Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Alberto Bavelloni"'
Autor:
Sara Salucci, Alberto Bavelloni, Ilaria Versari, Sabrina Burattini, Francesco Bavelloni, Pietro Gobbi, Alessandro Fanzani, Silvia Codenotti, William Blalock, Katia Scotlandi, Irene Faenza
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1180 (2024)
Rhabdomyosarcoma (RMS), the most common form of sarcoma typical of pediatric age, arises from the malignant transformation of the mesenchymal precursors that fail to differentiate into skeletal muscle cells. Here, we investigated whether the protein
Externí odkaz:
https://doaj.org/article/3f27de51a5ce437fa12ac8451df1caf7
Autor:
Sara Salucci, Sabrina Burattini, Ilaria Versari, Alberto Bavelloni, Francesco Bavelloni, Davide Curzi, Michela Battistelli, Pietro Gobbi, Irene Faenza
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 9, Iss 3, p 124 (2024)
Prolonged exposure to high dosages of dexamethasone, which is a synthetic glucocorticoid and a well-known anti-inflammatory drug, may lead to an increase in reactive oxygen species production, contributing to muscle wasting. The prevention of muscle
Externí odkaz:
https://doaj.org/article/c6ceea837a7d42f4b7b85b71cff58228
Publikováno v:
Genes, Vol 14, Iss 7, p 1386 (2023)
The advent of next generation sequencing (NGS) has fostered a shift in basic analytic strategies of a gene expression analysis in diverse pathologies for the purposes of research, pharmacology, and personalized medicine. What was once highly focused
Externí odkaz:
https://doaj.org/article/b2b303fda4ac47d891e115419961f839
Autor:
Camilla Cristalli, Maria Cristina Manara, Sergio Valente, Evelin Pellegrini, Alberto Bavelloni, Alessandra De Feo, William Blalock, Elisabetta Di Bello, David Piñeyro, Angelika Merkel, Manel Esteller, Oscar M. Tirado, Antonello Mai, Katia Scotlandi
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
DNA methylation is an important component of the epigenetic machinery that regulates the malignancy of Ewing sarcoma (EWS), the second most common primary bone tumor in children and adolescents. Coordination of DNA methylation and DNA replication is
Externí odkaz:
https://doaj.org/article/72d7fec2ed6148faa9ae41cddd9e0221
Autor:
Sara Salucci, Alberto Bavelloni, Anna Bartoletti Stella, Francesco Fabbri, Ivan Vannini, Manuela Piazzi, Karyna Volkava, Katia Scotlandi, Giovanni Martinelli, Irene Faenza, William Blalock
Publikováno v:
Nutrients, Vol 15, Iss 3, p 740 (2023)
Approximately 7% of cancers arising in children and 1% of those arising in adults are soft tissue sarcomas (STS). Of these malignancies, rhabdomyosarcoma (RMS) is the most common. RMS survival rates using current therapeutic protocols have remained l
Externí odkaz:
https://doaj.org/article/e99582ac5bd0418ab61d25475859f42a
Autor:
Sara Salucci, Anna Bartoletti-Stella, Alberto Bavelloni, Beatrice Aramini, William L. Blalock, Francesco Fabbri, Ivan Vannini, Vittorio Sambri, Franco Stella, Irene Faenza
Publikováno v:
Nutrients, Vol 14, Iss 17, p 3567 (2022)
Aging results in a progressive decline in skeletal muscle mass, strength and function, a condition known as sarcopenia. This pathological condition is due to multifactorial processes including physical inactivity, inflammation, oxidative stress, horm
Externí odkaz:
https://doaj.org/article/0a973c5aab03498ea653314783920e2e
Autor:
Manuela Piazzi, Alberto Bavelloni, Vittoria Cenni, Sara Salucci, Anna Bartoletti Stella, Enrica Tomassini, Katia Scotlandi, William L. Blalock, Irene Faenza
Publikováno v:
Molecules, Vol 27, Iss 9, p 2742 (2022)
Rhabdomyosarcoma (RMS) is a highly malignant and metastatic pediatric cancer arising from skeletal muscle myogenic progenitors. Recent studies have shown an important role for AKT signaling in RMS progression. Aberrant activation of the PI3K/AKT axis
Externí odkaz:
https://doaj.org/article/04584bf6374340ca95d2de37b203df1a
Autor:
Silvia Grassilli, Federica Brugnoli, Rossano Lattanzio, Marco Marchisio, Letizia Perracchio, Mauro Piantelli, Alberto Bavelloni, Silvano Capitani, Valeria Bertagnolo
Publikováno v:
Molecular Oncology, Vol 12, Iss 7, Pp 1012-1025 (2018)
Targeting different members of the Akt pathways is a promising therapeutic chance in solid tumors including breast cancer. The variable expression levels of Akt isoforms with opposite effects on tumor growth and metastasis, however, make it difficult
Externí odkaz:
https://doaj.org/article/9caafccd50054d279fb438d0ec5dd318
Publikováno v:
Cells, Vol 10, Iss 11, p 3255 (2021)
Idiopathic or sporadic inclusion body myositis (IBM) is the leading age-related (onset >50 years of age) autoimmune muscular pathology, resulting in significant debilitation in affected individuals. Once viewed as primarily a degenerative disorder, i
Externí odkaz:
https://doaj.org/article/50b65513378841e1aa7a4d66684e76ad
Autor:
Sara Salucci, Anna Bartoletti Stella, Michela Battistelli, Sabrina Burattini, Alberto Bavelloni, Lucio Ildebrando Cocco, Pietro Gobbi, Irene Faenza
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1109 (2021)
Neuro-muscular disorders include a variety of diseases induced by genetic mutations resulting in muscle weakness and waste, swallowing and breathing difficulties. However, muscle alterations and nerve depletions involve specific molecular and cellula
Externí odkaz:
https://doaj.org/article/6b246989df1d4e6ca3f0b36995416de1