Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alberto Bravo-Blas"'
Autor:
Jamie I. Scott, Lorena Mendive-Tapia, Doireann Gordon, Nicole D. Barth, Emily J. Thompson, Zhiming Cheng, David Taggart, Takanori Kitamura, Alberto Bravo-Blas, Edward W. Roberts, Jordi Juarez-Jimenez, Julien Michel, Berber Piet, I. Jolanda de Vries, Martijn Verdoes, John Dawson, Neil O. Carragher, Richard A. O’ Connor, Ahsan R. Akram, Margaret Frame, Alan Serrels, Marc Vendrell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Granzyme B is found in activated T cells and can be used as a marker of T cell activation. Here, the authors generate a fluorescent probe that can detect Granzyme B levels in tumours, and has the potential to be used as a biomarker of response to imm
Externí odkaz:
https://doaj.org/article/773a1c7cda434f51a8e1ac084abce313
Autor:
Pamela B. Wright, Elizabeth McDonald, Alberto Bravo-Blas, Hannah M. Baer, Anna Heawood, Calum C. Bain, Allan M. Mowat, Slater L. Clay, Elaine V. Robertson, Fraser Morton, Jagtar Singh Nijjar, Umer Z. Ijaz, Simon W. F. Milling, Daniel R. Gaya
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it is necessary to identify functionally-different MNP population
Externí odkaz:
https://doaj.org/article/4a39c7bad69f4132860514691588ed0f
Autor:
Nuria Carpena, Kerry Richards, Teresita D. J. Bello Gonzalez, Alberto Bravo-Blas, Nicholas G. Housden, Konstantinos Gerasimidis, Simon W. F. Milling, Gillian Douce, Danish J. Malik, Daniel Walker
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models ar
Externí odkaz:
https://doaj.org/article/221a8f21675c4c71bcd4759b011ab381
Mucosal CD8 T Cell Responses Are Shaped by Batf3-DC After Foodborne Listeria monocytogenes Infection
Autor:
Jessica Nancy Imperato, Daqi Xu, Pablo A. Romagnoli, Zhijuan Qiu, Pedro Perez, Camille Khairallah, Quynh-Mai Pham, Anna Andrusaite, Alberto Bravo-Blas, Simon W. F. Milling, Leo Lefrancois, Kamal M. Khanna, Lynn Puddington, Brian S. Sheridan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
While immune responses have been rigorously examined after intravenous Listeria monocytogenes (Lm) infection, less is understood about its dissemination from the intestines or the induction of adaptive immunity after more physiologic models of foodbo
Externí odkaz:
https://doaj.org/article/195b3533c6a34c798d5182f55531452d
Autor:
Calum C. Bain, Pieter A. Louwe, Nicholas J. Steers, Alberto Bravo‐Blas, Lizi M. Hegarty, Clare Pridans, Simon W.F. Milling, Andrew S. MacDonald, Dominik Rückerl, Stephen J. Jenkins
Publikováno v:
Bain, C C, Louwe, P A, Steers, N, Bravo-Blas, A, Hegarty, L, Pridans, C, Milling, S, MacDonald, A S, Ruckerl, D & Jenkins, S J 2022, ' CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice ', European Journal of Immunology, vol. 52, no. 8, pp. 1243-1257 . https://doi.org/10.1002/eji.202149756
Bain, C C, Louwe, P A, Steers, N J, Bravo-Blas, A, Hegarty, L M, Pridans, C, Milling, S W F, MacDonald, A S, Rückerl, D & Jenkins, S J 2022, ' CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice ', European journal of immunology . https://doi.org/10.1002/eji.202149756
Bain, C C, Louwe, P A, Steers, N J, Bravo-Blas, A, Hegarty, L M, Pridans, C, Milling, S W F, MacDonald, A S, Rückerl, D & Jenkins, S J 2022, ' CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice ', European journal of immunology . https://doi.org/10.1002/eji.202149756
The murine serous cavities contain a rare and enigmatic population of short-lived F4/80 loMHCII + macrophages but what regulates their development, survival, and fate is unclear. Here, we show that mature F4/80 loMHCII + peritoneal macrophages arise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ff8dc24f598395d90d3549f866efb6
https://www.pure.ed.ac.uk/ws/files/290984053/Eur_J_Immunol_2022_Bain_CD11c_identifies_microbiota_and_EGR2_u2010dependent_MHCII_serous_cavity_macrophages_with_sexually.pdf
https://www.pure.ed.ac.uk/ws/files/290984053/Eur_J_Immunol_2022_Bain_CD11c_identifies_microbiota_and_EGR2_u2010dependent_MHCII_serous_cavity_macrophages_with_sexually.pdf
Publikováno v:
Mucosal Immunology
FoxP3+ regulatory T cells (Tregs) control inflammation and maintain mucosal homeostasis, but their functions during infection are poorly understood. Th1, Th2 and Th17 cells can be identified by master transcription factors (TFs) T-bet, GATA3 and ROR
Autor:
Calum C, Bain, Pieter A, Louwe, Nicholas J, Steers, Alberto, Bravo-Blas, Lizi M, Hegarty, Clare, Pridans, Simon W F, Milling, Andrew S, MacDonald, Dominik, Rückerl, Stephen J, Jenkins
Publikováno v:
European journal of immunology. 52(8)
The murine serous cavities contain a rare and enigmatic population of short-lived F4/80
Autor:
Simon Milling, Danish J. Malik, Alberto Bravo-Blas, Daniel Walker, Kerry Richards, Konstantinos Gerasimidis, Nicholas G. Housden, Teresita D. J. Bello Gonzalez, Nuria Carpena, Gillian Douce
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, 12
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology 12 (2021)
Frontiers in Microbiology, 12
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology 12 (2021)
Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models ar
Autor:
Daniel R. Gaya, Simon Milling, Hannah M Baer, Elizabeth McDonald, Allan McI. Mowat, Slater L. Clay, Calum C. Bain, Umer Zeeshan Ijaz, Alberto Bravo-Blas, Anna Heawood, Pamela B. Wright, F. Morton, Jagtar Singh Nijjar, Elaine V Robertson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it is necessary to identify functionally-different MNP populations. We aim
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 147:106227
Despite their low abundance in tumours conventional dendritic cells play an outsized role in initiating and perpetuating anti-tumour immunity; however progressively growing tumours suppress dendritic cell function in a range of ways preventing effect