Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Albert L. Ludolph"'
Autor:
Robert C. Bucelli, Manjit McNeill, Shafeeq Ladha, Angela Genge, Stephanie Fradette, Ivan Nestorov, John Ravits, Philip Van Damme, Roger Lane, Christopher J McDermott, Jonathan Glass, Merit Cudkowicz, Laura Fanning, C. Frank Bennett, Heiko Runz, Ih Chang, Hani Houshyar, Toby A. Ferguson, Alfred Sandrock, Alan Pestronk, Danielle Graham, Timothy M. Miller, Randall G. Trudell, Nazem Atassi, Peter M. Andersen, François Salachas, Nicholas J. Maragakis, Albert L. Ludolph, Pamela J. Shaw, Lorne Zinman, Alexander McCampbell
Publikováno v:
New England Journal of Medicine. 383:109-119
Background Tofersen is an antisense oligonucleotide that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein synthesis. Intrathecal administratio...
Autor:
Timothy, Miller, Merit, Cudkowicz, Pamela J, Shaw, Peter M, Andersen, Nazem, Atassi, Robert C, Bucelli, Angela, Genge, Jonathan, Glass, Shafeeq, Ladha, Albert L, Ludolph, Nicholas J, Maragakis, Christopher J, McDermott, Alan, Pestronk, John, Ravits, François, Salachas, Randall, Trudell, Philip, Van Damme, Lorne, Zinman, C Frank, Bennett, Roger, Lane, Alfred, Sandrock, Heiko, Runz, Danielle, Graham, Hani, Houshyar, Alexander, McCampbell, Ivan, Nestorov, Ih, Chang, Manjit, McNeill, Laura, Fanning, Stephanie, Fradette, Toby A, Ferguson
Publikováno v:
The New England journal of medicine. 383(2)
Tofersen is an antisense oligonucleotide that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein synthesis. Intrathecal administration of tofersen is being studied for the treatment of amyotrophic lateral s