Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Albert Lowe"'
Publikováno v:
eLife, Vol 12 (2023)
The telencephalon and eye in mammals are originated from adjacent fields at the anterior neural plate. Morphogenesis of these fields generates telencephalon, optic-stalk, optic-disc, and neuroretina along a spatial axis. How these telencephalic and o
Externí odkaz:
https://doaj.org/article/6e69f24188d94f43b2caa8f124efa54c
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 743-756 (2016)
In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC)-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and disease.
Externí odkaz:
https://doaj.org/article/501fd9cd47104c5191fd7fabfa9eeabb
Autor:
Shelly Sorrells, Sara Nik, Mattie Casey, Rosannah C. Cameron, Harold Truong, Cristhian Toruno, Michelle Gulfo, Albert Lowe, Cicely Jette, Rodney A. Stewart, Teresa V. Bowman
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
RNA splicing factors are essential for the viability of all eukaryotic cells; however, in metazoans some cell types are exquisitely sensitive to disruption of splicing factors. Neuronal cells represent one such cell type, and defects in RNA splicing
Externí odkaz:
https://doaj.org/article/e528214ab2f54ebfa243703e24f54c74
Autor:
Wei Liu, Z. Jimmy Zhou, Yumei Li, Ales Cvekl, Sangbae Kim, Andre A. Hejazi, Leah A. Owen, Rui Chen, Seunghoon Lee, Rachayata Dharmat, Albert Lowe, Margaret M. DeAngelis, Akbar Shakoor, Denise J. Morgan, Jun Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10824-10833
Rod and cone photoreceptors are light-sensing cells in the human retina. Rods are dominant in the peripheral retina, whereas cones are enriched in the macula, which is responsible for central vision and visual acuity. Macular degenerations affect vis
Autor:
Harold Truong, Michelle Gulfo, Rosannah C. Cameron, Shelly Sorrells, Sara Nik, Rodney A. Stewart, Cicely A. Jette, Teresa V. Bowman, Mattie J. Casey, Cristhian Toruno, Albert Lowe
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
Disease Models & Mechanisms
Disease Models & Mechanisms
RNA splicing factors are essential for the viability of all eukaryotic cells; however, in metazoans some cell types are exquisitely sensitive to disruption of splicing factors. Neuronal cells represent one such cell type, and defects in RNA splicing
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 5, Pp 743-756 (2016)
Stem Cell Reports, Vol 6, Iss 5, Pp 743-756 (2016)
Summary In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC)-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and