Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Alberto, Cassetta"'
1
Akademický článek
On the Cholesterol Raising Effect of Coffee Diterpenes Cafestol and 16-O-Methylcafestol: Interaction with Farnesoid X Receptor
Autor: Elena Guercia, Federico Berti, Rita De Zorzi, Luciano Navarini, Silvano Geremia, Barbara Medagli, Marco De Conto, Alberto Cassetta, Cristina Forzato
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 11, p 6096 (2024)
The diterpene cafestol represents the most potent cholesterol-elevating compound known in the human diet, being responsible for more than 80% of the effect of coffee on serum lipids, with a mechanism still not fully clarified. In the present study, t
Externí odkaz: https://doaj.org/article/489d9c5423d54c3d8cf7d2c9d71edc48
Zobrazit plný text záznamu
2
Akademický článek
Molecular architecture of the glycogen- committed PP1/PTG holoenzyme
Autor: Marta Stefania Semrau, Gabriele Giachin, Sonia Covaceuszach, Alberto Cassetta, Nicola Demitri, Paola Storici, Graziano Lolli
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Glycogen metabolism is tightly regulated. Here the authors describe the 3D structure of the PP1/PTG protein complex, which plays a prominent role in the activation of glycogen synthesis and in the pathogenesis of Lafora disease, the most severe form
Externí odkaz: https://doaj.org/article/289b7fe616664ff4b5d17159ee926fb0
Zobrazit plný text záznamu
3
Akademický článek
Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions
Autor: Francesca Paoletti, Franci Merzel, Alberto Cassetta, Iza Ogris, Sonia Covaceuszach, Jože Grdadolnik, Doriano Lamba, Simona Golič Grdadolnik
Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2938-2949 (2021)
The Nerve Growth Factor (NGF) neurotrophin acts in the maintenance and growth of neuronal populations. Despite the detailed knowledge of NGF’s role in neuron physiology, the structural and mechanistic determinants of NGF bioactivity modulated by es
Externí odkaz: https://doaj.org/article/0e69f71ab9aa45d18dd7e75feb7b36e5
Zobrazit plný text záznamu
4
Akademický článek
Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria
Autor: Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent R. Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe F. Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Publikováno v: Pharmaceutics, Vol 15, Iss 2, p 502 (2023)
Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially druggable pathwa
Externí odkaz: https://doaj.org/article/0e262c2fdf194bf3a2bdc22d88bd3f07
Zobrazit plný text záznamu
6
Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2
Autor: Francesca Paoletti, Sonia Covaceuszach, Alberto Cassetta, Antonio N. Calabrese, Urban Novak, Petr Konarev, Jože Grdadolnik, Doriano Lamba, Simona Golič Grdadolnik
Publikováno v: Protein science, vol. 32, no. 2, e4563, pp. 1-14, 2023.
Protein Science
Protein science 32(2), e4563 (2023). doi:10.1002/pro.4563
Paoletti, Francesca; Covaceuszach, Sonia; Cassetta, Alberto; Calabrese, Antonio N; Novak, Urban; Konarev, Petr; Grdadolnik, Jože; Lamba, Doriano; Golič Grdadolnik, Simona (2023). Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2. Protein science, 32(2), e4563. Wiley-Blackwell 10.1002/pro.4563
Protein science 32(2), e4563 (2023). doi:10.1002/pro.4563
Nerve growth factor (NGF), the prototypical neurotrophic factor, is involved in the maintenance and growth of specific neuronal populations, whereas its precursor, proNGF, is involved in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8445c96cd75f3cd076573a1ef57854c4
Zobrazit plný text záznamu
7
Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg
Autor: Francesca, Paoletti, Sonia, Covaceuszach, Alberto, Cassetta, Antonio N, Calabrese, Urban, Novak, Petr, Konarev, Jože, Grdadolnik, Doriano, Lamba, Simona, Golič Grdadolnik
Publikováno v: Protein science : a publication of the Protein Society.
Nerve Growth Factor (NGF), the prototypical neurotrophic factor, is involved in the maintenance and growth of specific neuronal populations, whereas its precursor, proNGF, is involved in neuronal apoptosis. Binding of NGF or proNGF to TrkA, p75
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1560f047382ce3ec44c49821f4b44585
https://pubmed.ncbi.nlm.nih.gov/36605018
Zobrazit plný text záznamu
8
Akademický článek
The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan.
Autor: Sonia Covaceuszach, Manuela Bozzi, Maria Giulia Bigotti, Francesca Sciandra, Petr V Konarev, Andrea Brancaccio, Alberto Cassetta
Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0186110 (2017)
Dystroglycan (DG) is a highly glycosylated protein complex that links the cytoskeleton with the extracellular matrix, mediating fundamental physiological functions such as mechanical stability of tissues, matrix organization and cell polarity. A cruc
Externí odkaz: https://doaj.org/article/6b43a5eebcd049829b84eaa472055bb9
Zobrazit plný text záznamu
9
Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions
Autor: Doriano Lamba, Sonia Covaceuszach, Franci Merzel, Alberto Cassetta, Francesca Paoletti, Simona Golic Grdadolnik, Iza Ogris, Jože Grdadolnik
Publikováno v: Computational and Structural Biotechnology Journal 19 (2021): 2938–2949. doi:10.1016/j.csbj.2021.05.009
info:cnr-pdr/source/autori:Paoletti F.; Merzel F.; Cassetta A.; Ogris I.; Covaceuszach S.; Grdadolnik J.; Lamba D.; Golic Grdadolnik S./titolo:Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions/doi:10.1016%2Fj.csbj.2021.05.009/rivista:Computational and Structural Biotechnology Journal/anno:2021/pagina_da:2938/pagina_a:2949/intervallo_pagine:2938–2949/volume:19
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2938-2949 (2021)
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • High-resolution solution NMR structure of rhNGF has been determined. • Quinary interactions characterize ATP binding to rhNGF. • SPR, ITC and STD-NMR reveal ATP binding to rhNGF with mM affinity. • NMR and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad8b1ec3a685ab9524b7c239670f5be
https://doi.org/10.1016/j.csbj.2021.05.009
Zobrazit plný text záznamu
10
A novel water-resistant and thermally stable black lead halide perovskite, phenyl viologen lead iodide C22H18N2(PbI3)2
Autor: Nicola Demitri, Ombretta Tarquini, Francesca Menchini, Nicola Lisi, Luisa Barba, Alberto Cassetta, Alessandro Latini, Diego Di Girolamo, Marcello Colapietro, Simone Quaranta
Publikováno v: Dalton transactions (2003. Print) 49 (2020): 2616–2627. doi:10.1039/c9dt04148f
info:cnr-pdr/source/autori:Latini A.; Quaranta S.; Menchini F.; Lisi N.; Di Girolamo D.; Tarquini O.; Colapietro M.; Barba L.; Demitri N.; Cassetta A./titolo:A novel water-resistant and thermally stable black lead halide perovskite, phenyl viologen lead iodide C22H18N2(PbI3)2/doi:10.1039%2Fc9dt04148f/rivista:Dalton transactions (2003. Print)/anno:2020/pagina_da:2616/pagina_a:2627/intervallo_pagine:2616–2627/volume:49
A novel black organoammonium iodoplumbate semiconductor, namely phenyl viologen lead iodide C22H18N2(PbI3)2 (PhVPI), was successfully synthesized and characterized. This material showed physical and chemical properties suitable for photovoltaic appli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21afd76af73a6838ea71d9b751d39a3d
https://doi.org/10.1039/c9dt04148f
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje