Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Albert M. Song"'
Autor:
Albert M. Song, Moon K. Song, H Yang, Dean T. Yamaguchi, Koichi Uyemura, Mark J. Rosenthal, EM Cornford, ME Ament
Publikováno v:
British Journal of Pharmacology. 158:442-450
Background and purpose: We have previously shown that treatment with zinc plus cyclo-(His-Pro) (CHP) significantly stimulated synthesis of the insulin degrading enzyme and lowered plasma insulin and blood glucose levels, alongside improving oral gluc
Publikováno v:
Metabolism. 54:1480-1489
Cyclo (his-pro), controlled-energy diet, soy protein hydrolysate (SPH), and raw vegetable food (RVF) are known to improve insulin sensitivity and body weight (BW) control. Enhancement of high cyclo (his-pro) content in SPH (HCS) was performed by refl
Autor:
Michael L. Steer, Vijay P. Singh, Lakshmi Bhagat, Albert M. Song, Gijs G.D. Van Acker, Ashok K. Saluja
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 283:G1166-G1174
Cyclooxygenase-2 (COX-2), a widely distributed enzyme, plays an important role in inflammation. We have studied the role of COX-2 in acute pancreatitis and pancreatitis-associated lung injury using both the pharmacological inhibition of COX-2 and gen
Autor:
Lakshmi Bhagat, Ashok K. Saluja, Gijs J.D. Van Acker, Vijay P. Singh, Albert M. Song, Michael L. Steer
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 283:G794-G800
Intrapancreatic activation of trypsinogen is believed to play a critical role in the initiation of acute pancreatitis, but mechanisms responsible for intrapancreatic trypsinogen activation during pancreatitis have not been clearly defined. In previou
Autor:
Antti J. Hietaranta, J. L. Frossard, Albert M. Song, Ashok K. Saluja, Hong Sik Lee, Vijay P. Singh, Lakshmi Bhagat, Michael L. Steer
Publikováno v:
Gut. 50:78-83
Background and aim: Recent studies have indicated that prior thermal stress causes upregulation of heat shock protein 70 (HSP70) expression in the pancreas and protects against secretagogue induced pancreatitis. The mechanisms responsible for the pro
Publikováno v:
Journal of Molecular and Genetic Medicine.
This review article evaluates the current knowledge in the prevention and treatment of diabetes and obesity. The relative abundance of food and lack of rigorous exercise common in modern life pose serious challenges in the incidence and treatment of
Autor:
Ashok K. Saluja, Antti J. Hietaranta, Michael L. Steer, Andreas Mykoniatis, Albert M. Song, Lakshmi Bhagat, Gijs J.D. Van Acker, Vijay P. Singh
Publikováno v:
Gastroenterology. 120:1818-1827
Background & Aims: The present study was undertaken to evaluate the role of serine proteases in regulating digestive enzyme secretion in pancreatic acinar cells. Methods: Isolated acini were stimulated by various secretagogues in the presence or abse
Autor:
Albert M. Song, Ashok K. Saluja, Lakshmi Bhagat, Gijs J.D. Van Acker, Michael L. Steer, Vijay P. Singh, Sudhir Agrawal
Publikováno v:
Gastroenterology. 122(1)
Background & Aims: Prior thermal stress induces heat shock protein 70 (HSP70) expression in the pancreas and protects against secretagogue-induced pancreatitis, but it is not clear that this thermal stress–induced protection is actually mediated by
Autor:
Ashok K. Saluja, Stephen P. Soltoff, Lakshmi Bhagat, Gijs J.D. Van Acker, Lewis C. Cantley, Albert M. Song, Vijay P. Singh, Michael L. Steer
Publikováno v:
The Journal of clinical investigation. 108(9)
Intra-acinar cell activation of digestive enzyme zymogens including trypsinogen is generally believed to be an early and critical event in acute pancreatitis. We have found that the phosphatidylinositol 3-kinase inhibitor wortmannin can reduce the in
Autor:
Lakshmi Bhagat, Albert M. Song, Michael L. Steer, Antti J. Hietaranta, Ashok K. Saluja, Vijay P. Singh
Publikováno v:
Biochemical and biophysical research communications. 280(1)
Intra-acinar cell nuclear factor-kappaB (NF-kappaB) and trypsinogen activation are early events in secretagogue-induced acute pancreatitis. We have studied the relationship between NF-kappaB and trypsinogen activation in rat pancreas. CCK analogue ca