Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Albert Tousson"'
Autor:
Jian Chen, John D. Mountz, Hui-Chen Hsu, C. K. Edwards, A. Schottelius, PingAr Yang, Hui Xu, Craig A. Elmets, Albert Tousson, D. R. Kelly, Renata Bilion Ruiz Prado, X. Wang, Qi Wu, Mayumi Fujita
Publikováno v:
British Journal of Dermatology. 162:487-496
Background Chemokines are critical mediators of T-cell homing into inflamed skin. The complex nature of this multicellular response makes it difficult to analyse mechanisms mediating the early responses in vivo.
SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms
Autor:
Weifeng Song, Sadis Matalon, Yong Jian Zhou, Hong Guang Nie, Xue Feng Su, Zhiqian Gao, Hong Long Ji, Albert Tousson, Yu Xian He, Ji-Bin Peng, Ying Liao, Yi Jiang
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Among the multiple organ disorders caused by the severe acute respiratory syndrome coronavirus (SARS-CoV), acute lung failure following atypical pneumonia is the most serious and often fatal event. We hypothesized that two of the hydrophilic structur
Autor:
PingAr Yang, Robert W. Williams, David D. Chaplin, Hui-Chen Hsu, Robert H. Carter, Qi Wu, Albert Tousson, Jay K. Kolls, John D. Mountz, Tanja Guentert, Jian Chen, John H. Wang, Andrea L Stanus, John S. Yi, Robin G. Lorenz, Riley C. Myers, Hui Xu, Thuc-vy L. Le
Publikováno v:
Nature Immunology. 9:166-175
Interleukin 17 (IL-17) is a cytokine associated with inflammation, autoimmunity and defense against some bacteria. Here we show that IL-17 can promote autoimmune disease through a mechanism distinct from its proinflammatory effects. As compared with
Autor:
Henderika M.J. Oosterveld-Hut, Eric J. Sorscher, Albert Tousson, Bakhrom K. Berdiev, Estelle Cormet-Boyaka, Patricia A. Gonzales, Jeong S. Hong, Gergely L. Lukacs, Dale J. Benos, Catherine M. Fuller, Yawar J. Qadri
Publikováno v:
Journal of Biological Chemistry. 282:36481-36488
We present the evidence for a direct physical association of cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC), two major ion channels implicated in the pathophysiology of cystic fibrosis, a devastating i
Autor:
Jennifer Jones, Albert Tousson, Denise K. Oelschlager, William E. Grizzle, Ratna Chakrabarti, Tenekua Tapia
Publikováno v:
Cell Cycle. 6:2944-2952
LIM kinases (LIMK1 and LIMK2) are LIM domain containing serine/threonine kinases that modulate reorganization of actin cytoskeleton through inactivating phosphorylation of cofilin. The Rho family of small GTPases regulates the catalytic activity of L
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F329-F335
Renin release from juxtaglomerular granular cells is considered the rate-limiting step in activation of the renin-angiotensin system that helps to maintain body salt and water balance. Available assays to measure renin release are complex, indirect,
Autor:
William J. Cook, Xiaosheng Lei, David T. Curiel, Peter Nagi, Seiji Naito, Yosef S. Haviv, Minghui Wang, Koichi Takayama, John T. Lam, Delicia Carey, Albert Tousson
Publikováno v:
The Journal of Gene Medicine. 5:839-851
Background Systemic adenoviral (Ad) gene therapy for renal disorders is largely hampered by the unique architecture of the kidney. Consequently, currently available Ad vectors are of only limited therapeutic utility in the context of glomerular and f
Publikováno v:
Histochemistry and Cell Biology. 119:437-446
The acid-sensing ion channels (ASICs) are members of the DEG/ENaC superfamily of Na+ channels. Acid-gated cation currents have been detected in neurons from multiple regions of the brain including the cerebellum, but little is known about their molec
Autor:
Albert Tousson, Casey T. Weaver, Takekazu Kubo, Arman Saparov, Benjamin T. Weaver, James R. Oliver, Vincent Hurez, Michael J. Fuller
Publikováno v:
The Journal of Experimental Medicine
Limited frequencies of T cells express IL-2 in primary antigenic responses, despite activation marker expression and proliferation by most clonal members. To define the basis for restricted IL-2 expression, a videomicroscopic system and IL-2 reporter
Publikováno v:
The Anatomical Record. 267:7-16
C2 is a serum glycoprotein that is essential for activation of the classical and lectin pathways of the complement system. We reported previously that in transiently transfected COS cells, C2 accumulates in the endoplasmic reticulum-Golgi intermediat