Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alberto B, Silva"'
Autor:
Tariq Afroz, Elodie Chevalier, Mickael Audrain, Christopher Dumayne, Tamar Ziehm, Roger Moser, Anne-Laure Egesipe, Lorène Mottier, Monisha Ratnam, Manuela Neumann, Daniel Havas, Romain Ollier, Kasia Piorkowska, Mayank Chauhan, Alberto B. Silva, Samjhana Thapa, Jan Stöhr, Andrej Bavdek, Valerie Eligert, Oskar Adolfsson, Peter T. Nelson, Sílvia Porta, Virginia M.-Y. Lee, Andrea Pfeifer, Marie Kosco-Vilbois, Tamara Seredenina
Publikováno v:
Neurobiology of Disease, Vol 179, Iss , Pp 106050- (2023)
Effective therapies are urgently needed to safely target TDP-43 pathology as it is closely associated with the onset and development of devastating diseases such as frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) and amyotrophic la
Externí odkaz:
https://doaj.org/article/0ae8a176004d45538a54e3b880d79375
Autor:
Mark A. T. Blaskovich, Karl A. Hansford, Yujing Gong, Mark S. Butler, Craig Muldoon, Johnny X. Huang, Soumya Ramu, Alberto B. Silva, Mu Cheng, Angela M. Kavanagh, Zyta Ziora, Rajaratnam Premraj, Fredrik Lindahl, Tanya A. Bradford, June C. Lee, Tomislav Karoli, Ruby Pelingon, David J. Edwards, Maite Amado, Alysha G. Elliott, Wanida Phetsang, Noor Huda Daud, Johan E. Deecke, Hanna E. Sidjabat, Sefetogi Ramaologa, Johannes Zuegg, Jason R. Betley, Andrew P. G. Beevers, Richard A. G. Smith, Jason A. Roberts, David L. Paterson, Matthew A. Cooper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The antibiotic vancomycin inhibits bacterial cell wall synthesis by binding to a membrane-associated precursor. Here, Blaskovich et al. synthesize vancomycin derivatives containing lipophilic peptide moieties that enhance membrane affinity and in viv
Externí odkaz:
https://doaj.org/article/5939bc54d4b347d7b1b16946d6d5c490
Autor:
Alessandre Sampaio-Silva, Gervásio Protásio dos Santos Cavalcante, Carlos Alberto B. Silva, Jordan Del Nero
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 18:1714-1723
This work presents an investigation on the electronic transport of two devices based on Zigzag Phagraphene Nanoribbons of different widths (ZPGNR1 and ZPGNR2) with Nitrogen-doped edge terminations based on DFT-NEGF methodology using TranSIESTA code.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b346693f2273e1b3bf1199e3a33a7887
https://doi.org/10.1166/jctn.2021.9729
https://doi.org/10.1166/jctn.2021.9729
Autor:
Avril A. B. Robertson, James A. Fraser, Ulrike Kappler, Amanda Nouwens, Mark E. Cooper, Lalith Kumar Kummari, Ross D. Blundell, Alberto B. Silva, Mark S. Butler, Bostjan Kobe, Emily Furlong
Publikováno v:
Bioorganicmedicinal chemistry. 26(20)
Fungi cause serious life-threatening infections in immunocompromised individuals and current treatments are now complicated by toxicity issues and the emergence of drug resistant strains. Consequently, there is a need for development of new antifunga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4abaa46b1ab8599d1843efb908ff30
https://pubmed.ncbi.nlm.nih.gov/30322754
https://pubmed.ncbi.nlm.nih.gov/30322754
Autor:
Hanna E. Sidjabat, David Edwards, Andrew P. G. Beevers, Ruby Pelingon, Zyta M. Ziora, Karl A. Hansford, Fredrik Lindahl, Noor Huda Daud, Sefetogi Ramaologa, Tanya A. Bradford, Jason A. Roberts, Mark E. Cooper, Angela M. Kavanagh, June C. Lee, Yujing Gong, David L. Paterson, Soumya Ramu, Maite Amado, Wanida Phetsang, Tomislav Karoli, Johannes Zuegg, Alberto B. Silva, Johnny X. Huang, Alysha G. Elliott, Mark S. Butler, Richard A. G. Smith, Rajaratnam Premraj, Craig Muldoon, Mark A. T. Blaskovich, Mu Cheng, Johan E. Deecke, Jason Betley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
