Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Albert Salehi"'
Autor:
Israa Mohammad Al-Amily, Marie Sjögren, Pontus Duner, Mohammad Tariq, Claes B. Wollheim, Albert Salehi
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 557 (2023)
The activation of G Protein-Coupled Receptor 56 (GPR56), also referred to as Adhesion G-Protein-Coupled Ceceptor G1 (ADGRG1), by Collagen Type III (Coll III) prompts cell growth, proliferation, and survival, among other attributes. We investigated th
Externí odkaz:
https://doaj.org/article/f25366dd43244619aa0b89add67b5c83
Autor:
Elisa Vergari, Jakob G. Knudsen, Reshma Ramracheya, Albert Salehi, Quan Zhang, Julie Adam, Ingrid Wernstedt Asterholm, Anna Benrick, Linford J. B. Briant, Margarita V. Chibalina, Fiona M. Gribble, Alexander Hamilton, Benoit Hastoy, Frank Reimann, Nils J. G. Rorsman, Ioannis I. Spiliotis, Andrei Tarasov, Yanling Wu, Frances M. Ashcroft, Patrik Rorsman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Impaired glucagon secretion in patients with diabetes causes hypoglycemia. Here the authors show that therapeutic concentrations of insulin inhibit alpha-cell glucagon secretion by stimulating delta-cell insulin receptor and the release of somatostat
Externí odkaz:
https://doaj.org/article/9d4aeee6ff1d49cdae2f6687f5fe8637
Autor:
Davide Basco, Quan Zhang, Albert Salehi, Andrei Tarasov, Wanda Dolci, Pedro Herrera, Ioannis Spiliotis, Xavier Berney, David Tarussio, Patrik Rorsman, Bernard Thorens
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Glucagon secretion is promoted during hypoglycemia and inhibited by increased glucose levels. Here, Basco et al. show that glucokinase suppresses glucose-regulated glucagon secretion by modulating the intracellular ATP/ADP ratio and the closure of KA
Externí odkaz:
https://doaj.org/article/0248c76c4524407a805ca6e24356aff3
Autor:
Hayat Aljaibeji, Debasmita Mukhopadhyay, Abdul Khader Mohammed, Sarah Dhaiban, Mahmood Y. Hachim, Noha M. Elemam, Nabil Sulaiman, Albert Salehi, Jalal Taneera
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism under
Externí odkaz:
https://doaj.org/article/55019bc111574dcb8c6929f5a1fa0aee
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165668 (2016)
Metformin lowers diabetic blood glucose primarily by reducing hepatic gluconeogenesis and increasing peripheral glucose uptake. However, possible effects by metformin on beta-cell function are incompletely understood. We speculated that metformin mig
Externí odkaz:
https://doaj.org/article/1cf2ed1499484ae7b6ff84813beb8665
Autor:
Sergi Soriano, Paloma Alonso-Magdalena, Marta García-Arévalo, Anna Novials, Sarheed J Muhammed, Albert Salehi, Jan-Ake Gustafsson, Ivan Quesada, Angel Nadal
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31109 (2012)
Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical (EDC) used as the base compound in the manufacture of polycarbonate plastics. It alters pancreatic β-cell function and can be considered a risk factor for type 2 diabetes in rodents. He
Externí odkaz:
https://doaj.org/article/aeeebe0be17f439882d1e2539c0e31c4
Autor:
Stefanie Obermüller, Federico Calegari, Angus King, Anders Lindqvist, Ingmar Lundquist, Albert Salehi, Maura Francolini, Patrizia Rosa, Patrik Rorsman, Wieland B Huttner, Sebastian Barg
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8936 (2010)
Granins are major constituents of dense-core secretory granules in neuroendocrine cells, but their function is still a matter of debate. Work in cell lines has suggested that the most abundant and ubiquitously expressed granins, chromogranin A and B
Externí odkaz:
https://doaj.org/article/dc6cb480a3934b038bec420cb3830119
Autor:
Sandra Meidute Abaraviciene, Ingmar Lundquist, Juris Galvanovskis, Erik Flodgren, Björn Olde, Albert Salehi
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2182 (2008)
BackgroundType 2 diabetes often displays hyperlipidemia. We examined palmitate effects on pancreatic islet function in relation to FFA receptor GPR40, NO generation, insulin release, and the PPARgamma agonistic thiazolidinedione, rosiglitazone.Princi
Externí odkaz:
https://doaj.org/article/4aa6fdb3020c4c02b4edec44f860efe3
Autor:
Albert Salehi, Sandra Meidute Abaraviciene, Javier Jimenez-Feltstrom, Claes-Göran Ostenson, Suad Efendic, Ingmar Lundquist
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2165 (2008)
BACKGROUND:A distinctive feature of type 2 diabetes is inability of insulin-secreting beta-cells to properly respond to elevated glucose eventually leading to beta-cell failure. We have hypothesized that an abnormally increased NO production in the p
Externí odkaz:
https://doaj.org/article/7965af37df864792a126895489a4f4d6
Autor:
Sandra Meidute Abaraviciene, Ingmar Lundquist, Juris Galvanovskis, Erik Flodgren, Björn Olde, Albert Salehi
Publikováno v:
PLoS ONE, Vol 3, Iss 5 (2008)
Externí odkaz:
https://doaj.org/article/e51292f8f6f544aba663c714894528ac