Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alberto, Sada Japp"'
Autor:
Christos Nikolaou, Kerstin Muehle, Stephan Schlickeiser, Alberto Sada Japp, Nadine Matzmohr, Desiree Kunkel, Marco Frentsch, Andreas Thiel
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Immune ageing is a result of repetitive microbial challenges along with cell intrinsic or systemic changes occurring during ageing. Mice under ‘specific-pathogen-free’ (SPF) conditions are frequently used to assess immune agei
Externí odkaz:
https://doaj.org/article/8d32dcc8dc104467bb34b78befd1178c
Autor:
Sarah A. Overall, Jugmohit S. Toor, Stephanie Hao, Mark Yarmarkovich, Sara M. O’Rourke, Giora I. Morozov, Son Nguyen, Alberto Sada Japp, Nicolas Gonzalez, Danai Moschidi, Michael R. Betts, John M. Maris, Peter Smibert, Nikolaos G. Sgourakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Peptide-MHC (pMHC) tetramers are important tools for probing T cell repertoire and adaptive immune responses. Here the authors use a molecular chaperone, TAPBPR, to develop a high-throughput, multiplexible platform for pMHC tetramer generation to fac
Externí odkaz:
https://doaj.org/article/975b9e150895476f87a40ab18d6ce573
Autor:
Morgan A. Reuter, Perla M. Del Rio Estrada, Marcus Buggert, Constantinos Petrovas, Sara Ferrando-Martinez, Son Nguyen, Alberto Sada Japp, Yuria Ablanedo-Terrazas, Amaranta Rivero-Arrieta, Leticia Kuri-Cervantes, Heidi M. Gunzelman, Emma Gostick, David A. Price, Richard A. Koup, Ali Naji, David H. Canaday, Gustavo Reyes-Terán, Michael R. Betts
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3458-3470 (2017)
Summary: Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8+ T cells play a critical role in control of HIV, but their functional attributes in lymph nodes (LNs) remain unclear. Here, we show that memory,
Externí odkaz:
https://doaj.org/article/6bc44c6e41074190a760d0bb474a3be4
Autor:
Christos Nikolaou, Kerstin Muehle, Stephan Schlickeiser, Alberto Sada Japp, Nadine Matzmohr, Desiree Kunkel, Marco Frentsch, Andreas Thiel
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e41d050784bf48ae96cfdbe1dc51cf05
Autor:
Andreas Habertheuer, Shampa Chatterjee, Alberto Sada Japp, Chirag Ram, Laxminarayana Korutla, Takahiro Ochiya, Wenjun Li, Yuriko Terada, Tsuyoshi Takahashi, Ruben G. Nava, Varun Puri, Daniel Kreisel, Prashanth Vallabhajosyula
Publikováno v:
American Journal of Transplantation. 22:1909-1918
Restoration of lymphatic drainage across the bronchial anastomosis after lung transplantation requires several weeks. As donor antigen and antigen presenting cell trafficking via lymphatics into graft-draining lymph nodes is an important component of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a202a3903f66d1232b807588c4e4a3a
https://doi.org/10.1111/ajt.17023
https://doi.org/10.1111/ajt.17023
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2521
The efficient expression of T-cell receptors (TCRs) or chimeric antigen receptors (CARs) in primary human T cells is crucial for preclinical testing of receptor properties for adoptive T-cell therapies. Multiple streams of technological platforms hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c311adeb01d5e8104a888c2ef532d702
https://pubmed.ncbi.nlm.nih.gov/35732994
https://pubmed.ncbi.nlm.nih.gov/35732994
Publikováno v:
Molecular Immunology
Highlights • While blood CD8+ T cells control HIV using cytolytic functions, lymphoid tissue CD8+ T cells do so via non-cytolytic functions • HIV-specific CD8+ T cells in lymphoid and mucosal tissues are largely tissue-resident memory cells • T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025da933d72d4bc373044aef32940318
https://doi.org/10.1016/j.molimm.2020.05.016
https://doi.org/10.1016/j.molimm.2020.05.016
Autor:
Peter Smibert, Stephanie Hao, Nikolaos G. Sgourakis, Sara M. O'Rourke, Michael R. Betts, Giora I. Morozov, Son Nguyen, Sarah A. Overall, Mark Yarmarkovich, Alberto Sada Japp, Danai Moschidi, John M. Maris, Jugmohit S. Toor, Nicolas Gonzalez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Peptide exchange technologies are essential for the generation of pMHC-multimer libraries used to probe diverse, polyclonal TCR repertoires in various settings. Here, using the molecular chaperone TAPBPR, we develop a robust method for the capture of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecc36051bb06376d532cba9ccd7fa70
https://doaj.org/article/975b9e150895476f87a40ab18d6ce573
https://doaj.org/article/975b9e150895476f87a40ab18d6ce573
Publikováno v:
Methods in Molecular Biology ISBN: 9781071624401
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6725c6630bc24b71b2b0ea793b27bce
https://doi.org/10.1007/978-1-0716-2441-8_5
https://doi.org/10.1007/978-1-0716-2441-8_5
Autor:
Amrit Singh, Anthony P. Schwarer, Helen L. Partridge, Frits van Rhee, Daniel J. Arenas, David C. Fajgenbaum, Katie L. Stone, Mariko Okumura, Jason R. Ruth, Nelson Hamerschlak, Michael R. Betts, Thomas S. Uldrick, Gerald Wertheim, Christopher S. Nabel, Taku Kambayashi, Michael B. Jordan, Sheila K Pierson, Fabio Freire José, Alberto Sada Japp, Arthur H. Rubenstein, Adam D. Cohen, Ruth-Anne Langan, Vera P. Krymskaya
Publikováno v:
Journal of Clinical Investigation. 129:4451-4463
BACKGROUND Idiopathic multicentric Castleman disease (iMCD) is a hematologic illness involving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening multi-organ dysfunction. The molecular underpinnings of inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8033ac4d600fd62a1b2cfd366a713000
https://doi.org/10.1172/jci126091
https://doi.org/10.1172/jci126091