Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Albert Mulenga"'
Autor:
Itabajara da Silva Vaz Junior, Stephen Lu, Antônio F. M. Pinto, Jolene K. Diedrich, John R. Yates, Albert Mulenga, Carlos Termignoni, José Marcos Ribeiro, Lucas Tirloni
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-20 (2024)
Abstract Background When feeding on a vertebrate host, ticks secrete saliva, which is a complex mixture of proteins, lipids, and other molecules. Tick saliva assists the vector in modulating host hemostasis, immunity, and tissue repair mechanisms. Wh
Externí odkaz:
https://doaj.org/article/99fc7c4fd72c4b37aa8e57f0649af10f
Autor:
Moiz Ashraf Ansari, Thu-Thuy Nguyen, Klaudia Izabela Kocurek, William Tae Heung Kim, Tae Kwon Kim, Albert Mulenga
Publikováno v:
Pathogens, Vol 13, Iss 7, p 560 (2024)
Ixodes scapularis is a blood-feeding obligate ectoparasite responsible for transmitting the Lyme disease (LD) agent, Borrelia burgdorferi. During the feeding process, I. scapularis injects B. burgdorferi into the host along with its saliva, facilitat
Externí odkaz:
https://doaj.org/article/82c0bb6784c4478ea97d0b776b277f34
Autor:
Thu-Thuy Nguyen, Tae Heung Kim, Emily Bencosme-Cuevas, Jacquie Berry, Alex Samuel Kiarie Gaithuma, Moiz Ashraf Ansari, Tae Kwon Kim, Lucas Tirloni, Zeljko Radulovic, James J Moresco, John R Yates, Albert Mulenga
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012032 (2024)
Lyme disease (LD) caused by Borrelia burgdorferi is among the most important human vector borne diseases for which there is no effective prevention method. Identification of tick saliva transmission factors of the LD agent is needed before the highly
Externí odkaz:
https://doaj.org/article/6061833a4c23447c8ecc79d6e1361558
Autor:
Tae Kwon Kim, Jéssica Waldman, Freddy Ibanez-Carrasco, Lucas Tirloni, Camila Waltero, Christiano Calixo, Gloria R. Braz, Albert Mulenga, Itabajara da Silva Vaz Junior, Carlos Logullo
Publikováno v:
Ticks and Tick-Borne Diseases, Vol 14, Iss 6, Pp 102251- (2023)
Studies on the transcriptional control of gene expression are crucial to understand changes in organism's physiological or cellular conditions. To obtain reliable data on mRNA amounts and the estimation of gene expression levels, it is crucial to nor
Externí odkaz:
https://doaj.org/article/9250b2ef2f0e457bab8ae25bc7c18dba
Autor:
Emily Bencosme-Cuevas, Tae Kwon Kim, Thu-Thuy Nguyen, Jacquie Berry, Jianrong Li, Leslie Garry Adams, Lindsey A. Smith, Syeda Areeha Batool, Daniel R. Swale, Stefan H. E. Kaufmann, Yava Jones-Hall, Albert Mulenga
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Tick serine protease inhibitors (serpins) play crucial roles in tick feeding and pathogen transmission. We demonstrate that Ixodes scapularis (Ixs) nymph tick saliva serpin (S) 41 (IxsS41), secreted by Borrelia burgdorferi (Bb)-infected ticks at high
Externí odkaz:
https://doaj.org/article/0277eab0661d40bb8474b674085ba139
Autor:
Albert Mulenga, Zeljko Radulovic, Lindsay Porter, Taylor Hollman Britten, Tae Kwon Kim, Lucas Tirloni, Alex Kiarie Gaithuma, Grace O. Adeniyi-Ipadeola, Jolene K. Dietrich, James J. Moresco, John R. Yates
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Ixodes scapularis long-term blood feeding behavior is facilitated by a tick secreted bio adhesive (tick cement) that attaches tick mouthparts to skin tissue and prevents the host from dislodging the attached tick. Understanding tick cement f
Externí odkaz:
https://doaj.org/article/b72626fb78f0460ebeeb45641900ac34
Autor:
Tae Kwon Kim, Lucas Tirloni, Emily Bencosme-Cuevas, Tae Heung Kim, Jolene K. Diedrich, John R. Yates, Albert Mulenga
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Lyme disease (LD) caused by Borrelia burgdorferi is the most prevalent tick-borne disease. There is evidence that vaccines based on tick proteins that promote tick transmission of B. burgdorferi could prevent LD. As Ixodes scapula
Externí odkaz:
https://doaj.org/article/8fceac292aff4486b0ea95dd25c9fd2b
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/8b9d5d572acc457eab26d3c371721ce4
Autor:
Tae Kwon Kim, Lucas Tirloni, Antônio F M Pinto, Jolene K Diedrich, James J Moresco, John R Yates, Itabajara da Silva Vaz, Albert Mulenga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0007758 (2020)
Amblyomma americanum ticks transmit more than a third of human tick-borne disease (TBD) agents in the United States. Tick saliva proteins are critical to success of ticks as vectors of TBD agents, and thus might serve as targets in tick antigen-based
Externí odkaz:
https://doaj.org/article/3d9ec60d6d424de1b5b2e2fa27c27b36
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008128 (2019)
Feeding and transmission of tick-borne disease (TBD) agents by ticks are facilitated by tick saliva proteins (TSP). Thus, defining functional roles of TSPs in tick evasion is expected to reveal potential targets in tick-antigen based vaccines to prev
Externí odkaz:
https://doaj.org/article/dc04e821fe614286b2f447c322558ff5