Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome

Autor: Calogera Pisano, Alessandra Iaccarino, Michele Madonna, Carmela Rita Balistreri, Mariangela Peruzzi, Valeriana Cesarini, Giacomo Frati, Elena Cavarretta, Alberto Allegra, Michele Torella, Sebastiano Sciarretta, Antonino G.M. Marullo, Giovanni Ruvolo, Sonia Schiavon, Ernesto Greco

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific reports (Nature Publishing Group) 9 (2019). doi:10.1038/s41598-019-47412-0
info:cnr-pdr/source/autori:Balistreri, Carmela R.; Marullo, Antonino G. M.; Madonna, Michele; Cavarretta, Elena; Allegra, Alberto; Cesarini, Valeriana; Iaccarino, Alessandra; Schiavon, Sonia; Peruzzi, Mariangela; Greco, Ernesto; Sciarretta, Sebastiano; Pisano, Calogera; Ruvolo, Giovanni; Torella, Michele; Frati, Giacomo/titolo:Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome/doi:10.1038%2Fs41598-019-47412-0/rivista:Scientific reports (Nature Publishing Group)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Scientific Reports

Bicuspid aortic valve (BAV) disease is recognized to be a syndrome with a complex and multifaceted pathophysiology. Its progression is modulated by diverse evolutionary conserved pathways, such as Notch-1 pathway. Emerging evidence is also highlighti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a77ea04200c2a0c9ceb13eebf97223b
https://doi.org/10.1038/s41598-019-47412-0

A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

Autor: Calogera Pisano, Carmela Rita Balistreri, Giovanni Ruvolo, Giacomo Frati, Antonino G.M. Marullo, Domenico Lio, Giuseppina Colonna-Romano, Sebastiano Sciarretta, Sonia Schiavon, Alberto Allegra, Giuseppe Mazzesi, Ernesto Greco, Elena Cavarretta, Silvio Buffa, Silvia Palmerio

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Oxidative Medicine and Cellular Longevity

Bicuspid valve disease is associated with the development of thoracic aortic aneurysm. The molecular mechanisms underlying this association still need to be clarified. Here, we evaluated the circulating levels of T and B lymphocyte subsets associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec669e44339037586f4b819797e7ca0
http://hdl.handle.net/2108/197165

Associations of rs3918242 and rs2285053 MMP-9 and MMP-2 polymorphisms with the risk, severity, and short- and long-term complications of degenerative mitral valve diseases: A 4.8-year prospective cohort study

Autor: Calogera Pisano, Alberto Allegra, Carmela Rita Balistreri, Giuseppina Candore, Giovanni Ruvolo, Domenico Lio, Oreste Fabio Triolo, Vincenzo Argano, Floriana Crapanzano

Background Degenerative forms of mitral valve diseases (MVDs) are very complex pathologies. Thus, it is difficult to make generalizations about the disease pathways or genetic risk factors contributing to these diseases. However, a key role of metall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3e1481332b6939de504b1a076fa488
http://hdl.handle.net/10447/180094