Výsledky vyhledávání - "Alberto, Gambalunga"

CuIIand AuIIIComplexes with Glycoconjugated Dithiocarbamato Ligands for Potential Applications in Targeted Chemotherapy

Autor: Alberto Gambalunga, Federica Chiara, Barbara Biondi, Dolores Fregona, Chiara Nardon, Leonardo Brustolin, Andrea Trevisan, Nicolò Pettenuzzo, Elisa Coltri

Publikováno v: ChemMedChem
14 (2019): 1162–1172. doi:10.1002/cmdc.201900226
info:cnr-pdr/source/autori:Pettenuzzo, Nicolo; Brustolin, Leonardo; Coltri, Elisa; Gambalunga, Alberto; Chiara, Federica; Trevisan, Andrea; Biondi, Barbara; Nardon, Chiara; Fregona, Dolores/titolo:Cu-II and Au-III Complexes with Glycoconjugated Dithiocarbamato Ligands for Potential Applications in Targeted Chemotherapy/doi:10.1002%2Fcmdc.201900226/rivista:ChemMedChem (Print)/anno:2019/pagina_da:1162/pagina_a:1172/intervallo_pagine:1162–1172/volume:14

This work is focused on the synthesis, characterization, and preliminary biological evaluation of bio-conjugated Au-III and Cu-II complexes with the aim of overcoming the well-known side effects of chemotherapy by improving the selective accumulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578f3bccb791ec0d0cf39e8b20c9a839
https://doi.org/10.1002/cmdc.201900226

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Neurofibromin Deficiency and Extracellular Matrix Cooperate to Increase Transforming Potential through FAK-Dependent Signaling

Autor: Sandra Giustini, Vincent M Riccardi, Alberto Gambalunga, Anna Stocco, Andrea Rasola, Franco Bassetto, Amedeo Ferlosio, Martina Grigatti, Gianluca Tadini, Andrea Errico, Debora Garozzo, Andrea Trevisan, Federica Chiara, Stefano Ferraresi

Publikováno v: Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2329, p 2329 (2021)

Simple Summary Neurofibromatosis type 1 is a genetic disease that predisposes to tumors of the nervous system, primarily the neurofibroma. Plexiform neurofibromas (Pnfs) are of the greatest concern because of location, size, and frequent progression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55be31fc6fc927a08782d8dc81c81dd
https://pubmed.ncbi.nlm.nih.gov/34066061

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Biological Monitoring of Metal Ions Released from Hip Prostheses

Autor: Annamaria Nicolli, Andrea Trevisan, Pietro Ruggieri, Alberto Gambalunga, Isabella Bortoletti, Mariella Carrieri, Assunta Pozzuoli, Andrea Martinelli

Publikováno v: International Journal of Environmental Research and Public Health, Vol 17, Iss 3223, p 3223 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 9

The aim of this study was to evaluate the levels of As, Be, Bi, Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, Se, Tl, V, and Zn, by inductively coupled plasma-mass spectrometry (ICP-MS) in the urine of two groups of patients with two different types of metal-on-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd568a1f0ca3e18055555fcdb5a831b
https://www.mdpi.com/1660-4601/17/9/3223

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Unusual Domestic Source of Lead Poisoning

Autor: Annamaria Nicolli, Davide De Nuzzo, Grazia Genga Mina, Alberto Gambalunga, Andrea Martinelli, Fabiola Pasqualato, Isabella Bortoletti, Mariella Carrieri, Andrea Trevisan, Mario Cacciavillani

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 4374, p 4374 (2020)

Non-occupational lead poisoning is not rare, mainly occurring in domestic situations in children, but also in adults. Lead poisoning was observed in a 65 years-old woman non-exposed to risk that caught our attention with a diagnostic suspicion of acu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332f2378431423510442e259a443ae23
http://hdl.handle.net/11577/3342796

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Autor: Nicolò, Pettenuzzo, Leonardo, Brustolin, Elisa, Coltri, Alberto, Gambalunga, Federica, Chiara, Andrea, Trevisan, Barbara, Biondi, Chiara, Nardon, Dolores, Fregona

Publikováno v: ChemMedChem. 14(12)

This work is focused on the synthesis, characterization, and preliminary biological evaluation of bio-conjugated Au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::409ac2e6d02f528b90e813cf4c37aba8
https://pubmed.ncbi.nlm.nih.gov/31091012

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Ru(III) anticancer agents with aromatic and non-aromatic dithiocarbamates as ligands: Loading into nanocarriers and preliminary biological studies

Autor: Alberto Gambalunga, Federica Chiara, Simone Scintilla, Leonardo Brustolin, Chiara Nardon, Dolores Fregona, Andrea Trevisan

Publikováno v: Journal of Inorganic Biochemistry. 165:159-169

Since the discovery of cisplatin in the 1960s, other metal complexes have been investigated as potential antitumor agents to overcome the side-effects associated with the administration of the Pt-based drug. In line with our previous research, in thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa2c343c19b2987b2c4f5c191e02bb6
https://doi.org/10.1016/j.jinorgbio.2016.11.018

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Synthesis, chemical characterization and cancer cell growth-inhibitory activities of Cu(ii) and Ru(iii) aliphatic and aromatic dithiocarbamato complexes

Autor: Alberto Gambalunga, Andrea Trevisan, Nicolò Pettenuzzo, Dolores Fregona, N. Zuin Fantoni, Leonardo Brustolin, Federica Chiara, Luciano Marchiò, Santina Quarta, Chiara Nardon, Patrizia Pontisso

In this paper, we focused on the analysis of the effects mediated by different cyclic dithiocarbamic ligands (DTC) on three classes of antiproliferative coordination compounds, namely, Ru(III) complexes with the general formulae [Ru(DTC)3] and [Ru2(D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8d4556841758a8c395219b42d9b190
http://hdl.handle.net/11577/3287239

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Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1

Autor: Fiorella Calabrese, Francesco Ciscato, Alberto Gambalunga, Matteo Lambrughi, Massimo Rugge, Ionica Masgras, Vincenza Guzzardo, Elena Papaleo, Stefano Indraccolo, Giulia Guzzo, Stefania Edith Vuljan, Anna Maria Brunati, Paolo Bernardi, Elena Tibaldi, Matteo Curtarello, Federica Chiara, Andrea Rasola, Marco Pizzi, Giuseppe Cannino

Publikováno v: Cell Reports, Vol 18, Iss 3, Pp 659-672 (2017)

Mutations in neurofibromin, a Ras GTPase-activating protein, lead to the tumor predisposition syndrome neurofibromatosis type 1. Here, we report that cells lacking neurofibromin exhibit enhanced glycolysis and decreased respiration in a Ras/ERK-depen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd94004d682985f11f60c2d269bab6af
http://hdl.handle.net/11577/3218438

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Reliability of Urinary Excretion Rate Adjustment in Measurements of Hippuric Acid in Urine

Autor: Giovanni Battista Bartolucci, Andrea Trevisan, Annamaria Nicolli, Alberto Gambalunga, Federica Chiara, Mariella Carrieri

Publikováno v: International Journal of Environmental Research and Public Health, Vol 11, Iss 7, Pp 7036-7044 (2014)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health; Volume 11; Issue 7; Pages: 7036-7044

The urinary excretion rate is calculated based on short-term, defined time sample collections with a known sample mass, and this measurement can be used to remove the variability in urine concentrations due to urine dilution. Adjustment to the urinar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960eac1c07c60ccf1e18290f5e88ef61
https://doi.org/10.3390/ijerph110707036

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