Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Albert Schriefer"'
Autor:
Juliana A Silva, Ana Isabelle Pinheiro, Maria Luiza Dourado, Lilian Medina, Adriano Queiroz, Luiz Henrique Guimarães, Marcus Miranda Lessa, Ednaldo L Lago, Paulo Roberto L Machado, Mary E Wilson, Edgar M Carvalho, Albert Schriefer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0010390 (2022)
BackgroundLeishmaniases are neglected tropical diseases that inflict great burden to poor areas of the globe. Intense research has aimed to identify parasite genetic signatures predictive of infection outcomes. Consistency of diagnostic tools based o
Externí odkaz:
https://doaj.org/article/4aa5a4dfd46e4bc399d18ef1675ad27c
Autor:
Caroline R. Espada, Rubens M. Magalhães, Mario C. Cruz, Paulo R. Machado, Albert Schriefer, Edgar M. Carvalho, Valentín Hornillos, João M. Alves, Angela K. Cruz, Adriano C. Coelho, Silvia R.B. Uliana
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss , Pp 139-147 (2019)
In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available exhibit several limitations, mainly related to drug toxicity and reduced efficacy in some regions. Miltefosine (MF), the only oral
Externí odkaz:
https://doaj.org/article/e6fdcfd6e9714f0bbed7ebbb1c8e51f4
Autor:
Walker N. Oliveira, Andreza S. Dórea, Pedro P. Carneiro, Maurício T. Nascimento, Lucas P. Carvalho, Paulo R. L. Machado, Albert Schriefer, Olívia Bacellar, Edgar M. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Disseminated Leishmaniasis (DL) is an emerging and severe form of Leishmania (Viannia) braziliensis infection defined by the presence of 10 and up to more than 1,000 skin lesions. The mechanisms underlying parasite dissemination remain unknown. Genot
Externí odkaz:
https://doaj.org/article/273ece04941c49208708abd53a47ede8
Autor:
Tegwen Marlais, Tapan Bhattacharyya, Callum Pearson, Bathsheba L. Gardner, Safiyyah Marhoon, Stephanie Airs, Kiera Hayes, Andrew K. Falconar, Om Prakash Singh, Steven G. Reed, Sayda El-Safi, Shyam Sundar, Michael A. Miles, Albert Schriefer
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Diagnosis of visceral leishmaniasis (VL) relies on invasive and risky aspirate procedures, and confirmation of cure after treatment is unreliable. Detection of Leishmania donovani antigens in urine has the potential to provide both a non-invasive dia
Externí odkaz:
https://doaj.org/article/bf86e9d16ee946b399a9cf0a7e4eb508
Leishmania-Induced Dendritic Cell Migration and Its Potential Contribution to Parasite Dissemination
Autor:
Amanda Rebouças, Thaílla S. Silva, Lilian S. Medina, Bruno D. Paredes, Luciana S. Aragão, Bruno S. F. Souza, Valéria M. Borges, Albert Schriefer, Patricia S. T. Veras, Claudia I. Brodskyn, Juliana P. B. de Menezes
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1268 (2021)
Leishmania, an intracellular parasite species, causes lesions on the skin and in the mucosa and internal organs. The dissemination of infected host cells containing Leishmania is crucial to parasite survival and the establishment of infection. Migrat
Externí odkaz:
https://doaj.org/article/a015419fe689436c96112442306589b8
Autor:
Jamile Lago, Juliana A Silva, Lairton Borja, Deborah B M Fraga, Albert Schriefer, Sergio Arruda, Ednaldo Lago, Edgar M Carvalho, Olívia Bacellar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007532 (2019)
BackgroundCutaneous leishmaniasis (CL), caused by Leishmania braziliensis, is the most important presentation of tegumentary leishmaniasis (TL) in Latin American. While the role of dogs as reservoirs of Leishmania infantum, and the clinic features of
Externí odkaz:
https://doaj.org/article/5464a8efc99e4f98828a275a4c1314be
Autor:
Rosana Sousa, Viviane M. Andrade, Thomas Bair, Nicholas A. Ettinger, Luana Guimarães, Laura Andrade, Luiz H. Guimarães, Paulo R. L. Machado, Edgar M. Carvalho, Mary E. Wilson, Albert Schriefer
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Leishmania braziliensis is an intracellular parasite that resides mostly in macrophages. Both the parasite genome and the clinical disease manifestations show considerable polymorphism. Clinical syndromes caused by L. braziliensis include localized c
Externí odkaz:
https://doaj.org/article/9e487c1ea0e047a9b9755eb451a1b101
Autor:
Juliana Silva, Adriano Queiroz, Izabella Moura, Rosana S Sousa, Luiz Henrique Guimarães, Paulo Roberto Lima Machado, Marcus Lessa, Ednaldo Lago, Mary E Wilson, Albert Schriefer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006015 (2017)
American Tegumentary Leishmaniasis (ATL) caused by Leishmania braziliensis is endemic in Corte de Pedra, Northeast Brazil. Most L. braziliensis infections manifest as localized cutaneous leishmaniasis (CL). Disseminated manifestations include mucosal
Externí odkaz:
https://doaj.org/article/1eece6c1a7b6422d9f5c0d9a78f2181b
Autor:
Luiz Henrique Guimarães, Adriano Queiroz, Juliana A Silva, Silvana C Silva, Viviane Magalhães, Ednaldo L Lago, Paulo Roberto L Machado, Olívia Bacellar, Mary E Wilson, Stephen M Beverley, Edgar M Carvalho, Albert Schriefer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005100 (2016)
BACKGROUND:Atypical cutaneous leishmaniasis (ACL) has become progressively more frequent in Corte de Pedra, Northeast Brazil. Herein we characterize clinical presentation, antimony response, cytokine production and parasite strains prevailing in ACL.
Externí odkaz:
https://doaj.org/article/edb623f9e0cb40238c7c7f0aa7d84b76
Autor:
Lilian S Medina, Bruno Araújo Souza, Adriano Queiroz, Luiz Henrique Guimarães, Paulo Roberto Lima Machado, Edgar M Carvalho, Mary Edythe Wilson, Albert Schriefer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163284 (2016)
GP63 or leishmanolysin is the major surface protease of Leishmania spp. involved in parasite virulence and host cell interaction. As such, GP63 is a potential target of eventual vaccines against these protozoa. In the current study we evaluate the po
Externí odkaz:
https://doaj.org/article/3118985f0e41498198466c3c8539d785