The public health threat posed by a looming ‘post-antibiotic’ era necessitates new approaches to antibiotic discovery. Drug development has typically avoided exploitation of membrane-binding properties, in contrast to nature’s control of biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7366661a67b35b8ed35840cfd588645
https://doi.org/10.1038/s41467-017-02123-w
https://doi.org/10.1038/s41467-017-02123-w
Autor:
Adrian B. Hehl, Kamile Grabliauskaite, Theresia Reding, Rolf Graf, Enrica Saponara, Yinghua Tian, Alberto B. Silva, Elisabeth M. Schraner, Sabrina Sonda, Ermanno Malagola, Gitta Maria Seleznik, Raphael M Buzzi, Marta Bombardo, Anja Zabel
Publikováno v:
The Journal of Pathology. 237:495-507
The exocrine pancreas exhibits a distinctive capacity for tissue regeneration and renewal following injury. This regenerative ability has important implications for a variety of disorders, including pancreatitis and pancreatic cancer, diseases associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952e26b9f9b0372e0228248534723678
https://doi.org/10.1002/path.4595
https://doi.org/10.1002/path.4595
Autor:
S Y Kim, Theresia Reding, U Wagner, Rolf Graf, Li-Kang Sun, Martha Bain, Daniel Bimmler, Alberto B. Silva
Publikováno v:
Physiological Genomics. 38:196-204
The pathophysiology of human chronic pancreatitis is not well understood and difficult to follow on a molecular basis. Therefore, we used a rat model [Wistar-Bonn/Kobori (WBN/Kob)] that exhibits spontaneous chronic inflammation and fibrosis in the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90ce640c1031d10d15c8712aa333a2f
https://doi.org/10.1152/physiolgenomics.00028.2009
https://doi.org/10.1152/physiolgenomics.00028.2009
Publikováno v:
Aging
T cells are an integral part of a functional immune system with the majority being produced in the thymus. Of all the changes related to immunosenescence, regression of the thymus is considered one of the most universally recognised alterations. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e371523edc637cb141d2cc9ae9c19b03
https://doi.org/10.18632/aging.100027
https://doi.org/10.18632/aging.100027
Autor:
Enrica, Saponara, Kamile, Grabliauskaite, Marta, Bombardo, Raphael, Buzzi, Alberto B, Silva, Ermanno, Malagola, Yinghua, Tian, Adrian B, Hehl, Elisabeth M, Schraner, Gitta M, Seleznik, Anja, Zabel, Theresia, Reding, Sabrina, Sonda, Rolf, Graf
Publikováno v:
The Journal of pathology. 237(4)
The exocrine pancreas exhibits a distinctive capacity for tissue regeneration and renewal following injury. This regenerative ability has important implications for a variety of disorders, including pancreatitis and pancreatic cancer, diseases associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cc14028e93214a2b21a79ca113dd457
https://pubmed.ncbi.nlm.nih.gov/26235267
https://pubmed.ncbi.nlm.nih.gov/26235267
Publikováno v:
Immunology. 118:131-140
Evidence suggests that the immune and neuroendocrine systems cross talk by sharing ligands and receptors. Hormones and neuropeptides produced by the neuroendocrine system often modulate the function of lymphoid organs and immune cells. We have previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3647615eb71696fa1818e256b8c5b689
https://doi.org/10.1111/j.1365-2567.2006.02351.x
https://doi.org/10.1111/j.1365-2567.2006.02351.x