Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Albert S. Peixoto"'
Autor:
Adriano B. Chaves-Filho, Albert S. Peixoto, Érique Castro, Tiago E. Oliveira, Luiz A. Perandini, Rafael J. Moreira, Railmara P. da Silva, Beatriz P. da Silva, Eduardo H. Moretti, Alexandre A. Steiner, Sayuri Miyamoto, Marcos Y. Yoshinaga, William T. Festuccia
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Total absence of adipose tissue (lipoatrophy) is associated with the development of severe metabolic disorders including hepatomegaly and fatty liver. Here, we sought to investigate the impact of severe lipoatrophy induced by deletion of peroxisome p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5997c6ffa3fab709aeeb64bdaa4eab08
Autor:
E. Moretti, Érique Castro, Tiago E. Oliveira, Cleyton R. Sobrinho, Alexandre A. Steiner, Mathieu Laplante, Rafael J. Moreira, Gustavo R. Gilio, Thayna S. Vieira, Milene Ortiz-Silva, Patricia Chimin, Caroline A Tomazelli, Mayara Franzoi Moreno, Raphael C Guimarães, Maynara L. Andrade, Luiz Augusto Perandini, William T. Festuccia, Patrícia Reckziegel, Albert S. Peixoto
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Deletion of mechanistic target of rapamycin complex 2 (mTORC2) essential component rapamycin insensitive companion of mTOR (Rictor) by a Cre recombinase under control of the broad, nonadipocyte-specific aP2/FABP4 promoter impairs thermoregulation and
Autor:
Ohara Augusto, Ana Iochabel Soares Moretti, Francisco R.M. Laurindo, R. Ryan Geyer, Daniela R. Truzzi, Asif Iqbal, Albert S. Peixoto
Publikováno v:
Journal of Biological Chemistry. 293:1450-1465
Protein-disulfide isomerase (PDI) is a ubiquitous dithiol–disulfide oxidoreductase that performs an array of cellular functions, such as cellular signaling and responses to cell-damaging events. PDI can become dysfunctional by post-translational mo
Autor:
Juliana Magdalon, Maynara L. Andrade, Mayara Franzoi Moreno, Milene Ortiz-Silva, Patricia Chimin, Sayuri Miyamoto, Thayna S. Vieira, Tiago E. Oliveira, Luiz Augusto Perandini, Rachael Ivison, Deepti Pant, Adriano B. Chaves-Filho, Érique Castro, Linus T.-Y. Tsai, Albert S. Peixoto, William T. Festuccia, Caroline A. Thomazelli, Marcos Yukio Yoshinaga, Thiago Belchior, Gustavo R. Gilio
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biochim Biophys Acta Mol Cell Biol Lipids
Universidade de São Paulo (USP)
instacron:USP
Biochim Biophys Acta Mol Cell Biol Lipids
The nutrient sensors peroxisome proliferator-activated receptor γ (PPARγ) and mechanistic target of rapamycin complex 1 (mTORC1) closely interact in the regulation of adipocyte lipid storage. The precise mechanisms underlying this interaction and w
Autor:
Mayara Franzoi Moreno, Rafael J. Moreira, Adriano B. Chaves-Filho, Telma Maria Tenório Zorn, Érique Castro, Marcos Yukio Yoshinaga, Thiago Belchior, Albert S. Peixoto, Bruno Cogliati, Fernanda Janku Cabral, Tiago E. Oliveira, Giuseppe Palmisano, William T. Festuccia, Janayna D. Lima, Leo Kei Iwai, Mychel R. P. T. Morais, Sayuri Miyamoto
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Scope Glucose homeostasis and progression of nonalcoholic fatty liver disease (NAFLD) and hepatomegaly in severe lipoatrophic mice and their modulation by intake of a diet rich in omega 3 (n-3) fatty acids (HFO) are evaluated. Methods and results Sev
Autor:
Filipe S. Lima, Ana Iochabel Soares Moretti, Railmara Pereira da Silva, Albert S. Peixoto, Francisco R.M. Laurindo, Marcela Franco Mineiro, Flavia Carla Meotti, Eliziane de Souza Patricio, Thaís L.S. Araujo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Extracellular surface protein disulfide isomerase-A1 (PDI) is involved in platelet aggregation, thrombus formation and vascular remodeling. PDI performs redox exchange with client proteins and, hence, its oxidation by extracellular molecul
Autor:
Érique Castro, Tiago E. Oliveira, Maynara L. Andrade, Alex Inague, Adriano B. Chaves-Filho, Marcos Yukio Yoshinaga, Naima Moustaid-Moussa, Albert S. Peixoto, Mayara Franzoi Moreno, Thiago Belchior, William T. Festuccia, Rafael J. Moreira, Milene Ortiz-Silva, Sayuri Miyamoto
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Scope The mechanisms and involvement of uncoupling protein 1 (UCP1) in the protection from obesity and insulin resistance induced by intake of a high-fat diet rich in omega-3 (n-3) fatty acids are investigated. Methods and results C57BL/6J mice are f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a135300c158142a8659a11463b252fc
Autor:
Christopher R Horne, Sarah G. Heath, Christine C. Winterbourn, Alexander V. Peskin, Christoph Göbl, Jennifer M. Crowther, Flavia Carla Meotti, Paul E. Pace, Renwick C. J. Dobson, Kelsey Kean, Albert S. Peixoto, P. Andrew Karplus
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
Peroxiredoxin 2 (Prdx2) is a thiol peroxidase with an active site Cys (C52) that reacts rapidly with H2O2 and other peroxides. The sulfenic acid product condenses with the resolving Cys (C172) to form a disulfide which is recycled by thioredoxin or G
Autor:
Pierre-Gilles Blanchard, Rafael J. Moreira, Érique Castro, Alexandre Caron, Marie Côté, Maynara L. Andrade, Tiago E. Oliveira, Milene Ortiz-Silva, Albert S. Peixoto, France Anne Dias, Yves Gélinas, Renata Guerra-Sá, Yves Deshaies, William T. Festuccia
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Objective We investigated whether PPARγ modulates adipose tissue BCAA metabolism, and whether this mediates the attenuation of obesity-associated insulin resistance induced by pharmacological PPARγ activation. Methods Mice with adipocyte deletion o
Autor:
Marina Burgos-Silva, Thiago Belchior, Juliana Magdalon, William T. Festuccia, Thayna S. Vieira, Mariane Tami Amano, Patricia Chimin, Maynara L. Andrade, Albert S. Peixoto, Niels Olsen Saraiva Câmara, Vivian A. Paschoal, Mayara Franzoi Moreno
Publikováno v:
Molecular Nutrition & Food Research. 62:1800283
Scope To test whether myeloid cells Tsc1 deletion and therefore constitutive activation of the nutrient sensor mTORC1 protects from high-fat diet (HFD)-induced obesity, glucose intolerance, and adipose tissue inflammation. Methods and results Mice wi