Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Albert Quintana"'
Autor:
Kevin Aguilar, Carla Canal, Gemma Comes, Sandra Díaz-Clavero, Maria Angeles Llanos, Albert Quintana, Elisenda Sanz, Juan Hidalgo
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Mitochondrial diseases (MDs) are genetic disorders characterized by dysfunctions in mitochondria. Clinical data suggest that additional factors, beyond genetics, contribute to the onset and progression of this group of diseases, b
Externí odkaz:
https://doaj.org/article/e80395c7d42c4dc5a3428950a817c4d3
Autor:
Sebastián Zagmutt, Paula Mera, Ismael González-García, Kevin Ibeas, María del Mar Romero, Arnaud Obri, Beatriz Martin, Anna Esteve-Codina, M. Carmen Soler-Vázquez, Marianela Bastias-Pérez, Laia Cañes, Elisabeth Augé, Carme Pelegri, Jordi Vilaplana, Xavier Ariza, Jordi García, José Martinez-González, Núria Casals, Miguel López, Richard Palmiter, Elisenda Sanz, Albert Quintana, Laura Herrero, Dolors Serra
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-26 (2023)
Highlights Fatty acid metabolism and CPT1A in AgRP neurons show marked sex-dependent differences in the control of feeding. Cpt1a gene deletion in AgRP neurons increases energy expenditure in females but not in males. CPT1A in AgRP neurons is involve
Externí odkaz:
https://doaj.org/article/9eef829aeb3f49da853bf659361e7019
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S308- (2023)
Externí odkaz:
https://doaj.org/article/c17877a898004f64bff42b92051aa520
Autor:
Sofiia Rybas, Sinem Karaman, Kevin Aguilar, Lina Smeds, Johan Westö, Anna Ribeiro Xavier, Maiken Nedergaard, Albert Quintana, Juan Hidalgo Hidalgo, Petri Ala-Laurila, Kari Alitalo, Gulayse Ince Dunn, Anu Suomalainen
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S638- (2023)
Externí odkaz:
https://doaj.org/article/816b66c05e544dbd810e016c69f69fda
Autor:
Emma Puighermanal, Laia Castell, Anna Esteve-Codina, Su Melser, Konstantin Kaganovsky, Charleine Zussy, Jihane Boubaker-Vitre, Marta Gut, Stephanie Rialle, Christoph Kellendonk, Elisenda Sanz, Albert Quintana, Giovanni Marsicano, Miquel Martin, Marcelo Rubinstein, Jean-Antoine Girault, Jun B. Ding, Emmanuel Valjent
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed
Externí odkaz:
https://doaj.org/article/d4d48f37c7d94541a98488897d3e9b83
Autor:
Patricia Prada-Dacasa, Andrea Badell, Laura Sánchez-Benito, patrizia bianchi, Albert Quintana
Publikováno v:
Bio-Protocol, Vol 10, Iss 17 (2020)
Respiratory dysfunction is among the main cause of severe and fatal pathologies worldwide. The use of effective experimental models and methodologies for the study of the pulmonary pathophysiology is necessary to prevent, control and cure these disea
Externí odkaz:
https://doaj.org/article/b5ad8454ac41463e91ca66bc4365157d
Autor:
Alejandro Gella, Patricia Prada-Dacasa, Montserrat Carrascal, Andrea Urpi, Melania González-Torres, Joaquin Abian, Elisenda Sanz, Albert Quintana
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and r
Externí odkaz:
https://doaj.org/article/2ee59d68877041839468b29143c278fb
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8523 (2021)
Symbiosis between the mitochondrion and the ancestor of the eukaryotic cell allowed cellular complexity and supported life. Mitochondria have specialized in many key functions ensuring cell homeostasis and survival. Thus, proper communication between
Externí odkaz:
https://doaj.org/article/05bae7e012ef45fc87f02d020d38daa4
Autor:
Irene Bolea, Alejandro Gella, Elisenda Sanz, Patricia Prada-Dacasa, Fabien Menardy, Angela M Bard, Pablo Machuca-Márquez, Abel Eraso-Pichot, Guillem Mòdol-Caballero, Xavier Navarro, Franck Kalume, Albert Quintana
Publikováno v:
eLife, Vol 8 (2019)
Mitochondrial deficits in energy production cause untreatable and fatal pathologies known as mitochondrial disease (MD). Central nervous system affectation is critical in Leigh Syndrome (LS), a common MD presentation, leading to motor and respiratory
Externí odkaz:
https://doaj.org/article/32bf3e6cbd584e239e67faa01e0f2b0e
Autor:
Byron Chen, Jessica Hui, Kelsey S. Montgomery, Alejandro Gella, Irene Bolea, Elisenda Sanz, Richard D. Palmiter, Albert Quintana
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Inability of mitochondria to generate energy leads to severe and often fatal myoencephalopathies. Among these, Leigh syndrome (LS) is one of the most common childhood mitochondrial diseases; it is characterized by hypotonia, failure to thrive, respir
Externí odkaz:
https://doaj.org/article/289cace627004ee8a388e83c0f727295