Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alberto Cebrian-Serrano"'
Autor:
Katrin Meindl, Naomi Issler, Sara Afonso, Alberto Cebrian-Serrano, Karin Müller, Christina Sterner, Helga Othmen, Ines Tegtmeier, Ralph Witzgall, Enriko Klootwijk, Benjamin Davies, Robert Kleta, Richard Warth
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Normal function of the C-terminal Eps15 homology domain-containing protein 1 (EHD1) has previously been associated with endocytic vesicle trafficking, shaping of intracellular membranes, and ciliogenesis. We recently identified an autosomal recessive
Externí odkaz:
https://doaj.org/article/fd42d22c6ae24e04acdfb7eeea4fccc3
Autor:
Sara Bilekova, Balma Garcia-Colomer, Alberto Cebrian-Serrano, Silvia Schirge, Karsten Krey, Michael Sterr, Thomas Kurth, Stefanie M. Hauck, Heiko Lickert
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Spermatogenesis is a crucial biological process that enables the production of functional sperm, allowing for successful reproduction. Proper germ cell differentiation and maturation require tight regulation of hormonal signals, cellular signaling pa
Externí odkaz:
https://doaj.org/article/ac8295137f8d4db294126b3a8c96bf4e
Autor:
Rose Hodgson, Xijin Xu, Consuelo Anzilotti, Mukta Deobagkar-Lele, Tanya L. Crockford, Jessica D. Kepple, Eleanor Cawthorne, Aneesha Bhandari, Alberto Cebrian-Serrano, Martin J. Wilcock, Benjamin Davies, Richard J. Cornall, Katherine R. Bull
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Despite an upregulation in anergic B cells, N-myc downstream-regulated gene 1 (NDRG1) is not required for the tolerogenic downstream responses, reducing risk of immune modulation on targeting of NDRG1 for cancer therapeutics.
Externí odkaz:
https://doaj.org/article/071960c232c647ea9fe3a78b10f61494
Autor:
Alexandros A. Pittis, Valerie Goh, Alberto Cebrian-Serrano, Jennifer Wettmarshausen, Fabiana Perocchi, Toni Gabaldón
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The mitochondrial calcium uptake system, crucial for cellular processes, evolved in ancient eukaryotes. Here, authors perform a phylogenomic analysis across 1,156 eukaryotes, and show that previously identified animal and fungal genes in this system
Externí odkaz:
https://doaj.org/article/be276a83a522423db2f562d273d11d58
Autor:
Alberto Cebrian-Serrano, Shijun Zha, Lars Hanssen, Daniel Biggs, Christopher Preece, Benjamin Davies
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169887 (2017)
Genome manipulation in the mouse via microinjection of CRISPR/Cas9 site-specific nucleases has allowed the production time for genetically modified mouse models to be significantly reduced. Successful genome manipulation in the mouse has already been
Externí odkaz:
https://doaj.org/article/616fd699410446b8b89450017541961d
Autor:
Ismael González-García, Elena García-Clavé, Alberto Cebrian-Serrano, Ophélia Le Thuc, Raian E. Contreras, Yanjun Xu, Tim Gruber, Sonja C. Schriever, Beata Legutko, Jutta Lintelmann, Jerzy Adamski, Wolfgang Wurst, Timo D. Müller, Stephen C. Woods, Paul T. Pfluger, Matthias H. Tschöp, Alexandre Fisette, Cristina García-Cáceres
Publikováno v:
Cell metabolism 35(3), 438-455.e7 (2023). doi:10.1016/j.cmet.2023.02.004
Until menopause, women have a lower propensity to develop metabolic diseases than men, suggestive of a protective role for sex hormones. Although a functional synergy between central actions of estrogens and leptin has been demonstrated to protect ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea50ec13163a71892a9a6c287661c81
https://pub.dzne.de/record/256515
https://pub.dzne.de/record/256515
Autor:
Enrica Montalban, Roman Walle, Julien Castel, Anthony Ansoult, Rim Hassouna, Ewout Foppen, Xi Fang, Zach Hutelin, Sophie Mickus, Emily Perszyk, Anna Petitbon, Jérémy Berthelet, Fernando Rodrigues-Lima, Alberto Cebrian-Serrano, Giuseppe Gangarossa, Claire Martin, Pierre Trifilieff, Clémentine Bosch-Bouju, Dana M. Small, Serge Luquet
Publikováno v:
Biological psychiatry. Elsevier USA
Background: A large body of evidence highlights the importance of genetic variants in the development of psychiatric and metabolic conditions. Among these, the TaqIA polymorphism is one of the most commonly studied in psychiatry. TaqIA is located in
Autor:
Polinka Hernandez-Pliego, Daniel Biggs, Samy Alghadban, Peter Donnelly, Chris Preece, Daniela Moralli, Gang Zhang, Simon Myers, Philipp W. Becker, Anjali Gupta Hinch, Alberto Cebrian-Serrano, Benjamin Davies
Publikováno v:
Molecular Biology and Evolution
Sterility or subfertility of male hybrid offspring is commonly observed. This phenomenon contributes to reproductive barriers between the parental populations, an early step in the process of speciation. One frequent cause of such infertility is a fa
Autor:
Enrica Montalban, Roman Walle, Julien Castel, Anthony Ansoult, Rim Hassouna, Ewout Foppen, Xi Fang, Zach Hutelin, Sophie Mickus, Emily Perszyk, Anna Petitbon, Jérémy Berthelet, Fernando Rodrigues-Lima, Alberto Cebrian-Serrano, Giuseppe Gangarossa, Claire Martin, Pierre Trifilieff, Clémentine Bosch-Bouju, Dana. M Small, Serge Luquet
Significant evidence highlights the importance of genetic variants in the development of psychiatric and metabolic conditions. Among these, the Taq1A polymorphism is one of the most commonly studied in psychiatry. TaqIA is located in the gene that co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d262dbdde61b2240c218c807ca2dc3ad
https://doi.org/10.1101/2022.08.12.503577
https://doi.org/10.1101/2022.08.12.503577
Autor:
Alberto Cebrian-Serrano, Benjamin Davies, Enrico Castroflorio, Andrew R. Bassett, Peter L. Oliver, Daria M. Svistunova, Mattéa J. Finelli, Joery den Hoed, Silvia Corrochano
Publikováno v:
Cellular and Molecular Life Sciences
Abstract Members of the Tre2/Bub2/Cdc16 (TBC), lysin motif (LysM), domain catalytic (TLDc) protein family are associated with multiple neurodevelopmental disorders, although their exact roles in disease remain unclear. For example, nuclear receptor c