Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alberto Bencomo"'
Autor:
Laura García-Pupo, Lucie Crouzier, Alberto Bencomo-Martínez, Johann Meunier, Axelle Morilleau, Benjamin Delprat, Marquiza Sablón Carrazana, Roberto Menéndez Soto del Valle, Tangui Maurice, Chryslaine Rodríguez-Tanty
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4345-4359 (2024)
The aggregation of Amyloid-β (Aβ) peptides is associated with neurodegeneration in Alzheimer's disease (AD). We previously identified novel naphtalene derivatives, including the lead compound Amylovis-201, able to form thermodynamically stable comp
Externí odkaz:
https://doaj.org/article/26f1239b7fa54d17870873e42f89e4c4
Autor:
Alberto Bencomo-Martínez, Marquiza Sablón-Carrazana, Suchitil Rivera-Marrero, Chryslaine Rodríguez-Tanty, Yoanna María Álvarez-Ginarte, Amaury Pupo-Meriño
Publikováno v:
Revista CENIC Ciencias Químicas, Vol 43, Iss 1, Pp 01-014 (2012)
La enfermedad de Alzheimer (EA) es un desorden neurodegenerativo caracterizado por la acumulación de placas amiloides en el cerebro. Es la principal causa de demencia en los ancianos y no existe ningún tratamiento disponible contra ella. Evidencias
Externí odkaz:
https://doaj.org/article/ca09079c92644973a7cd8fdeedc1f03f
Autor:
Isaac Fernández-Gómez, Marquiza Sablón-Carrazana, Alberto Bencomo-Martínez, Guadalupe Domínguez, Reyna Lara-Martínez, Nelly F. Altamirano-Bustamante, Luis Felipe Jiménez-García, Karina Pasten-Hidalgo, Rosa Angélica Castillo-Rodríguez, Perla Altamirano, Suchitil Rivera Marrero, Cristina Revilla-Monsalve, Peter Valdés-Sosa, Fabio Salamanca-Gómez, Eulalia Garrido-Magaña, Chryslaine Rodríguez-Tanty, Myriam M. Altamirano-Bustamante
Publikováno v:
Molecules, Vol 23, Iss 3, p 686 (2018)
Human islet amyloid peptide (hIAPP1–37) aggregation is an early step in Diabetes Mellitus. We aimed to evaluate a family of pharmaco-chaperones to act as modulators that provide dynamic interventions and the multi-target capacity (native state, cyt
Externí odkaz:
https://doaj.org/article/b8c1b1834cc6469c89a87b331ebe453f
Autor:
Marquiza Sablón-Carrazana, Isaac Fernández, Alberto Bencomo, Reyna Lara-Martínez, Suchitil Rivera-Marrero, Guadalupe Domínguez, Rafaela Pérez-Perera, Luis Felipe Jiménez-García, Nelly F Altamirano-Bustamante, Massiel Diaz-Delgado, Fernand Vedrenne, Lina Rivillas-Acevedo, Karina Pasten-Hidalgo, María de Lourdes Segura-Valdez, Sergio Islas-Andrade, Eulalia Garrido-Magaña, Alejandro Perera-Pintado, Anaís Prats-Capote, Chryslaine Rodríguez-Tanty, Myriam M Altamirano-Bustamante
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0135292 (2015)
The increasing prevalence of conformational diseases, including Alzheimer's disease, type 2 Diabetes Mellitus and Cancer, poses a global challenge at many different levels. It has devastating effects on the sufferers as well as a tremendous economic
Externí odkaz:
https://doaj.org/article/1344ee3767f543d39982f94d11ff7837
Autor:
Geyla Dubed-Bandomo, Florencia Zoppolo, Samila León-Chaviano, Suchitil Rivera-Marrero, Alberto Bencomo-Martínez, Ingrid Kreimerman, Chryslaine Rodríguez-Tanty, Alejandro Perera-Pintado, Luis A. Espinosa-Rodríguez, Laura Fernandez-Maza, Laura Reyes, Marcin Balcerzyk, Daymara Mercerón-Martínez, Henry Engler, Marquiza Sablón-Carrazana, Eduardo Savio, Anaís Prats-Capote, Tania Pardo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Background] Alzheimer’s disease (AD) is the most common form of dementia. Neuroimaging methods have widened the horizons for AD diagnosis and therapy. The goals of this work are the synthesis of 2-(3-fluoropropyl)-6-methoxynaphthalene (5) and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46296508080d3ecbd55db705fe4eb0b7
https://doi.org/10.2174/1874471012666190102165053
https://doi.org/10.2174/1874471012666190102165053
Autor:
