Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Albert M. Mattocks"'
Autor:
William A. Wargin, J. Heyward Hull, Gary G. Koch, Albert M. Mattocks, Shelly L Chi, Lawrence J. Hak
Publikováno v:
Clinical Pharmacology and Therapeutics. 29:516-521
Several formulas for predicting creatinine clearance (Ccr) are used for adjusting drug dosages but limited data are available on their accuracy in patients with significant renal impairment or concurrent disease. We measured 144 Ccr in 103 patients a
Autor:
Harold M. Rosenthal, William T. Sawyer, Charles C. Pulliam, James R. Foster, B. Wesley Hadzija, Albert M. Mattocks
Publikováno v:
Biopharmaceutics & Drug Disposition. 3:301-310
The bioavailability of quinidine sulfate after oral administration of a commercial sustained-release quinidine tablet was compared with that of oral quinidine sulfate solution in 18 normal subjects. Three hundred milligrams of each product was admini
Autor:
Robert L. Kunka, Albert M. Mattocks
Publikováno v:
Journal of Pharmaceutical Sciences. 68:342-346
Intravenous bolus injections of 14C-labeled acetazolamide were made in rabbits. Plasma, urine, and washed red blood cell concentrations were measured, the latter indicating bound drug. AUTOAN and NONLIN were used to fit the plasma data to a linear tw
Publikováno v:
Journal of Pharmaceutical Sciences. 51:265-269
Flow properties of a series of emulsions containing methylcellulose 1,500 cps. in eight concentrations and corn oil in 10 concentrations were measured. Known equations for non-Newtonian flow were not satisfactory for these systems, and a new equation
Autor:
Sami F. Halaby, Albert M. Mattocks
Publikováno v:
Journal of Pharmaceutical Sciences. 54:52-55
Toxic symptoms have been observed in using peritoneal dialysis fluids containing 7 per cent dextrose. The one ingredient suspected as a possible cause of toxicity is sodium bisulfite, present in concentrations of 500mg./L. On reviewing the literature
Autor:
Albert M. Mattocks, George Milosovich
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 46:350-354
The effect of vapor pressure lowering, bisulfite, and washing procedures on the sorption of water by rubber closures has been studied. A logarithmic relationship between sorption of water by rubber closures and depression of vapor pressure due to ino
Autor:
George Milosovich, Albert M. Mattocks
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 46:377-381
An investigation of the use of nephelometry in evaluating rubber closures and washing procedures is reported. Evidence is presented that a nephelometric measure of haze can be of value in comparing closures, solutions, and washing procedures for prod
Autor:
Albert M. Mattocks, Wilbur A. Lazier
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 35:275-279
A number of readily wetted powders for the formation of acid‐containing ointments are described. These ointments were formulated for use in the chemical debridements of burns. Several were found to be as effective as pyruvic acid‐starch paste mix
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 46:236-239
A 4 x 4 x 3 x 2 factorial experiment was run to determine the effects of disintegrating agents, lubricants, binders, and hardness on tablet disintegration. A single tablet filler, starch-lactose equal parts, was used. Tablets were found to disintegra
Autor:
Latif S. Shenouda, Albert M. Mattocks
Publikováno v:
Journal of Pharmaceutical Sciences. 56:464-469
In order to obtain knowledge of the diffusion rates of pentobarbital, salicylic acid, and urea across the peritoneal membrane under ideal conditions, experiments with isolated rabbit mesentery were conducted. Diffusion coefficients of the drugs were