, Yael Gozlan, Mario Angelico, Massimo Andreoni, Sergio Babudieri, Ada Bertoli, Valeria Cento, Nicola Coppola, Antonio Craxì, Stefania Paolucci, Giustino Parruti, Caterina Pasquazzi, Carlo Federico Perno, Elisabetta Teti, C. Vironet, Anders Lannergård, Ann-Sofi Duberg, Soo Aleman, Tore Gutteberg, Alexandre Soulier, Aurélie Gourgeon, Stephane Chevaliez, Stanislas Pol, Fabrice Carrat, Dominique Salmon, Rolf Kaiser, Elena Knopes, Perpetua Gomes, Rob de Kneght, Bart Rijnders, Mario Poljak, Maja Lunar, Rafael Usubillaga, Carole Seguin_Devaux, Enoch Tay, Caroline Wilson, Dao Sen Wang, Jacob George, Jen Kok, Ana Belén Pérez, Natalia Chueca, Miguel García-Deltoro, Ana María Martínez-Sapiña, María Magdalena Lara-Pérez, Silvia García-Bujalance, Teresa Aldámiz-Echevarría, Francisco Jesús Vera-Méndez, Juan Antonio Pineda, Marta Casado, Juan Manuel Pascasio, Javier Salmerón, Juan Carlos Alados-Arboledas, Antonio Poyato, Francisco Téllez, Antonio Rivero-Juárez, Dolores Merino, María Jesús Vivancos-Gallego, José Miguel Rosales-Zábal, María Dolores Ocete, Miguel Ángel Simón, Pilar Rincón, Sergi Reus, Alberto De la Iglesia, Isabel García-Arata, Miguel Jiménez, Fernando Jiménez, José Hernández-Quero, Carlos Galera, Mohamed Omar Balghata, Joaquín Primo, Mar Masiá, Nuria Espinosa, Marcial Delgado, Miguel Ángel von-Wichmann, Antonio Collado, Jesús Santos, Carlos Mínguez, Felícitas Díaz-Flores, Elisa Fernández, Enrique Bernal, José De Juan, José Joaquín Antón, Mónica Vélez, Antonio Aguilera, Daniel Navarro, Juan Ignacio Arenas, Clotilde Fernández, María Dolores Espinosa, María José Ríos, Roberto Alonso, Carmen Hidalgo, Rosario Hernández, María Jesús Téllez, Francisco Javier Rodríguez, Pedro Antequera, Cristina Delgado, Patricia Martín, Javier Crespo, Berta Becerril, Oscar Pérez, Antonio García-Herola, José Montero, Carolina Freyre, Concepción Grau, Joaquin Cabezas, Miguel Jimenez, Manuel Alberto Macias Rodriguez, Cristina Quilez, Maria Rodriguez Pardo, Leopoldo Muñoz-Medina, Blanca Figueruela
Publikováno v:
JHEP Reports, Vol 4, Iss 5, Pp 100462- (2022)
Background & Aims: Direct-acting antiviral (DAA) regimens provide a cure in >95% of patients with chronic HCV infection. However, in some patients in whom therapy fails, resistance-associated substitutions (RASs) can develop, limiting retreatment opt
Externí odkaz:
https://doaj.org/article/f2e6a1ce74794d3c98e6f58a4144688c
Autor:
Alberto de la Iglesia, Paula Jauregi, Meritxell Jodar, Ferran Barrachina, Lukas Ded, Carme Mallofré, Leonardo Rodríguez-Carunchio, Juan Manuel Corral, Josep Lluís Ballescà, Katerina Komrskova, Judit Castillo, Rafael Oliva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12398 (2022)
Male germ cells experience a drastic chromatin remodeling through the nucleo-histone to nucleo-protamine (NH-NP) transition necessary for proper sperm functionality. Post-translational modifications (PTMs) of H4 Lys5, such as acetylation (H4K5ac), pl
Externí odkaz:
https://doaj.org/article/d54c1e11d2a94508af96f564b9f80f08
Autor:
Gianluca Arauz-Garofalo, Meritxell Jodar, Mar Vilanova, Alberto de la Iglesia Rodriguez, Judit Castillo, Ada Soler-Ventura, Rafael Oliva, Marta Vilaseca, Marina Gay
Publikováno v:
Proteomes, Vol 9, Iss 2, p 21 (2021)
Protamines replace histones as the main nuclear protein in the sperm cells of many species and play a crucial role in compacting the paternal genome. Human spermatozoa contain protamine 1 (P1) and the family of protamine 2 (P2) proteins. Alterations
Externí odkaz:
https://doaj.org/article/d2be6813e3894bb785979a9194c49962
Autor:
Alba M. G. Blazquez, Rocio I. R. Macias, Candela Cives-Losada, Alberto de la Iglesia, Jose J. G. Marin, Maria J. Monte
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Transporters involved in bile acid (BA) handling by the mammary gland are poorly understood. Here we have investigated the role of ABC proteins in blood-milk BA traffic and its sensitivity to maternal cholestasis. BA concentrations in rat an
Externí odkaz:
https://doaj.org/article/7420089d0fcb4fc2bbcafa376e74fce2
Autor:
Ana Belén Pérez, Natalia Chueca, Juan Macías, Juan Antonio Pineda, Javier Salmerón, Antonio Rivero-Juárez, Carmen Hidalgo-Tenorio, María Dolores Espinosa, Francisco Téllez, Miguel Ángel Von-Wichmann, Mohamed Omar, Jesús Santos, José Hernández-Quero, José Joaquin Antón, Antonio Collado, Ana Belén Lozano, Miguel García-Deltoro, Marta Casado, Juan Manuel Pascasio, Aida Selfa, José Miguel Rosales, Alberto De la Iglesia, Juan Ignacio Arenas, Silvia García-Bujalance, María José Ríos, Enrique Bernal, Onofre Martínez, Antonio García-Herola, Mónica Vélez, Pilar Rincón, Federico García
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221231 (2019)
Treatment guidelines differ in their recommendation to determine baseline resistance associated substitutions (RAS) before starting a first-line treatment with direct-acting antivirals (DAAs). Here we analyze the efficacy of DAA treatment with baseli
Externí odkaz:
https://doaj.org/article/772af61f55174fca9fb2de6905d5ba87
Autor:
Mélina Blanco, Laila El Khattabi, Clara Gobé, Marion Crespo, Manon Coulée, Alberto de la Iglesia, Côme Ialy‐Radio, Clementine Lapoujade, Maëlle Givelet, Marion Delessard, Ivan Seller‐Corona, Kosuke Yamaguchi, Nadège Vernet, Fred Van Leeuwen, Alban Lermine, Yuki Okada, Romain Daveau, Rafael Oliva, Pierre Fouchet, Ahmed Ziyyat, Delphine Pflieger, Julie Cocquet
Publikováno v:
EMBO reports. Wiley-Blackwell
Spermatozoa have a unique genome organization: their chromatin is almost completely devoid of histones and is formed instead of protamines which confer a high level of compaction and preserve paternal genome integrity until fertilization. Histone-to-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19bdf24b3f9ddcd005b29ed4b2feb9c
https://doi.org/10.1101/2022.10.17.512530
https://doi.org/10.1101/2022.10.17.512530
Publikováno v:
WIREs Mechanisms of Disease. 15
Male germ cells undergo an extreme but fascinating process of chromatin remodeling that begins in the testis during the last phase of spermatogenesis and continues through epididymal sperm maturation. Most of the histones are replaced by small protei