Yoana Pérez Badel, Eda Suku, Alberto Bencomo-Martínez, Valentina Guaitoli, Luis Alberto Montero-Cabrera, Yoanna María Alvarez-Ginarte, Alejandro Giorgetti
Publikováno v:
Journal of Molecular Modeling. 26
We followed a comprehensive computational strategy to understand and eventually predict the structure-activity relationship of thirty-three 1,3-disubstituted imidazole [1,5-α] pyrazine derivatives described as ATP competitive inhibitors of the IGF-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030ec4f76b98e1d94c3b94298912b5d5
https://doi.org/10.1007/s00894-020-04470-w
https://doi.org/10.1007/s00894-020-04470-w
Autor:
Cristina Revilla-Monsalve, Eulalia P. Garrido-Magaña, Perla Altamirano, Karina Pasten-Hidalgo, Myriam M. Altamirano-Bustamante, Fabio Salamanca-Gómez, Isaac Fernandez-Gomez, Peter Valdés-Sosa, Luis Felipe Jiménez-García, Guadalupe Domínguez, Suchitil Rivera Marrero, Alberto Bencomo-Martínez, Nelly F. Altamirano-Bustamante, Chryslaine Rodríguez-Tanty, Marquiza Sablón-Carrazana, Rosa Angélica Castillo-Rodríguez, Reyna Lara-Martínez
Publikováno v:
Molecules, Vol 23, Iss 3, p 686 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 23; Issue 3; Pages: 686
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 23; Issue 3; Pages: 686
Human islet amyloid peptide (hIAPP1–37) aggregation is an early step in Diabetes Mellitus. We aimed to evaluate a family of pharmaco-chaperones to act as modulators that provide dynamic interventions and the multi-target capacity (native state, cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411e4c850e7cded369f2f064abc4568d
http://www.mdpi.com/1420-3049/23/3/686
http://www.mdpi.com/1420-3049/23/3/686
Autor:
Lina Rivillas-Acevedo, Chryslaine Rodríguez-Tanty, Fernand Vedrenne, Alberto Bencomo, Suchitil Rivera-Marrero, Alejandro Perera-Pintado, Guadalupe Domínguez, Myriam M. Altamirano-Bustamante, Karina Pasten-Hidalgo, Nelly F. Altamirano-Bustamante, María de Lourdes Segura-Valdez, Luis Felipe Jiménez-García, Rafaela Pérez-Perera, Sergio Islas-Andrade, Marquiza Sablón-Carrazana, Anaís Prats-Capote, Eulalia P. Garrido-Magaña, Massiel Diaz-Delgado, Gomez Isaac Fernandez, Reyna Lara-Martínez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0135292 (2015)
PLoS ONE, Vol 10, Iss 9, p e0135292 (2015)
The increasing prevalence of conformational diseases, including Alzheimer's disease, type 2 Diabetes Mellitus and Cancer, poses a global challenge at many different levels. It has devastating effects on the sufferers as well as a tremendous economic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3479f0586c0c9ce7e66a89c0e6fbc046
https://pubmed.ncbi.nlm.nih.gov/26327208
https://pubmed.ncbi.nlm.nih.gov/26327208
Autor:
Myriam M. Altamirano-Bustamante, Julio Morán, Marquiza Sablón-Carrazana, Luis Felipe Jimenez, Karina Pasten-Hidalgo, Rosa Angélica Castillo-Rodríguez, Eulalia P. Garrido-Magaña, Alberto Bencomo, Isaac Fernandez-Gomez, Sergio Islas-Andrade, Chryslaine Rodríguez-Tanty, Nelly F. Altamirano-Bustamante, Guadalupe Domínguez, Reyna Lara
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c759b1a8417919a350e6d5a0cf39881c
https://doi.org/10.1530/endoabs.37.ep437
https://doi.org/10.1530/endoabs.37.ep437
Autor:
Alina Agramonte-Delgado, José M. García de la Vega, Alberto Bencomo-Martínez, Yovani Marrero-Ponce, José Alberto Ruiz-García, Yoanna María Alvarez-Ginarte, Hans Mikosch, Amaury Pupo, Luis A. Montero-Cabrera
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 138
Parallel ligand- and structure-based virtual screenings of 269 steroids with anabolic activity evaluated in vivo were performed. The quantitative structure-activity relationship (QSAR) model expressed by selected descriptors as the octanol-water part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f71d6b62c3bb8906d4ded9c13e99221
https://pubmed.ncbi.nlm.nih.gov/23872659
https://pubmed.ncbi.nlm.nih.gov/23872659