Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Albert W. Girotti"'
Autor:
Albert W. Girotti, Witold Korytowski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5697 (2024)
Anti-tumor photodynamic therapy (PDT) is a unique modality that employs a photosensitizer (PS), PS-exciting light, and O2 to generate cytotoxic oxidants. For various reasons, not all malignant cells in any given tumor will succumb to a PDT challenge.
Externí odkaz:
https://doaj.org/article/a28541786f3548a09b8ce4b7146928a4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11559 (2023)
Various studies have revealed that several cancer cell types can upregulate inducible nitric oxide synthase (iNOS) and iNOS-derived nitric oxide (NO) after moderate photodynamic treatment (PDT) sensitized by 5-aminolevulinic acid (ALA)-induced protop
Externí odkaz:
https://doaj.org/article/e00a6765dcc4421d9df6931048e3a81e
Autor:
Albert W. Girotti, Witold Korytowski
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102096- (2021)
Peroxidation of unsaturated phospholipids, glycolipids, and cholesterol in biological membranes under oxidative stress conditions can underlie a variety of pathological conditions, including atherogenesis, neurodegeneration, and carcinogenesis. Lipid
Externí odkaz:
https://doaj.org/article/14a40ab180cf47c4acae3398b2067d88
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 593 (2021)
Anti-tumor photodynamic therapy (PDT) is a unique oxidative stress-based modality that has proven highly effective on a variety of solid malignancies. PDT is minimally invasive and generates cytotoxic oxidants such as singlet molecular oxygen (1O2).
Externí odkaz:
https://doaj.org/article/02bc9862593d494aa2ede544cc7eb41a
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 11, Pp 3174-3184 (2010)
Sterol carrier protein-2 (SCP-2) plays an important role in cholesterol trafficking and metabolism in mammalian cells. The purpose of this study was to determine whether SCP-2, under oxidative stress conditions, might also traffic hydroperoxides of c
Externí odkaz:
https://doaj.org/article/b4f2b87bb5234ab08e0145b940250a55
Autor:
Albert W. Girotti
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 8, Pp 1529-1542 (1998)
Lipid peroxidation is a well known example of oxidative damage in cell membranes, lipoproteins, and other lipid-containing structures. Peroxidative modification of unsaturated phospholipids, glycolipids, and cholesterol can occur in reactions trigger
Externí odkaz:
https://doaj.org/article/a49cdb9bc98941249cb69183f6bcb625
Autor:
Albert W. Girotti, Witold Korytowski
Publikováno v:
Free Radical Research. :1-10
Recent studies have revealed that several cancer cell types can upregulate inducible nitric oxide synthase (iNOS) and iNOS-derived nitric oxide (NO) after a moderate photodynamic challenge sensitized by 5-aminolevulinic acid (ALA)-induced protoporphy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3bf70f6a690a0af1876530322db5f18
https://doi.org/10.20944/preprints202304.0819.v1
https://doi.org/10.20944/preprints202304.0819.v1
Publikováno v:
Critical reviews in oncology/hematology. 179
Low level nitric oxide (NO) produced by inducible NO synthase (iNOS) in many malignant tumors is known to play a key role in the survival and proliferation of tumor cells. NO can also induce or augment resistance to anti-tumor treatments such as plat
Autor:
Jonathan M, Fahey, Albert W, Girotti
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2451
Numerous studies have shown that low-flux nitric oxide (NO) in tumors produced mainly by inducible nitric oxide synthase (iNOS/NOS2) can signal for angiogenesis, inhibition of apoptosis, and promotion of cell growth, migration, and invasion. Studies