Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease

Autor: Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates with Aβ patho

Externí odkaz: https://doaj.org/article/b027901016fa4e8ba7386d92b8d8e45e

Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts

Autor: Juan Lantero-Rodriguez, Agathe Vrillon, Aida Fernández-Lebrero, Paula Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner S. Brum, Emmanuel Cognat, Julien Dumurgier, Albert Puig-Pijoan, Irene Navalpotro-Gómez, Greta García-Escobar, Thomas K. Karikari, Eugeen Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, Marc Suárez-Calvet, Claire Paquet, Kaj Blennow

Publikováno v: Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2023)

Abstract Background Cerebrospinal fluid (CSF) p-tau235 is a novel biomarker highly specific of Alzheimer’s disease (AD). However, CSF p-tau235 has only been studied in well-characterized research cohorts, which do not fully reflect the patient land

Externí odkaz: https://doaj.org/article/77904aa0f595409998732159a64f7f99

Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment

Autor: Ainara Barguilla, Aida Fernández-Lebrero, Isabel Estragués-Gázquez, Greta García-Escobar, Irene Navalpotro-Gómez, Rosa María Manero, Víctor Puente-Periz, Jaume Roquer, Albert Puig-Pijoan

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Introduction: State of emergency caused by COVID-19 pandemic and subsequent lockdown hit Spain on 14th March 2020 and lasted until 21st June 2020. Social isolation measures were applied. Medical attention was focused on COVID-19. Primary and social c

Externí odkaz: https://doaj.org/article/1ceac9167f8b44d9bda83946d6ea3bc0

A head‐to‐head comparison of plasma phosphorylated tau assays in the real‐world memory clinic

Autor: Marc Suárez‐Calvet, Nicholas J. Ashton, Albert Puig‐Pijoan, Marta Milà‐Alomà, Aida Fernández‐Lebrero, Greta García‐Escobar, Fernándo González‐Ortiz, Przemyslaw Radoslaw Kac, Wagner Scheeren Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, Theresa A. Day, Jeffrey L. Dage, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Gallen Triana‐Baltzer, Setareh Moughadam, Hartmuth C. Kolb, Paula Ortiz‐Romero, Thomas K Karikari, Carolina Minguillón, Juan José Hernández Sánchez, Irene Navalpotro‐Gómez, Oriol Grau‐Rivera, Rosa María Manero, Víctor Puente‐Periz, Rafael de la Torre, Jaume Roquer, Henrik Zetterberg, Kaj Blennow

Publikováno v: Alzheimer's & Dementia. 18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0689b39f5169b9619993457f99e8210e
https://doi.org/10.1002/alz.065391

Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain

Autor: Alberto Villarejo-Galende, Elena García-Arcelay, Gerard Piñol-Ripoll, Antonio del Olmo-Rodríguez, Félix Viñuela, Mercè Boada, Emilio Franco-Macías, Almudena Ibañez de la Peña, Mario Riverol, Albert Puig-Pijoan, Pedro Abizanda-Soler, Rafael Arroyo, Miquel Baquero-Toledo, Inmaculada Feria-Vilar, Mircea Balasa, Ángel Berbel, Eloy Rodríguez-Rodríguez, Alba Vieira-Campos, Guillermo García-Ribas, Silvia Rodrigo-Herrero, Albert Lleó, Jorge Maurino

Publikováno v: Neurology and Therapy
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Neurology And Therapy
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

[Introduction] Limited information is available on people’s experiences of living with Alzheimer’s disease (AD) at earlier stages. This study assessed awareness of diagnosis among people with early-stage AD and its impact on different person-cent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c86b662518d483086ddc9a1c30264db
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=13667