Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Albert Morales"'
Autor:
Sturla Magnus Grøndal, Anna Tutusaus, Loreto Boix, Maria Reig, Magnus Blø, Linn Hodneland, Gro Gausdal, Akil Jackson, Pablo Garcia de Frutos, James Bradley Lorens, Albert Morales, Montserrat Marí
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and aimsMetabolic dysfunction-associated steatohepatitis (MASH) is a significant health concern with limited treatment options. AXL, a receptor tyrosine kinase activated by the GAS6 ligand, promotes MASH through activation of hepatic stell
Externí odkaz:
https://doaj.org/article/6052153a12c545f1be1327af8224916c
Autor:
Carlos Cuño-Gómiz, Estefanía de Gregorio, Anna Tutusaus, Patricia Rider, Nuria Andrés-Sánchez, Anna Colell, Albert Morales, Montserrat Marí
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD
Externí odkaz:
https://doaj.org/article/14f4cf053fb949fcaca002d7051588d6
Autor:
Cristina de Dios, Xenia Abadin, Vicente Roca-Agujetas, Marina Jimenez-Martinez, Albert Morales, Ramon Trullas, Montserrat Mari, Anna Colell
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-23 (2023)
Abstract Background Persistent inflammatory response in the brain can lead to tissue damage and neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of inflammasomes, molecular platforms that drive inflammation through casp
Externí odkaz:
https://doaj.org/article/d67c08fc39e14f8ea51fdd4ce91c409e
Autor:
Albert Morales Moreno
Publikováno v:
Revista de Llengua i Dret - Journal of Language and Law, Vol 0, Iss 78, Pp 155-176 (2022)
L’11 de març de 2020, l’Organització Mundial de la Salut (OMS) classifica l’epidèmia de la SARS-CoV-2 com a pandèmia. En poques setmanes, el virus infecta milers de persones, paralitza l’economia mundial i els estats adopten mesures d’u
Externí odkaz:
https://doaj.org/article/3662133c691a4df48135a5c85948e9ca
Autor:
Joram Huckriede, Sara Bülow Anderberg, Albert Morales, Femke de Vries, Michael Hultström, Anders Bergqvist, José T. Ortiz-Pérez, Jan Willem Sels, Kanin Wichapong, Miklos Lipcsey, Marcel van de Poll, Anders Larsson, Tomas Luther, Chris Reutelingsperger, Pablo Garcia de Frutos, Robert Frithiof, Gerry A. F. Nicolaes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Coronavirus disease 19 (COVID-19) presents with disease severities of varying degree. In its most severe form, infection may lead to respiratory failure and multi-organ dysfunction. Here we study the levels and evolution of the damage associ
Externí odkaz:
https://doaj.org/article/42f33b11eed544279e2c99d11b536402
Autor:
Vicente Roca-Agujetas, Elisabet Barbero-Camps, Cristina de Dios, Petar Podlesniy, Xenia Abadin, Albert Morales, Montserrat Marí, Ramon Trullàs, Anna Colell
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-26 (2021)
Abstract Background Emerging evidence indicates that impaired mitophagy-mediated clearance of defective mitochondria is a critical event in Alzheimer’s disease (AD) pathogenesis. Amyloid-beta (Aβ) metabolism and the microtubule-associated protein
Externí odkaz:
https://doaj.org/article/cf8bece26c454c00987590519a3d4eb7
Autor:
Anna Tutusaus, Estefanía de Gregorio, Blanca Cucarull, Helena Cristóbal, Cristina Aresté, Isabel Graupera, Mar Coll, Anna Colell, Gro Gausdal, James B. Lorens, Pablo García de Frutos, Albert Morales, Montserrat Marí
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 349-368 (2020)
Background and Aims: GAS6 signaling, through the TAM receptor tyrosine kinases AXL and MERTK, participates in chronic liver pathologies. Here, we addressed GAS6/TAM involvement in Non-Alcoholic SteatoHepatitis (NASH) development. Methods: GAS6/TAM si
Externí odkaz:
https://doaj.org/article/44edac51eac143d78c187aa924fa98d2
Autor:
Neus Martínez-Bosch, Helena Cristóbal, Mar Iglesias, Meritxell Gironella, Luis Barranco, Laura Visa, Domenico Calafato, Silvia Jiménez-Parrado, Julie Earl, Alfredo Carrato, Noemí Manero-Rupérez, Mireia Moreno, Albert Morales, Carmen Guerra, Pilar Navarro, Pablo García de Frutos
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103797- (2022)
Summary: Background: Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. Here we explore the use of
Externí odkaz:
https://doaj.org/article/4de7d7f3e87f4b039869307abbfaa73f
Autor:
Anna Baulies, Joan Montero, Nuria Matías, Naroa Insausti, Oihana Terrones, Gorka Basañez, Carmen Vallejo, Laura Conde de La Rosa, Laura Martinez, David Robles, Albert Morales, Joaquin Abian, Montserrat Carrascal, Keigo Machida, Dinesh B.U. Kumar, Hidekazu Tsukamoto, Neil Kaplowitz, Carmen Garcia-Ruiz, José C. Fernández-Checa
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 164-177 (2018)
Cancer cells exhibit mitochondrial cholesterol (mt-cholesterol) accumulation, which contributes to cell death resistance by antagonizing mitochondrial outer membrane (MOM) permeabilization. Hepatocellular mt-cholesterol loading, however, promotes ste
Externí odkaz:
https://doaj.org/article/0ee1cf48437d4bc48e440ce37a0d5845
Autor:
Blanca Cucarull, Anna Tutusaus, Tania Hernáez-Alsina, Pablo García de Frutos, María Reig, Anna Colell, Montserrat Marí, Albert Morales
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1336 (2021)
Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment. Antioxidant supplements are becoming popular additio
Externí odkaz:
https://doaj.org/article/101bb45f60954e0a9df0d2f1710fc620