Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Albertha JM Walhout"'
Autor:
Shivani Nanda, Marc‐Antoine Jacques, Wen Wang, Chad L Myers, L Safak Yilmaz, Albertha JM Walhout
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-21 (2023)
Abstract Metabolism is controlled to ensure organismal development and homeostasis. Several mechanisms regulate metabolism, including allosteric control and transcriptional regulation of metabolic enzymes and transporters. So far, metabolism regulati
Externí odkaz:
https://doaj.org/article/0097459255bb4655849a8d7955c05514
Autor:
Serkan Sayin, Brittany Rosener, Carmen G Li, Bao Ho, Olga Ponomarova, Doyle V Ward, Albertha JM Walhout, Amir Mitchell
Publikováno v:
eLife, Vol 12 (2023)
Drug metabolism by the microbiome can influence anticancer treatment success. We previously suggested that chemotherapies with antimicrobial activity can select for adaptations in bacterial drug metabolism that can inadvertently influence the host’
Externí odkaz:
https://doaj.org/article/8dbdb6a6921446178a0f0f6a43a5315f
Autor:
Lutfu Safak Yilmaz, Xuhang Li, Shivani Nanda, Bennett Fox, Frank Schroeder, Albertha JM Walhout
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 10, Pp 1-20 (2020)
Abstract Metabolism is a highly compartmentalized process that provides building blocks for biomass generation during development, homeostasis, and wound healing, and energy to support cellular and organismal processes. In metazoans, different cells
Externí odkaz:
https://doaj.org/article/1a6ba4b98cde4fe7916e99378d764e28
Autor:
Brittany Rosener, Serkan Sayin, Peter O Oluoch, Aurian P García González, Hirotada Mori, Albertha JM Walhout, Amir Mitchell
Publikováno v:
eLife, Vol 9 (2020)
Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently hamper microbiome growth, repeated drug administration can lead to microbiome evolutionary adap
Externí odkaz:
https://doaj.org/article/7f1eba23afaf4b36ad54274bc601c6ea
Autor:
Gabrielle E Giese, Melissa D Walker, Olga Ponomarova, Hefei Zhang, Xuhang Li, Gregory Minevich, Albertha JM Walhout
Publikováno v:
eLife, Vol 9 (2020)
Vitamin B12 is an essential micronutrient that functions in two metabolic pathways: the canonical propionate breakdown pathway and the methionine/S-adenosylmethionine (Met/SAM) cycle. In Caenorhabditis elegans, low vitamin B12, or genetic perturbatio
Externí odkaz:
https://doaj.org/article/5f1a40e24054414b90fb5d3766931b07
Autor:
Juan I Fuxman Bass, Carles Pons, Lucie Kozlowski, John S Reece‐Hoyes, Shaleen Shrestha, Amy D Holdorf, Akihiro Mori, Chad L Myers, Albertha JM Walhout
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 10, Pp 1-19 (2016)
Abstract Transcription factors (TFs) play a central role in controlling spatiotemporal gene expression and the response to environmental cues. A comprehensive understanding of gene regulation requires integrating physical protein–DNA interactions (
Externí odkaz:
https://doaj.org/article/a6b21d56d5cf41ec85dc315ca42fac2b
Autor:
Emma Watson, Viridiana Olin-Sandoval, Michael J Hoy, Chi-Hua Li, Timo Louisse, Victoria Yao, Akihiro Mori, Amy D Holdorf, Olga G Troyanskaya, Markus Ralser, Albertha JM Walhout
Publikováno v:
eLife, Vol 5 (2016)
Metabolic network rewiring is the rerouting of metabolism through the use of alternate enzymes to adjust pathway flux and accomplish specific anabolic or catabolic objectives. Here, we report the first characterization of two parallel pathways for th
Externí odkaz:
https://doaj.org/article/e41dab67960c492ea49983dc8cb5e514
Autor:
Kamesh Narasimhan, Samuel A Lambert, Ally WH Yang, Jeremy Riddell, Sanie Mnaimneh, Hong Zheng, Mihai Albu, Hamed S Najafabadi, John S Reece-Hoyes, Juan I Fuxman Bass, Albertha JM Walhout, Matthew T Weirauch, Timothy R Hughes
Publikováno v:
eLife, Vol 4 (2015)
Caenorhabditis elegans is a powerful model for studying gene regulation, as it has a compact genome and a wealth of genomic tools. However, identification of regulatory elements has been limited, as DNA-binding motifs are known for only 71 of the est
Externí odkaz:
https://doaj.org/article/f5fb0c93967e4b798b4863e1ee5801aa
Autor:
Shivani Nanda, Marc-Antoine Jacques, Wen Wang, Chad L Myers, L. Safak Yilmaz, Albertha JM Walhout
Metabolism is precisely controlled to ensure organismal development and homeostasis. Several mechanisms regulate metabolism, including allosteric control and transcriptional regulation of metabolic enzymes and transporters. So far, metabolism regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df918936f17cd4fba25544374e9073e1
https://doi.org/10.1101/2022.11.08.515576
https://doi.org/10.1101/2022.11.08.515576
