Výsledky vyhledávání - "Albert R. Wang"

Akademický článek

Targeted inhibition of BET proteins in HPV16-positive head and neck squamous cell carcinoma reveals heterogeneous transcriptional responses

Autor: Aakarsha Rao, Milan S. Stosic, Chitrasen Mohanty, Dhruthi Suresh, Albert R. Wang, Denis L. Lee, Kwangok P. Nickel, Darshan S. Chandrashekar, Randall J. Kimple, Paul F. Lambert, Christina Kendziorski, Trine B. Rounge, Gopal Iyer

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

Human papillomaviruses (HPV), most commonly HPV16, are associated with a subset of head and neck squamous cell carcinoma (HNSCC) tumors, primarily oropharyngeal carcinomas, with integration of viral genomes into host chromosomes associated with worse

Externí odkaz: https://doaj.org/article/29af87b7f5044f5da49d0afc0c1ed131

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Supplementary Data from Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog

Autor: Mario Otto, Gopal Iyer, Paul M. Harari, Bryan P. Bednarz, Eric A. Armstrong, Jamey P. Weichert, Lance T. Hall, Sorabh Singhal, Lauryn R. Werner, Chunrong Li, Dana C. Baiu, Albert R. Wang, Ankita Shahi, Mohamed Y. Elsaid

Supplementary Table 1. List of Antibodies used for Western and IHC. Supplementary Table 2. Plating efficiency (clonogenic assay). Supplementary Table 3. Statistical analysis of tumor growth rates in xenograft experiments (linear mixed effects model w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8c46e84296f62c1b7ffdf006ac8dc7
https://doi.org/10.1158/1535-7163.22504858

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Data from Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog

Antitumor alkyl phospholipid (APL) analogs comprise a group of structurally related molecules with remarkable tumor selectivity. Some of these compounds have shown radiosensitizing capabilities. CLR127 is a novel, clinical-grade antitumor APL ether a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b8d04632726f16eeb76d6bcb6d09a23
https://doi.org/10.1158/1535-7163.c.6537874.v1

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Abstract LB153: Inhibiting BRD4 as a proposed alternative therapeutic strategy for HPV16-associated head and neck squamous cell carcinoma

Autor: Dhruthi Suresh, Chitrasen Mohanty, Albert R. Wang, Christina Kendziorski, Gopal Iyer

Publikováno v: Cancer Research. 83:LB153-LB153

Integration of Human Papilloma Virus (HPV) 16 into human genomes is an integral event for cancer progression in Head and Neck Squamous Cell Carcinoma (HNSCC). There is a need to differentiate treatment for HPV-16 integrated HNSCC from other subtypes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71c6719531bbbfcda6e3412952c7bd94
https://doi.org/10.1158/1538-7445.am2023-lb153

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Abstract B038: Remodeling the extracellular matrix environment and establishing distinct immune cell profiles enables the formation of brain metastasis in non-small cell lung cancer adenocarcinoma

Autor: Albert R. Wang, Jared Brown, Andrew Baschnagel, Darya Buehler, Christina Kendziorski, Gopal Iyer

Publikováno v: Cancer Research. 83:B038-B038

Dissemination of tumor cells from the primary site of the lung to distant sites in non-small cell lung cancer (NSCLC) is poorly understood. With distinct mutation signatures in patients, altering pathways is critical to preventing tumor cell dissemin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e651d2beea16229a5ded4f1cc03deaa9
https://doi.org/10.1158/1538-7445.metastasis22-b038

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Gpnmb inhibits oligodendrocyte differentiation of adult neural stem cells by amplifying TGFβ1 signaling

Autor: Daniel Z. Radecki, Gopal Iyer, Abigail Johnson, Christian A. Overman, Albert R. Wang, Jayshree Samanta, Madison M. Thatcher

SummaryGli1 expressing neural stem cells, in the subventricular zone of the adult mammalian brain, respond to demyelination injury by differentiating into oligodendrocytes. We have identified Gpnmb as a novel regulator of oligodendrogenesis in Gli1 n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2768de6927ed4ae98df6aa7c4b642ee
https://doi.org/10.1101/2021.08.13.456269

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