Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Alberto, Mercatanti"'
Autor:
Maristella Canovai, Monica Evangelista, Alberto Mercatanti, Romina D’Aurizio, Letizia Pitto, Francesca Marrocolo, Valentina Casieri, Marco Pellegrini, Vincenzo Lionetti, Sergio Bracarda, Milena Rizzo
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Docetaxel (DCT) resistance is one of the main factors responsible for treatment failure in metastatic prostate cancer (PCa). Although several mechanisms of DCT resistance have been elucidated, the issue is still far from comprehensive. In th
Externí odkaz:
https://doaj.org/article/e8ec5241ae5d4922884fe0067fd7303a
Autor:
Rosetta Ragusa, Arianna Di Molfetta, Alberto Mercatanti, Letizia Pitto, Antonio Amodeo, Maria Giovanna Trivella, Milena Rizzo, Chiara Caselli
Publikováno v:
JHLT Open, Vol 3, Iss , Pp 100041- (2024)
Background: Ventricular assist device (VAD) implant represents a therapeutic option for pediatric patients with end-stage heart failure (HF). Heart unloading by VAD can modify several molecular pathways underlying cardiac function in HF. Among them,
Externí odkaz:
https://doaj.org/article/5cbf52f15a284898b8bfe06ec2306e03
Autor:
Francesca Bellè, Alberto Mercatanti, Samuele Lodovichi, Caterina Congregati, Chiara Guglielmi, Mariella Tancredi, Maria Adelaide Caligo, Tiziana Cervelli, Alvaro Galli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 4049 (2022)
Germline mutations in the BRCA1 gene have been reported to increase the lifetime risk of developing breast and/or ovarian cancer (BOC). By new sequencing technologies, numerous variants of uncertain significance (VUS) are identified. It is mandatory
Externí odkaz:
https://doaj.org/article/222c5ac0e3354152a5f24f72943f1ba2
Autor:
Rosetta Ragusa, Arianna Di Molfetta, Serena Del Turco, Manuela Cabiati, Silvia Del Ry, Giuseppina Basta, Alberto Mercatanti, Letizia Pitto, Antonio Amodeo, Maria Giovanna Trivella, Milena Rizzo, Chiara Caselli
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1409 (2021)
Ventricular Assist Device (VAD) therapy is considered as a part of standard care for end-stage Heart Failure (HF) children unresponsive to medical management, but the potential role of miRNAs in response to VAD therapy on molecular pathways underlyin
Externí odkaz:
https://doaj.org/article/b519e31ccdbd4fa99a77db70aa1c2fb2
Autor:
Andrea Marranci, Zhijie Jiang, Marianna Vitiello, Elena Guzzolino, Laura Comelli, Samanta Sarti, Simone Lubrano, Cinzia Franchin, Ileabett Echevarría-Vargas, Andrea Tuccoli, Alberto Mercatanti, Monica Evangelista, Paolo Sportoletti, Giorgio Cozza, Ettore Luzi, Enrico Capobianco, Jessie Villanueva, Giorgio Arrigoni, Giovanni Signore, Silvia Rocchiccioli, Letizia Pitto, Nicholas Tsinoremas, Laura Poliseno
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-25 (2017)
Abstract Background The BRAF protein kinase is widely studied as a cancer driver and therapeutic target. However, the regulation of its expression is not completely understood. Results Taking advantage of the RNA-seq data of more than 4800 patients b
Externí odkaz:
https://doaj.org/article/2189e3f55b9e4d7fa3863f7e6390bb27
Autor:
Marianna Vitiello, Alberto Mercatanti, Maurizio Salvatore Podda, Caterina Baldanzi, Antonella Prantera, Samanta Sarti, Milena Rizzo, Alessandra Salvetti, Federica Conte, Giulia Fiscon, Paola Paci, Laura Poliseno
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 894
Volume 15
Issue 3
Pages: 894
Background: The ability to increase their degree of pigmentation is an adaptive response that confers pigmentable melanoma cells higher resistance to BRAF inhibitors (BRAFi) compared to non-pigmentable melanoma cells. Methods: Here, we compared the m
Autor:
Francesca Forini, Giuseppina Nicolini, Claudia Kusmic, Romina D’Aurizio, Alberto Mercatanti, Giorgio Iervasi, Letizia Pitto
Publikováno v:
Cells, Vol 9, Iss 10, p 2155 (2020)
The LncRNA my-heart (Mhrt) and the chromatin remodeler Brg1 inhibit each other to respectively prevent or favor the maladaptive α-myosin-heavy-chain (Myh6) to β-myosin-heavy-chain (Myh7) switch, so their balance crucially guides the outcome of card
Externí odkaz:
https://doaj.org/article/bb6b0b6d962b490eb0ed036562c4bf79
Autor:
Sofia Fazio, Gabriele Berti, Francesco Russo, Monica Evangelista, Romina D’Aurizio, Alberto Mercatanti, Marco Pellegrini, Milena Rizzo
Publikováno v:
Cells, Vol 9, Iss 2, p 354 (2020)
miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate cancer (PCa) cells affecting cell proliferation/survival, as well
Externí odkaz:
https://doaj.org/article/0b85f59c8cd14a4ab905db052a9acc62
Autor:
Samuele Lodovichi, Francesca Bellè, Alberto Mercatanti, Laura Spugnesi, Cristina Cozzani, Maria Adelaide Caligo, Tiziana Cervelli, Alvaro Galli
Publikováno v:
FEMS yeast research. 22(1)
The breast and ovarian cancer susceptibility genes, BRCA1 and BRCA2, are key players in the homologous recombination (HR) repair pathway and act as tumor suppressors by maintaining genome stability. The yeast Saccharomyces cerevisiae has no BRCA1/2 h
Autor:
Silvia Del Ry, Manuela Cabiati, Chiara Caselli, Rosetta Ragusa, Maria Giovanna Trivella, Serena Del Turco, Antonio Amodeo, Milena Rizzo, Alberto Mercatanti, Giuseppina Basta, Letizia Pitto, Arianna Di Molfetta
Publikováno v:
Biomedicines
Volume 9
Issue 10
Biomedicines, Vol 9, Iss 1409, p 1409 (2021)
Volume 9
Issue 10
Biomedicines, Vol 9, Iss 1409, p 1409 (2021)
Ventricular Assist Device (VAD) therapy is considered as a part of standard care for end-stage Heart Failure (HF) children unresponsive to medical management, but the potential role of miRNAs in response to VAD therapy on molecular pathways underlyin