Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Alberto, Darszon"'
Autor:
Haydee O. Hernández, Fernando Montoya, Paul Hernández-Herrera, Dan S. Díaz-Guerrero, Jimena Olveres, Hermes Bloomfield-Gadêlha, Alberto Darszon, Boris Escalante-Ramírez, Gabriel Corkidi
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26645- (2024)
The flagellar movement of the mammalian sperm plays a crucial role in fertilization. In the female reproductive tract, human spermatozoa undergo a process called capacitation which promotes changes in their motility. Only capacitated spermatozoa may
Externí odkaz:
https://doaj.org/article/97aef3ef8ab14c15aa45a64567c4429d
Autor:
Julio C. Chávez, Gabriela Carrasquel-Martínez, Sandra Hernández-Garduño, Arturo Matamoros Volante, Claudia L. Treviño, Takuya Nishigaki, Alberto Darszon
Publikováno v:
Cells, Vol 13, Iss 10, p 865 (2024)
As in most cells, intracellular pH regulation is fundamental for sperm physiology. Key sperm functions like swimming, maturation, and a unique exocytotic process, the acrosome reaction, necessary for gamete fusion, are deeply influenced by pH. Sperm
Externí odkaz:
https://doaj.org/article/e52fa18d2dd749298c48152739ed3527
Autor:
Esley Torres-García, Raúl Pinto-Cámara, Alejandro Linares, Damián Martínez, Víctor Abonza, Eduardo Brito-Alarcón, Carlos Calcines-Cruz, Gustavo Valdés-Galindo, David Torres, Martina Jabloñski, Héctor H. Torres-Martínez, José L. Martínez, Haydee O. Hernández, José P. Ocelotl-Oviedo, Yasel Garcés, Marco Barchi, Rocco D’Antuono, Ana Bošković, Joseph G. Dubrovsky, Alberto Darszon, Mariano G. Buffone, Roberto Rodríguez Morales, Juan Manuel Rendon-Mancha, Christopher D. Wood, Armando Hernández-García, Diego Krapf, Álvaro H. Crevenna, Adán Guerrero
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The presented Mean-Shift Super Resolution (MSSR) algorithm can extend spatial resolution within a single microscopy image. Its applicability extends across a wide range of experimental and instrumental configurations and it is compatible with other s
Externí odkaz:
https://doaj.org/article/999871293d6e426fa1366042d268e147
Autor:
Guillermina M. Luque, Liza J. Schiavi-Ehrenhaus, Martina Jabloñski, Paula A. Balestrini, Analia G. Novero, Nicolás I. Torres, Claudia E. Osycka-Salut, Alberto Darszon, Dario Krapf, Mariano G. Buffone
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The exclusive expression of CatSper in sperm and its critical role in sperm function makes this channel an attractive target for contraception. The strategy of blocking CatSper as a male, non-hormonal contraceptive has not been fully explored due to
Externí odkaz:
https://doaj.org/article/0e36ac12f38b4ed69cc8fdecf77c88e4
Autor:
Ruiming Zhao, Hui Dai, Rodolfo J. Arias, Gerardo A. De Blas, Gerardo Orta, Martín A. Pavarotti, Rong Shen, Eduardo Perozo, Luis S. Mayorga, Alberto Darszon, Steve A. N. Goldstein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The human voltage-gated proton channel (hHv1) maintains intracellular pH and membrane potential in sperm and neutrophils. Here, the authors show that albumin activates hHv1, by binding to the channel voltage sensor domains to enhance open probability
Externí odkaz:
https://doaj.org/article/c46008eddc1543f7b537b4b7900693ee
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The acrosome reaction (AR) is an exocytotic process essential for mammalian fertilization. It involves diverse physiological changes (biochemical, biophysical, and morphological) that culminate in the release of the acrosomal content to the extracell
Externí odkaz:
https://doaj.org/article/84cc7b1fd7b946bbb90bacdaa94dabae
Autor:
Alejandro Aguado-García, Daniel A. Priego-Espinosa, Andrés Aldana, Alberto Darszon, Gustavo Martínez-Mekler
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Capacitation is a complex maturation process mammalian sperm must undergo in the female genital tract to be able to fertilize an egg. This process involves, amongst others, physiological changes in flagellar beating pattern, membrane potential, intra
Externí odkaz:
https://doaj.org/article/9737a4098c1d472ea0b9be4a61fbbf69
Autor:
Daniel A Priego-Espinosa, Alberto Darszon, Adán Guerrero, Ana Laura González-Cota, Takuya Nishigaki, Gustavo Martínez-Mekler, Jorge Carneiro
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 3, p e1007605 (2020)
Intracellular calcium ([Ca2+]i) is a basic and ubiquitous cellular signal controlling a wide variety of biological processes. A remarkable example is the steering of sea urchin spermatozoa towards the conspecific egg by a spatially and temporally orc
Externí odkaz:
https://doaj.org/article/3a4225ee9dc14cdc9897a77c2c9f34dc
Autor:
Héctor Vicente Ramírez-Gómez, Vilma Jimenez Sabinina, Martín Velázquez Pérez, Carmen Beltran, Jorge Carneiro, Christopher D Wood, Idan Tuval, Alberto Darszon, Adán Guerrero
Publikováno v:
eLife, Vol 9 (2020)
Spermatozoa of marine invertebrates are attracted to their conspecific female gamete by diffusive molecules, called chemoattractants, released from the egg investments in a process known as chemotaxis. The information from the egg chemoattractant con
Externí odkaz:
https://doaj.org/article/393c9df832634660bb05bba5a6ca49ee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Intracellular pH (pHi) plays a crucial role in mammalian sperm physiology. However, it is a challenging task to acquire quantitative single sperm pHi images due to their small size and beating flagella. In this study, we established a robust pHi imag
Externí odkaz:
https://doaj.org/article/0032df5d0f24414da3fa8b7c53a4d032